HitPredict

Interactor 1: SRBS1 (G5EC32)
Sorbin and SH3 domain-containing protein 1 homolog
Gene: sorb-1

Interactor 2: Q19019 (Q19019)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27)
Gene: sli-1

Species: Caenorhabditis elegans

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	10615043, 19447967, 23549480
Identification Methods	two hybrid pooling approach, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1005 Ce			1 582
+	Mm
		1112057 SRBS1_MOUSE (748-1004): 5.61e-42: 169: 27.52		CBLB_MOUSE (55-448): 0: 705: 55.61
+	Hs
		235501 VINEX_HUMAN (357-1004): 2.66e-41: 164: 17.74		CBLB_HUMAN (55-448): 0: 702: 55.61
+	Mm
		610595 SRBS2_MOUSE (392-1004): 3.92e-42: 169: 17.58		CBL_MOUSE (65-523): 0: 685: 47.43
+	Mm
		610608 SRBS1_MOUSE (748-1004): 5.61e-42: 169: 27.52		CBL_MOUSE (65-523): 0: 685: 47.43
+	Hs
		298976 SRBS2_HUMAN (80-1004): 1.44e-36: 151: 14.96		CBLB_HUMAN (55-448): 0: 702: 55.61
+	Hs
		235473 VINEX_HUMAN (357-1004): 2.66e-41: 164: 17.74		CBL_HUMAN (65-448): 0: 686: 54.76
+	Dm
		112567 M9ND00_DROME (458-812): 4.23e-18: 92.1: 17.85		O46034_DROME (27-464): 0: 746: 51.80
+	Hs
		298949 SRBS2_HUMAN (80-1004): 1.44e-36: 151: 14.96		CBL_HUMAN (65-448): 0: 686: 54.76
+	Hs
		610393 SPTN1_HUMAN (456-964): 1.24e-34: 146: 13.37		CBL_HUMAN (65-448): 0: 686: 54.76
+	Mm
		1112081 ITSN2_MOUSE (142-1005): 2.49e-20: 99.8: 12.49		CBLB_MOUSE (55-448): 0: 705: 55.61
+	Hs
		1027627 ITSN2_HUMAN (143-1005): 2.89e-19: 96.3: 10.97		CBLB_HUMAN (55-448): 0: 702: 55.61
+	Mm
		292684 GRAP2_MOUSE (498-740): 1.78e-19: 92.9: 13.17		CBLB_MOUSE (55-448): 0: 705: 55.61
+	Hs
		610501 SRBS1_HUMAN (878-1003): 1.56e-20: 100: 32.54		CBL_HUMAN (65-448): 0: 686: 54.76
+	Mm
		610657 ITSN2_MOUSE (142-1005): 2.49e-20: 99.8: 12.49		CBL_MOUSE (65-523): 0: 685: 47.43
+	Hs
		610517 ITSN2_HUMAN (143-1005): 2.89e-19: 96.3: 10.97		CBL_HUMAN (65-448): 0: 686: 54.76
+	Hs
		610496 SH3G3_HUMAN (800-1003): 2.06e-20: 96: 14.22		CBL_HUMAN (65-448): 0: 686: 54.76
+	Hs
		610379 MYO1E_HUMAN (546-740): 2.69e-18: 92.9: 15.00		CBL_HUMAN (65-448): 0: 686: 54.76
+	Mm
		292681 GRAP2_MOUSE (498-740): 1.78e-19: 92.9: 13.17		CBL_MOUSE (65-523): 0: 685: 47.43
+	Hs
		610495 SH3G2_HUMAN (878-1003): 1.41e-18: 90.4: 22.22		CBL_HUMAN (65-448): 0: 686: 54.76
+	Hs
		1307462 SH3G3_HUMAN (800-1003): 2.06e-20: 96: 14.22		CBLC_HUMAN (53-515): 0: 652: 39.79