Protein: RPB1
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)

Gene: RPB1, POLR2A
Organism: Homo sapiens
Interactions: 460
UniProt ID: P24928

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0003968 - RNA-directed RNA polymerase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

130379

SPT5H
Transcription elongation factor SPT5

11

4

Small-scale

0.978

High

667253

RPB7
DNA-directed RNA polymerase II subunit RPB7

11

12

Small-scale

0.977

High

667471

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

7

17

Small-scale

0.968

High

621813

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

7

15

Small-scale

0.968

High

192787

RPB4
DNA-directed RNA polymerase II subunit RPB4

7

8

Small-scale

0.967

High

654613

TCEA1
Transcription elongation factor A protein 1

8

8

Small-scale

0.965

High

667226

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

8

10

Small-scale

0.964

High

667194

T2FA
General transcription factor IIF subunit 1

7

1

Small-scale

0.963

High

621557

RPB3
DNA-directed RNA polymerase II subunit RPB3

7

19

Small-scale

0.962

High

667227

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

7

11

Small-scale

0.960

High

667244

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

6

10

Small-scale

0.950

High

667277

ERCC6
DNA excision repair protein ERCC-6

6

12

Small-scale

0.928

High

667184

RPB2
DNA-directed RNA polymerase II subunit RPB2

5

20

Small-scale

0.918

High

667363

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

4

3

Small-scale

0.899

High

667197

RPB9
DNA-directed RNA polymerase II subunit RPB9

4

20

Small-scale

0.890

High

667230

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

4

9

Small-scale

0.890

High

667271

TF2B
Transcription initiation factor IIB

3

5

Small-scale

0.866

High

667219

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

4

8

Small-scale

0.860

High

667353

SPT6H
Transcription elongation factor SPT6

3

5

Small-scale

0.834

High

622754

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

3

8

Small-scale

0.827

High

667430

MED18
Mediator of RNA polymerase II transcription subunit 18

3

0

High-throughput

0.827

High

667415

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

15

Small-scale

0.811

High

667180

T2EA
General transcription factor IIE subunit 1

2

1

Small-scale

0.806

High

667276

KMT2A
Histone-lysine N-methyltransferase 2A

2

11

Small-scale

0.806

High

667435

SETD2
Histone-lysine N-methyltransferase SETD2

2

9

Small-scale

0.806

High

262480

MCE1
mRNA-capping enzyme

2

7

High-throughput

0.789

High

287765

MED6
Mediator of RNA polymerase II transcription subunit 6

2

3

High-throughput

0.789

High

667442

XRN2
5'-3' exoribonuclease 2

2

1

Small-scale

0.789

High

667522

MED31
Mediator of RNA polymerase II transcription subunit 31

2

0

High-throughput

0.770

High

667217

CDK9
Cyclin-dependent kinase 9

24

12

Small-scale

0.767

High

667216

CDK7
Cyclin-dependent kinase 7

12

8

Small-scale

0.759

High

667200

BRCA1
Breast cancer type 1 susceptibility protein

12

4

Small-scale

0.757

High

316254

RECQ5
ATP-dependent DNA helicase Q5

8

10

Small-scale

0.753

High

667476

MED17
Mediator of RNA polymerase II transcription subunit 17

2

0

High-throughput

0.748

High

667482

PIHD1
PIH1 domain-containing protein 1

7

3

Small-scale

0.745

High

667524

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

6

7

Small-scale

0.738

High

667208

CDK8
Cyclin-dependent kinase 8

6

11

Small-scale

0.727

High

667411

NSD1
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

12

Small-scale

0.724

High

48907

MED19
Mediator of RNA polymerase II transcription subunit 19

7

0

High-throughput

0.718

High

667327

UVSSA
UV-stimulated scaffold protein A

2

0

Small-scale

0.716

High

667218

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

2

8

Small-scale

0.712

High

667370

PAF1
RNA polymerase II-associated factor 1 homolog

5

2

Small-scale

0.711

High

667257

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

5

11

Small-scale

0.709

High

316352

RMP
Unconventional prefoldin RPB5 interactor 1

