HitPredict

Interactor 1: C1D (Q13901)
Nuclear nucleic acid-binding protein C1D (hC1D)
Gene: C1D

Interactor 2: EXOS4 (Q9NPD3)
Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A)
Gene: EXOSC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000176 - nuclear exosome (RNase complex) GO:0000178 - exosome (RNase complex) GO:0000460 - maturation of 5.8S rRNA GO:0005634 - nucleus GO:0005654 - nucleoplasm and 2 others more... GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 141 Hs			1 245
+	Hs
		1047034 C1D_HUMAN (1-141): 2.25e-80: 235: 100.00		EXOS8_HUMAN (1-234): 4.22e-62: 197: 18.73
+	Hs
		1047040 C1D_HUMAN (1-141): 2.25e-80: 235: 100.00		EXOS5_HUMAN (2-239): 3.39e-52: 170: 26.25
+	Hs
		1047019 C1D_HUMAN (1-141): 2.25e-80: 235: 100.00		EXOS7_HUMAN (3-244): 6.35e-51: 169: 16.01
+	Hs
		1047021 C1D_HUMAN (1-141): 2.25e-80: 235: 100.00		EXOS6_HUMAN (6-232): 3.11e-47: 159: 29.05