Protein: PAIP1
Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1)

Gene: PAIP1
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q9H074

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006413 - translational initiation
GO:0006446 - regulation of translational initiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

550459

PABP1
Polyadenylate-binding protein 1

13

13

Small-scale

0.989

High

1409765

PAIP2
Polyadenylate-binding protein-interacting protein 2

4

1

High-throughput

0.895

High

1102089

PABP4
Polyadenylate-binding protein 4

3

13

High-throughput

0.861

High

1197177

PAP1L
Polyadenylate-binding protein 1-like

3

13

High-throughput

0.861

High

326026

UBR5
E3 ubiquitin-protein ligase UBR5

2

5

Small-scale

0.768

High

1429220

MKRN2
E3 ubiquitin-protein ligase makorin-2

4

3

High-throughput

0.694

High

1066774

NCBP1
Nuclear cap-binding protein subunit 1

1

4

High-throughput

0.691

High

1314834

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

1

5

High-throughput

0.691

High

1429458

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

4

High-throughput

0.691

High

1429472

PAI2B
Polyadenylate-binding protein-interacting protein 2B

1

1

High-throughput

0.691

High

172209

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

3

14

High-throughput

0.667

High

1111864

TRA2A
Transformer-2 protein homolog alpha

3

11

High-throughput

0.667

High

1429464

ZCHC3
Zinc finger CCHC domain-containing protein 3

3

2

High-throughput

0.667

High

1429465

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

3

2

High-throughput

0.667

High

1314789

SUV3
ATP-dependent RNA helicase SUPV3L1, mitochondrial

1

0

High-throughput

0.656

High

1090296

ELAV2
ELAV-like protein 2

2

13

High-throughput

0.628

High

1245734

LARP1
La-related protein 1

2

9

High-throughput

0.628

High

1307519

RBM45
RNA-binding protein 45

2

16

High-throughput

0.628

High

1330012

CELF5
CUGBP Elav-like family member 5

2

9

High-throughput

0.628

High

213488

CTIF
CBP80/20-dependent translation initiation factor

1

9

High-throughput

0.618

High

953992

IF4A1
Eukaryotic initiation factor 4A-I

1

18

Small-scale

0.618

High

1325004

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

3

High-throughput

0.618

High

1429474

DD19B
ATP-dependent RNA helicase DDX19B

1

19

High-throughput

0.618

High

1259154

LARP4
La-related protein 4

2

8

High-throughput

0.611

High

1365666

LAR4B
La-related protein 4B

2

8

High-throughput

0.611

High

1370105

RENT1
Regulator of nonsense transcripts 1

2

5

High-throughput

0.611

High

591833

H2AX
Histone H2AX

3

1

High-throughput

0.609

High

519420

MYB
Transcriptional activator Myb

2

1

High-throughput

0.606

High

132286

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

Small-scale

0.578

High

939431

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

10

Small-scale

0.569

High

135344

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

13

High-throughput

0.536

High

193816

PER1
Period circadian protein homolog 1

1

1

High-throughput

0.536

High

230569

KIF1C
Kinesin-like protein KIF1C

1

3

High-throughput

0.536

High

250815

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

13

Small-scale

0.536

High

256680

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

4

High-throughput

0.536

High

271096

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

1

High-throughput

0.536

High

275919

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

2

High-throughput

0.536

High

284225

SRS10
Serine/arginine-rich splicing factor 10

1

14

High-throughput

0.536

High

286278

CSDE1
Cold shock domain-containing protein E1

1

1

Small-scale

0.536

High

295237

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

18

Small-scale

0.536

High

350990

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

2

High-throughput

0.536

High

462627

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

6

High-throughput

0.536

High

576538

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

10

High-throughput

0.536

High

581585

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

1

5

High-throughput

0.536

High

870973

IREB2
Iron-responsive element-binding protein 2

1

1

High-throughput

0.536

High

889809

CLK3
Dual specificity protein kinase CLK3

1

5

High-throughput

0.536

High

994789

YBOX1
Y-box-binding protein 1

1

1

High-throughput

0.536

High

1114252

CUL3
Cullin-3

1

2

High-throughput

0.536

High

1120330

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

13

Small-scale

0.536

High

1145359

RNPS1
RNA-binding protein with serine-rich domain 1

1

15

High-throughput

0.536

High

1148787

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

15

High-throughput

0.536

High

1226044

LAR1B
La-related protein 1B

1

9

High-throughput

0.536

High

1290713

ZCH18
Zinc finger CCCH domain-containing protein 18

1

2

High-throughput

0.536

High

1314693

SRRM1
Serine/arginine repetitive matrix protein 1

1

2

High-throughput

0.536

High

1348124

PUM2
Pumilio homolog 2

1

1

High-throughput

0.536

High

1370239

DAZL
Deleted in azoospermia-like

1

12

High-throughput

0.536

High

1387887

PABP5
Polyadenylate-binding protein 5

1

13

High-throughput

0.536

High

1388399

MTEF3
Transcription termination factor 3, mitochondrial

1

1

High-throughput

0.536

High

1394085

RCC1L
RCC1-like G exchanging factor-like protein

1

2

High-throughput

0.536

High

1396352

ZFR
Zinc finger RNA-binding protein

1

3

High-throughput

0.536

High

1429456

NSRP1
Nuclear speckle splicing regulatory protein 1

1

1

High-throughput

0.536

High

1429463

MOV10
Helicase MOV-10

