Protein: TRIP4
Activating signal cointegrator 1 (ASC-1) (Thyroid receptor-interacting protein 4) (TR-interacting protein 4) (TRIP-4)

Gene: TRIP4
Organism: Homo sapiens
Interactions: 206
UniProt ID: Q15650

Gene Ontology (top 5):
GO:0002020 - protease binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1151353

ASCC3
Activating signal cointegrator 1 complex subunit 3

5

2

Small-scale

0.912

High

141503

DDX3X
ATP-dependent RNA helicase DDX3X

2

2

High-throughput

0.754

High

1151356

ASCC1
Activating signal cointegrator 1 complex subunit 1

7

0

Small-scale

0.710

High

1151386

ASCC2
Activating signal cointegrator 1 complex subunit 2

6

0

Small-scale

0.697

High

953896

IF4A1
Eukaryotic initiation factor 4A-I

1

2

High-throughput

0.691

High

396187

ESR1
Estrogen receptor

3

5

Small-scale

0.641

High

1151375

ALKB3
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3

3

0

High-throughput

0.638

High

1045324

TF65
Transcription factor p65

2

1

Small-scale

0.629

High

658197

RS3
Small ribosomal subunit protein uS3

3

0

High-throughput

0.622

High

992768

RACK1
Small ribosomal subunit protein RACK1

3

0

High-throughput

0.622

High

207552

DHX15
ATP-dependent RNA helicase DHX15

1

1

High-throughput

0.618

High

315626

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.618

High

608613

DDX5
Probable ATP-dependent RNA helicase DDX5

1

1

High-throughput

0.618

High

684252

DDX6
Probable ATP-dependent RNA helicase DDX6

1

2

High-throughput

0.618

High

1062477

DHX9
ATP-dependent RNA helicase A

1

2

High-throughput

0.618

High

1118037

DX39B
Spliceosome RNA helicase DDX39B

1

3

High-throughput

0.618

High

1151346

DHX30
ATP-dependent RNA helicase DHX30

1

2

High-throughput

0.618

High

1151362

DDX1
ATP-dependent RNA helicase DDX1

1

2

High-throughput

0.618

High

1151384

DDX24
ATP-dependent RNA helicase DDX24

1

2

High-throughput

0.618

High

1151392

DDX21
Nucleolar RNA helicase 2

1

2

High-throughput

0.618

High

508023

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

1

High-throughput

0.602

High

1151365

ESR2
Estrogen receptor beta

2

4

Small-scale

0.595

High

447059

NPM
Nucleophosmin

2

0

High-throughput

0.585

High

969880

RS16
Small ribosomal subunit protein uS9

2

0

High-throughput

0.585

High

172847

XPO1
Exportin-1

2

2

High-throughput

0.584

High

345876

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

2

High-throughput

0.584

High

789504

PPARG
Peroxisome proliferator-activated receptor gamma

2

6

Small-scale

0.571

High

469293

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

2

0

High-throughput

0.559

High

667314

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

0

High-throughput

0.559

High

954140

RS20
Small ribosomal subunit protein uS10

2

0

High-throughput

0.559

High

969238

RS8
Small ribosomal subunit protein eS8

2

0

High-throughput

0.547

High

665101

COT2
COUP transcription factor 2

1

3

High-throughput

0.541

High

533348

THB
Thyroid hormone receptor beta

1

5

Small-scale

0.527

High

625821

RXRA
Retinoic acid receptor RXR-alpha

1

4

Small-scale

0.527

High

626241

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

Small-scale

0.527

High

1151390

NEK6
Serine/threonine-protein kinase Nek6

1

0

Small-scale

0.526

High

608974

XBP1
X-box-binding protein 1

1

0

High-throughput

0.518

High

938452

PAX9
Paired box protein Pax-9

1

0

High-throughput

0.518

High

161815

RIOK3
Serine/threonine-protein kinase RIO3

1

0

High-throughput

0.513

High

295175

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.513

High

625409

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

765547

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.513

High

839554

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.513

High

860761

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

913498

KIF11
Kinesin-like protein KIF11

1

0

High-throughput

0.513

High

939333

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.513

High

973451

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

1151388

CDT1
DNA replication factor Cdt1

1

0

High-throughput

0.513

High

1151406

G3BP2
Ras GTPase-activating protein-binding protein 2

1

0

High-throughput

0.513

High

429948

JUN
Transcription factor Jun

1

0

Small-scale

0.504

High

549325

SRF
Serum response factor

1

0

Small-scale

0.504

High

1151338

NCOA1
Nuclear receptor coactivator 1

1

0

Small-scale

0.504

High

520587

RARA
Retinoic acid receptor alpha

1

6

Small-scale

0.501

High

1151366

CBP
CREB-binding protein

1

1

Small-scale

0.501

High

1067368

EP300
Histone acetyltransferase p300

1

1

Small-scale

0.481

High

122775

KIF2A
Kinesin-like protein KIF2A

1

1

High-throughput

0.479

High

157423

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

270811

ROCK2
Rho-associated protein kinase 2

1

1

High-throughput

0.479

High

400885

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

624072

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

1

High-throughput

0.479

High

775111

FUS
RNA-binding protein FUS

1

3

High-throughput

0.479

High

854077

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.479

High

899924

FXR1
RNA-binding protein FXR1

1

1

High-throughput

0.479

