HitPredict

Interactor 1: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Interactor 2: PTPRU (Q92729)
Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase J) (PTP-J) (hPTP-J) (Protein-tyrosine phosphatase pi) (PTP pi) (Protein-tyrosine phosphatase receptor omicron) (PTP-RO) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi)
Gene: PTPRU

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2221 Hs			1 1446
+	Hs
		577021 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PTPRA_HUMAN (673-1443): 0: 755: 28.46
+	Hs
		617111 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PTPRG_HUMAN (295-1445): 0: 670: 21.71
+	Hs
		489959 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PTPRF_HUMAN (7-941): 1.88e-67: 254: 11.64
+	Hs
		616972 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PTPRD_HUMAN (187-963): 3.95e-39: 162: 10.28
+	Hs
		1031981 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		PTPRS_HUMAN (187-943): 1.73e-38: 160: 10.32
+	Rn
		388054 SCN1A_RAT (1221-1814): 1.42e-15: 85.8: 12.44		PTPRZ_RAT (891-1159): 1.27e-44: 180: 25.00
+	Hs
		1032019 SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45		PTPRS_HUMAN (187-943): 1.73e-38: 160: 10.32