1

5

High-throughput

0.536

High

1429470

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

3

High-throughput

0.536

High

1429471

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

2

High-throughput

0.536

High

1429477

SRRM2
Serine/arginine repetitive matrix protein 2

1

2

High-throughput

0.536

High

1429481

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

9

High-throughput

0.536

High

1121874

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

8

Small-scale

0.516

High

183511

CASC3
Protein CASC3

1

0

High-throughput

0.513

High

570974

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.513

High

1198659

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.513

High

1203612

ZN326
DBIRD complex subunit ZNF326

1

0

High-throughput

0.513

High

1291197

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

1308059

ABC3F
DNA dC->dU-editing enzyme APOBEC-3F

1

0

High-throughput

0.513

High

1311606

SUGP2
SURP and G-patch domain-containing protein 2

1

0

High-throughput

0.513

High

1346923

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.513

High

1360240

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

0

High-throughput

0.513

High

1417183

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.513

High

1429459

PININ
Pinin

1

0

High-throughput

0.513

High

1429462

NCOA5
Nuclear receptor coactivator 5

1

0

High-throughput

0.513

High

1429466

CARF
CDKN2A-interacting protein

1

0

High-throughput

0.513

High

1429467

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.513

High

1429479

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.513

High

186008

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

1366876

RND1
Rho-related GTP-binding protein Rho6

1

1

Small-scale

0.481

High

64114

CNOT1
CCR4-NOT transcription complex subunit 1

1

1

High-throughput

0.479

High

242861

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

352545

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

473066

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

17

High-throughput

0.479

High

537874

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

765870

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.479

High

794620

RBMX
RNA-binding motif protein, X chromosome

1

10

High-throughput

0.479

High

831396

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

982546

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

1089544

ILF2
Interleukin enhancer-binding factor 2

1

1

High-throughput

0.479

High

1108132

SQSTM
Sequestosome-1

1

3

High-throughput

0.479

High

1136354

EMC2
ER membrane protein complex subunit 2

1

2

High-throughput

0.479

High

1148559

SF3B4
Splicing factor 3B subunit 4

1

17

High-throughput

0.479

High

1255460

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

1314237

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

1

High-throughput

0.479

High

1315712

DND1
Dead end protein homolog 1

1

16

High-throughput

0.479

High

1340618

TDRD7
Tudor domain-containing protein 7

1

3

High-throughput

0.479

High

1350446

BICD2
Protein bicaudal D homolog 2

1

3

High-throughput

0.479

High

1364245

TOPB1
DNA topoisomerase 2-binding protein 1

1

2

High-throughput

0.479

High

1386574

OPTN
Optineurin

1

5

High-throughput

0.479

High

1405677

NECD
Necdin

1

5

High-throughput

0.479

High

1410364

MEP50
Methylosome protein WDR77

1

3

High-throughput

0.479

High

1429460

TDRD3
Tudor domain-containing protein 3

1

1

High-throughput

0.479

High

1429469

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1429473

FZR1
Fizzy-related protein homolog

1

7

High-throughput

0.479

High

1429476

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

4

High-throughput

0.479

High

1429478

LC7L2
Putative RNA-binding protein Luc7-like 2

1

1

High-throughput

0.479

High

273928

CNOT3
CCR4-NOT transcription complex subunit 3

1

0

High-throughput

0.458

High

386210

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

1106695

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1128824

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1331963

ASCC1
Activating signal cointegrator 1 complex subunit 1

1

0

High-throughput

0.458

High

1339170

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1365355

CNOT9
CCR4-NOT transcription complex subunit 9

1

0

High-throughput

0.458

High

1393675

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1429461

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.458

High

1429468

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.458

High

506144

PAB4L
Polyadenylate-binding protein 4-like

1

13

High-throughput

0.445

High

106623

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

373103

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.437

High

406625

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.437

High

696453

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

769128

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1229075

RNF43
E3 ubiquitin-protein ligase RNF43

1

1

High-throughput

0.437

High

1429457

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

1

High-throughput

0.437

High

404905

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1226263

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.426

High

1429480

PPME1
Protein phosphatase methylesterase 1

1

0

High-throughput

0.279

Low

1135507

T132D
Transmembrane protein 132D

1

0

Small-scale

0.251

Low

189822

STX7
Syntaxin-7

1

0

High-throughput

0.249

Low

338956

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.249

Low

1429475

STX8
Syntaxin-8

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025