HitPredict

Interactor 1: BMPR2 (Q13873)
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)
Gene: BMPR2

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0005912 - adherens junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1038 Hs			1 232
+	Hs
		901153 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		893991 BMPR2_HUMAN (1-1038): 0: 868: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		852467 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		925266 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		892361 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		545365 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		900458 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		950982 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		436293 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		915666 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120428 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		1046387 BMPR2_HUMAN (1-1038): 0: 868: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Dm
		87957 D3DMF6_DROME (186-1009): 7.28e-131: 421: 14.44		RHO1_DROME (13-197): 6.57e-96: 279: 42.70
+	Mm
		983317 TGFR2_MOUSE (8-504): 1.23e-137: 427: 30.19		RAC2_MOUSE (11-201): 1.33e-76: 230: 38.74
+	Hs
		738321 BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		738320 BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		738322 BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Mm
		956267 TGFR2_MOUSE (8-504): 1.23e-137: 427: 30.19		RHOD_MOUSE (15-189): 2.08e-46: 154: 39.43
+	Hs
		436181 BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		738323 BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94