Protein: RANG
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)

Gene: RANG, RANBP1
Organism: Homo sapiens
Interactions: 210
UniProt ID: P43487

Gene Ontology (top 5):
GO:0005092 - GDP-dissociation inhibitor activity
GO:0005096 - GTPase activator activity
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849323

RAN
GTP-binding nuclear protein Ran

14

20

Small-scale

0.981

High

849306

RBP2
E3 SUMO-protein ligase RanBP2

4

17

High-throughput

0.886

High

172549

XPO1
Exportin-1

3

20

Small-scale

0.825

High

849346

IMB1
Importin subunit beta-1

8

20

Small-scale

0.750

High

616263

RCC1
Regulator of chromosome condensation

4

9

High-throughput

0.699

High

66740

RGPD3
RanBP2-like and GRIP domain-containing protein 3

1

16

High-throughput

0.691

High

849318

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.656

High

123231

PDLI1
PDZ and LIM domain protein 1

2

2

High-throughput

0.628

High

318656

RHBT1
Rho-related BTB domain-containing protein 1

1

4

High-throughput

0.618

High

375269

RASK
GTPase KRas

1

1

High-throughput

0.618

High

515814

RGPD2
RANBP2-like and GRIP domain-containing protein 2

1

17

High-throughput

0.618

High

849299

RANG
Ran-specific GTPase-activating protein

1

18

High-throughput

0.618

High

563376

CFTR
Cystic fibrosis transmembrane conductance regulator

2

5

High-throughput

0.611

High

240999

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

371404

MYC
Myc proto-oncogene protein

2

4

High-throughput

0.584

High

247725

NUPR1
Nuclear protein 1

2

1

Small-scale

0.576

High

849355

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

4

Small-scale

0.571

High

849392

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

133971

IPO5
Importin-5

1

19

High-throughput

0.536

High

138646

IMA4
Importin subunit alpha-4

1

20

High-throughput

0.536

High

142495

IMA3
Importin subunit alpha-3

1

20

High-throughput

0.536

High

164545

TNPO2
Transportin-2

1

20

High-throughput

0.536

High

189125

IPO8
Importin-8

1

16

High-throughput

0.536

High

291245

NU155
Nuclear pore complex protein Nup155

1

4

High-throughput

0.536

High

318121

IPO13
Importin-13

1

20

High-throughput

0.536

High

334705

IPO7
Importin-7

1

18

High-throughput

0.536

High

340097

PCNT
Pericentrin

1

4

High-throughput

0.536

High

385532

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.536

High

529286

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.536

High

634338

LMNB1
Lamin-B1

1

7

High-throughput

0.536

High

764517

CTNB1
Catenin beta-1

1

20

High-throughput

0.536

High

775498

NU214
Nuclear pore complex protein Nup214

1

13

High-throughput

0.536

High

789071

NUP62
Nuclear pore glycoprotein p62

1

12

High-throughput

0.536

High

849300

RAGP1
Ran GTPase-activating protein 1

1

6

High-throughput

0.536

High

849305

NU153
Nuclear pore complex protein Nup153

1

19

High-throughput

0.536

High

849309

NUP98
Nuclear pore complex protein Nup98-Nup96

1

20

High-throughput

0.536

High

849310

HIRA
Protein HIRA

1

3

High-throughput

0.536

High

849315

NU107
Nuclear pore complex protein Nup107

1

5

High-throughput

0.536

High

849320

ARP2
Actin-related protein 2

1

3

High-throughput

0.536

High

849324

SUMO1
Small ubiquitin-related modifier 1

1

7

High-throughput

0.536

High

849326

UBC9
SUMO-conjugating enzyme UBC9

1

5

High-throughput

0.536

High

849327

RAE1L
mRNA export factor RAE1

1

2

High-throughput

0.536

High

849334

NU160
Nuclear pore complex protein Nup160

1

3

High-throughput

0.536

High

849347

EEA1
Early endosome antigen 1

1

4

High-throughput

0.536

High

849353

IF16
Gamma-interferon-inducible protein 16

1

4

High-throughput

0.536

High

849364

NUP54
Nucleoporin p54

1

16

High-throughput

0.536

High

849368

PB1
Protein polybromo-1

1

5

High-throughput

0.536

High

849372

NUP93
Nuclear pore complex protein Nup93

1

2

High-throughput

0.536

High

849380

NUP43
Nucleoporin Nup43

1

8

High-throughput

0.536

High

849381

NUP37
Nucleoporin Nup37

1

3

High-throughput

0.536

High

849382

NUP35
Nucleoporin NUP35

1

3

High-throughput

0.536

High

849384

NEK7
Serine/threonine-protein kinase Nek7

1

4

High-throughput

0.536

High

849386

IPO4
Importin-4

1

20

High-throughput

0.536

High

849387

NU133
Nuclear pore complex protein Nup133

1

3

High-throughput

0.536

High

849389

NU205
Nuclear pore complex protein Nup205

1

1

High-throughput

0.536

High

849390

TNPO1
Transportin-1

1

20

High-throughput

0.536

High

849396

IPO9
Importin-9

1

16

High-throughput

0.536

High

849401

NUP85
Nuclear pore complex protein Nup85

1

4

High-throughput

0.536

High

849403

NUSAP
Nucleolar and spindle-associated protein 1

1

1

High-throughput

0.536

High

849411

MOG1
Ran guanine nucleotide release factor

1

2

High-throughput

0.536

High

849419

XPO7
Exportin-7

1

14

High-throughput

0.536

High

135540

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.513

High

192561

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

571754

FPPS
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.513

High

724923

HXA10
Homeobox protein Hox-A10

1

0

High-throughput

0.513

High

764268

CTNA1
Catenin alpha-1

1

0

High-throughput

0.513

High

787922

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

843360