High

936552

AF17
Protein AF-17

1

1

High-throughput

0.479

High

1024596

VIGLN
Vigilin

1

1

High-throughput

0.479

High

1027479

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.479

High

1032990

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

1056747

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.479

High

1063273

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.479

High

1089680

ILF3
Interleukin enhancer-binding factor 3

1

1

High-throughput

0.479

High

1151248

MED1
Mediator of RNA polymerase II transcription subunit 1

1

2

High-throughput

0.479

High

1151344

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

1151347

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

1

High-throughput

0.479

High

1151348

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1151351

LUZP1
Leucine zipper protein 1

1

3

High-throughput

0.479

High

1151368

MED12
Mediator of RNA polymerase II transcription subunit 12

1

1

High-throughput

0.479

High

1151376

MED15
Mediator of RNA polymerase II transcription subunit 15

1

2

High-throughput

0.479

High

1151377

SRPK1
SRSF protein kinase 1

1

1

High-throughput

0.479

High

1151395

BCLF1
Bcl-2-associated transcription factor 1

1

1

High-throughput

0.479

High

1151399

XPO7
Exportin-7

1

2

High-throughput

0.479

High

1151402

BRPF3
Bromodomain and PHD finger-containing protein 3

1

1

High-throughput

0.479

High

1151411

RUVB2
RuvB-like 2

1

1

High-throughput

0.479

High

1151412

RUVB1
RuvB-like 1

1

1

High-throughput

0.479

High

1151413

TR150
Thyroid hormone receptor-associated protein 3

1

2

High-throughput

0.479

High

1151415

PKP3
Plakophilin-3

1

1

High-throughput

0.479

High

96689

E9PAV9
G patch domain-containing protein 4

1

0

High-throughput

0.458

High

162580

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.458

High

228266

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

250627

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.458

High

258894

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.458

High

270937

CLAP2
CLIP-associating protein 2

1

0

High-throughput

0.458

High

279374

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

282384

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.458

High

285936

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.458

High

361256

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.458

High

411991

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

457096

CAN1
Calpain-1 catalytic subunit

1

0

High-throughput

0.458

High

464267

FUMH
Fumarate hydratase, mitochondrial

1

0

High-throughput

0.458

High

537213

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

539334

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

0

High-throughput

0.458

High

558163

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

577768

PLAK
Junction plakoglobin

1

0

High-throughput

0.458

High

586712

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

610677

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.458

High

611885

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.458

High

612651

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.458

High

637138

CSRP1
Cysteine and glycine-rich protein 1

1

0

Small-scale

0.458

High

680367

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

687424

PTBP1
Polypyrimidine tract-binding protein 1

1

0

High-throughput

0.458

High

692069

MARK3
MAP/microtubule affinity-regulating kinase 3

1

0

High-throughput

0.458

High

695552

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

697544

PYR1
Multifunctional protein CAD

1

0

High-throughput

0.458

High

785193

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.458

High

810124

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

842387

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.458

High

853270

CBX5
Chromobox protein homolog 5

1

0

High-throughput

0.458

High

858938

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

859844

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.458

High

862853

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.458

High

880312

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.458

High

956305

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.458

High

958108

ARP3
Actin-related protein 3

1

0

High-throughput

0.458

High

972421

RS14
Small ribosomal subunit protein uS11

1

0

High-throughput

0.458

High

972872

RS18
Small ribosomal subunit protein uS13

1

0

High-throughput

0.458

High

973190

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

975710

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

977257

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.458

High

978543

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

978961

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

979717

H4
Histone H4

1

0

High-throughput

0.458

High

981835

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.458

High

985182

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.458

High

986057

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.458

High

992486

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.458

High

994555

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.458