HD
Huntingtin

1

0

High-throughput

0.513

High

849316

MYL6
Myosin light polypeptide 6

1

0

High-throughput

0.513

High

849317

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.513

High

849350

MTFR1
Mitochondrial fission regulator 1

1

0

High-throughput

0.513

High

849383

PHOP1
Phosphoethanolamine/phosphocholine phosphatase

1

0

High-throughput

0.513

High

849385

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.513

High

849394

SCLY
Selenocysteine lyase

1

0

High-throughput

0.513

High

849397

NUP88
Nuclear pore complex protein Nup88

1

0

High-throughput

0.513

High

849417

ARMX3
Armadillo repeat-containing X-linked protein 3

1

0

High-throughput

0.513

High

849418

FEZ2
Fasciculation and elongation protein zeta-2

1

0

High-throughput

0.513

High

849328

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.501

High

849402

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.500

High

635172

HNF1A
Hepatocyte nuclear factor 1-alpha

1

0

Small-scale

0.493

High

711611

3MG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.493

High

849405

RM01
Large ribosomal subunit protein uL1m

1

1

High-throughput

0.489

High

136844

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

3

High-throughput

0.479

High

157059

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

273498

DJC13
DnaJ homolog subfamily C member 13

1

2

High-throughput

0.479

High

315243

RECQ4
ATP-dependent DNA helicase Q4

1

4

High-throughput

0.479

High

325717

UBR5
E3 ubiquitin-protein ligase UBR5

1

2

Small-scale

0.479

High

362938

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

365326

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.479

High

536688

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

550165

PABP1
Polyadenylate-binding protein 1

1

1

High-throughput

0.479

High

555936

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

588123

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

606380

CEBPB
CCAAT/enhancer-binding protein beta

1

7

High-throughput

0.479

High

629632

BTF3
Transcription factor BTF3

1

5

High-throughput

0.479

High

669838

MCM3
DNA replication licensing factor MCM3

1

7

High-throughput

0.479

High

690813

1433T
14-3-3 protein theta

1

6

High-throughput

0.479

High

693267

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

3

High-throughput

0.479

High

694843

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

849301

MAP1B
Microtubule-associated protein 1B

1

3

High-throughput

0.479

High

849312

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

849313

SUMO3
Small ubiquitin-related modifier 3

1

7

High-throughput

0.479

High

849319

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.479

High

849322

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

849325

RACK1
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

849329

EWS
RNA-binding protein EWS

1

3

High-throughput

0.479

High

849335

ANK3
Ankyrin-3

1

1

High-throughput

0.479

High

849336

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

2

High-throughput

0.479

High

849338

RFA4
Replication protein A 30 kDa subunit

1

5

High-throughput

0.479

High

849339

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.479

High

849341

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

849342

CUL3
Cullin-3

1

5

High-throughput

0.479

High

849344

TRI14
Tripartite motif-containing protein 14

1

3

High-throughput

0.479

High

849345

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

5

High-throughput

0.479

High

849351

SF01
Splicing factor 1

1

1

High-throughput

0.479

High

849352

EZH2
Histone-lysine N-methyltransferase EZH2

1

6

High-throughput

0.479

High

849357

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

1

High-throughput

0.479

High

849358

IFIX
Pyrin and HIN domain-containing protein 1

1

4

High-throughput

0.479

High

849360

PLBL1
Phospholipase B-like 1

1

1

High-throughput

0.479

High

849362

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

849365

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

849369

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

849373

RHG24
Rho GTPase-activating protein 24

1

1

High-throughput

0.479

High

849375

WDTC1
WD and tetratricopeptide repeats protein 1

1

3

High-throughput

0.479

High

849377

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

849388

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

849391

FBXW7
F-box/WD repeat-containing protein 7

1

3

Small-scale

0.479

High

849400

NUP58
Nucleoporin p58/p45

1

10

High-throughput

0.479

High

849406

WWTR1
WW domain-containing transcription regulator protein 1

1

2

High-throughput

0.479

High

849409

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.479

High

849410

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

849413

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

1

High-throughput

0.479

High

849414

DUX4
Double homeobox protein 4

1

4

High-throughput

0.479

High

849416

ZRAN1
Ubiquitin thioesterase ZRANB1

1

20

High-throughput

0.479

High

849420

HERC5
E3 ISG15--protein ligase HERC5

1

1

Small-scale

0.479

High

849421

TNIK
TRAF2 and NCK-interacting protein kinase

1

3

High-throughput

0.479

High

849422

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

2