High

996168

EF1A1
Elongation factor 1-alpha 1

1

0

High-throughput

0.458

High

996963

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.458

High

1014522

SMAD3
Mothers against decapentaplegic homolog 3

1

0

High-throughput

0.458

High

1039231

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

1057757

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.458

High

1088364

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.458

High

1107747

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1125112

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

0

High-throughput

0.458

High

1130271

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.458

High

1146678

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

1147163

ELOB
Elongin-B

1

0

High-throughput

0.458

High

1151339

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.458

High

1151340

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.458

High

1151341

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.458

High

1151342

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

1151345

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.458

High

1151349

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1151350

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1151352

RAVR1
Ribonucleoprotein PTB-binding 1

1

0

High-throughput

0.458

High

1151354

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

1151355

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

1151358

LIPB2
Liprin-beta-2

1

0

High-throughput

0.458

High

1151359

TTL11
Tubulin polyglutamylase TTLL11

1

0

High-throughput

0.458

High

1151361

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1151363

LAR4B
La-related protein 4B

1

0

High-throughput

0.458

High

1151367

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.458

High

1151369

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.458

High

1151370

ZC21A
Zinc finger C2HC domain-containing protein 1A

1

0

High-throughput

0.458

High

1151371

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1151372

CNDP2
Cytosolic non-specific dipeptidase

1

0

High-throughput

0.458

High

1151373

RL10L
Ribosomal protein uL16-like

1

0

High-throughput

0.458

High

1151374

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1151378

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1151379

SH3G1
Endophilin-A2

1

0

High-throughput

0.458

High

1151380

TRI56
E3 ubiquitin-protein ligase TRIM56

1

0

High-throughput

0.458

High

1151381

MCMBP
Mini-chromosome maintenance complex-binding protein

1

0

High-throughput

0.458

High

1151382

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.458

High

1151385

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

0

High-throughput

0.458

High

1151387

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

High-throughput

0.458

High

1151389

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1151391

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

1151393

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

0

High-throughput

0.458

High

1151394

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.458

High

1151396

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

High-throughput

0.458

High

1151397

MED13
Mediator of RNA polymerase II transcription subunit 13

1

0

High-throughput

0.458

High

1151398

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.458

High

1151400

RCOR1
REST corepressor 1

1

0

High-throughput

0.458

High

1151401

AGO2
Protein argonaute-2

1

0

High-throughput

0.458

High

1151403

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

1151405

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

1151407

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.458

High

1151409

SRRM2
Serine/arginine repetitive matrix protein 2

1

0

High-throughput

0.458

High

1151410

SMC3
Structural maintenance of chromosomes protein 3

1

0

High-throughput

0.458

High

1151416

RBM8A
RNA-binding protein 8A

1

0

High-throughput

0.458

High

942632

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.445

High

947350

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

0

Small-scale

0.438

High

240147

FGF17
Fibroblast growth factor 17

1

0

High-throughput

0.426

High

290574

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.426

High

1151360

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.426

High

1151364

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.426

High

1099623

NOGG
Noggin

1

0

High-throughput

0.279

Low

133029

MATN2
Matrilin-2

1

0

High-throughput

0.249

Low

784618

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.249

Low

829401

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

1151343

WDR87
WD repeat-containing protein 87

1

0

High-throughput

0.249

Low

1151357

TXND5
Thioredoxin domain-containing protein 5

1

0

High-throughput

0.249

Low

1151404

COR1C
Coronin-1C

1

0

High-throughput

0.249

Low

1151408

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.249

Low

1151414

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.249

Low

288173

CLC3A
C-type lectin domain family 3 member A

1

0

High-throughput

0.232

Low

1151383

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025