High-throughput

0.479

High

849423

NINL
Ninein-like protein

1

1

High-throughput

0.479

High

849424

T22D4
TSC22 domain family protein 4

1

1

High-throughput

0.479

High

849425

TRAF6
TNF receptor-associated factor 6

1

4

High-throughput

0.479

High

849426

TRI17
E3 ubiquitin-protein ligase TRIM17

1

3

Small-scale

0.479

High

849427

YTHD2
YTH domain-containing family protein 2

1

2

High-throughput

0.479

High

319495

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

332906

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

0

High-throughput

0.458

High

377081

PENK
Proenkephalin-A [Cleaved into: Synenkephalin; Met-enkephalin

1

0

High-throughput

0.458

High

538901

EPB41
Protein 4.1

1

0

High-throughput

0.458

High

640800

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

High-throughput

0.458

High

659392

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

659988

COF1
Cofilin-1

1

0

High-throughput

0.458

High

791158

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

822507

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

849307

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.458

High

849308

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

High-throughput

0.458

High

849311

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

849331

RON
Macrophage-stimulating protein receptor

1

0

High-throughput

0.458

High

849332

ACTN3
Alpha-actinin-3

1

0

High-throughput

0.458

High

849333

LMOD3
Leiomodin-3

1

0

High-throughput

0.458

High

849337

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

849349

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.458

High

849356

DDI2
Protein DDI1 homolog 2

1

0

High-throughput

0.458

High

849363

BCAP
Phosphoinositide 3-kinase adapter protein 1

1

0

High-throughput

0.458

High

849367

DPPA2
Developmental pluripotency-associated protein 2

1

0

High-throughput

0.458

High

849378

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

849393

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

849398

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

849399

DPYL5
Dihydropyrimidinase-related protein 5

1

0

High-throughput

0.458

High

849407

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

849415

TRM7
tRNA

1

0

High-throughput

0.458

High

166266

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.445

High

171410

S27A2
Long-chain fatty acid transport protein 2

1

3

High-throughput

0.445

High

429472

JUN
Transcription factor Jun

1

6

High-throughput

0.445

High

849314

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.445

High

849321

SUMO2
Small ubiquitin-related modifier 2

1

7

High-throughput

0.445

High

849354

Q5JRG1
Nucleoporin 58

1

11

High-throughput

0.445

High

849395

CEP63
Centrosomal protein of 63 kDa

1

8

High-throughput

0.445

High

192462

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.437

High

217935

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

219763

KCNQ3
Potassium voltage-gated channel subfamily KQT member 3

1

3

High-throughput

0.437

High

411534

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.437

High

767618

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

849302

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.437

High

849348

P2RY6
P2Y purinoceptor 6

1

2

High-throughput

0.437

High

849370

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.437

High

849374

EMC5
ER membrane protein complex subunit 5

1

1

High-throughput

0.437

High

849376

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.437

High

849408

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.437

High

849412

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

4

High-throughput

0.437

High

849428

INSI2
Insulin-induced gene 2 protein

1

1

High-throughput

0.437

High

849330

TAGL
Transgelin

1

0

High-throughput

0.426

High

849371

LACC1
Purine nucleoside phosphorylase LACC1

1

0

Small-scale

0.426

High

849303

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

High-throughput

0.408

High

849361

S27A1
Long-chain fatty acid transport protein 1

1

3

High-throughput

0.407

High

619586

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.298

High

299101

FLOT1
Flotillin-1

1

0

High-throughput

0.279

Low

773819

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

849340

TUSC3
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3

1

0

High-throughput

0.279

Low

849343

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.279

Low

849366

RM10
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.279

Low

849404

RM09
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.279

Low

254552

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

377188

SOMA
Somatotropin

1

0

High-throughput

0.249

Low

379931

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

389130

FINC
Fibronectin

1

0

High-throughput

0.249

Low

469024

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.249

Low

590830

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.249

Low

683195

CO5A3

1

0

High-throughput

0.249

Low

849304

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

849359

RM54
Large ribosomal subunit protein mL54

1

0

High-throughput

0.249

Low

849379

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025