5

3

Small-scale

0.706

High

667294

MED21
Mediator of RNA polymerase II transcription subunit 21

6

0

Small-scale

0.702

High

667495

UXT
Protein UXT

4

2

High-throughput

0.699

High

628699

TBP
TATA-box-binding protein

4

4

Small-scale

0.698

High

667176

IKBA
NF-kappa-B inhibitor alpha

4

1

Small-scale

0.697

High

219472

MED7
Mediator of RNA polymerase II transcription subunit 7

1

3

High-throughput

0.691

High

413213

P53
Cellular tumor antigen p53

1

0

Small-scale

0.687

High

667447

MED28
Mediator of RNA polymerase II transcription subunit 28

5

0

High-throughput

0.684

High

667289

ERCC8
DNA excision repair protein ERCC-8

4

5

Small-scale

0.680

High

667340

CDC73
Parafibromin

4

2

Small-scale

0.680

High

395511

ESR1
Estrogen receptor

4

5

Small-scale

0.676

High

667207

YAP1
Transcriptional coactivator YAP1

4

17

Small-scale

0.676

High

667279

DHX9
ATP-dependent RNA helicase A

4

2

Small-scale

0.676

High

667186

TF2H1
General transcription factor IIH subunit 1

5

0

Small-scale

0.674

High

667206

NEDD4
E3 ubiquitin-protein ligase NEDD4

3

11

Small-scale

0.667

High

131738

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

3

9

High-throughput

0.667

High

667285

CSTF3
Cleavage stimulation factor subunit 3

3

5

Small-scale

0.664

High

667273

HNRPU
Heterogeneous nuclear ribonucleoprotein U

3

3

Small-scale

0.664

High

667290

TIF1B
Transcription intermediary factor 1-beta

3

2

Small-scale

0.664

High

667481

MED9
Mediator of RNA polymerase II transcription subunit 9

4

0

High-throughput

0.664

High

608455

DDX5
Probable ATP-dependent RNA helicase DDX5

3

3

Small-scale

0.662

High

667201

VHL
von Hippel-Lindau disease tumor suppressor

4

0

Small-scale

0.656

High

259458

BRD4
Bromodomain-containing protein 4

3

11

High-throughput

0.656

High

371192

MYC
Myc proto-oncogene protein

3

4

High-throughput

0.656

High

667313

MED1
Mediator of RNA polymerase II transcription subunit 1

3

3

Small-scale

0.656

High

667466

GPN1
GPN-loop GTPase 1

3

9

High-throughput

0.656

High

667278

CSTF1
Cleavage stimulation factor subunit 1

3

5

Small-scale

0.651

High

505997

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

4

1

High-throughput

0.650

High

667343

CTR9
RNA polymerase-associated protein CTR9 homolog

3

1

Small-scale

0.650

High

161411

KMT2D
Histone-lysine N-methyltransferase 2D

1

15

Small-scale

0.647

High

667173

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

11

Small-scale

0.647

High

550849

PCNA
Proliferating cell nuclear antigen

3

1

Small-scale

0.640

High

615480

NELFE
Negative elongation factor E

3

1

Small-scale

0.640

High

667281

EP300
Histone acetyltransferase p300

3

7

Small-scale

0.640

High

667299

CUL3
Cullin-3

3

3

High-throughput

0.640

High

667211

CTCF
Transcriptional repressor CTCF

2

1

Small-scale

0.639

High

667262

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

2

5

Small-scale

0.639

High

667451

CAPAM
mRNA

2

1

Small-scale

0.639

High

335958

MED26
Mediator of RNA polymerase II transcription subunit 26

3

0

High-throughput

0.638

High

667429

MED10
Mediator of RNA polymerase II transcription subunit 10

3

0

High-throughput

0.638

High

667242

ACTB
Actin, cytoplasmic 1

3

0

Small-scale

0.636

High

667265

CSK21
Casein kinase II subunit alpha

3

10

Small-scale

0.635

High

667344

WDR82
WD repeat-containing protein 82

3

10

Small-scale

0.631

High

667501

GPN3
GPN-loop GTPase 3

4

9

High-throughput

0.630

High

667280

SSRP1
FACT complex subunit SSRP1

2

11

Small-scale

0.628

High

667458

MED20
Mediator of RNA polymerase II transcription subunit 20

3

0

High-throughput

0.628

High

667470

MED4
Mediator of RNA polymerase II transcription subunit 4

3

0

High-throughput

0.628

High

163707

TCRG1
Transcription elongation regulator 1

2

7

Small-scale

0.624

High

667179

ERCC5
DNA excision repair protein ERCC-5

2

1

Small-scale

0.624

High

667388

KAT2B
Histone acetyltransferase KAT2B

2

8

Small-scale

0.624

High

667408

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

11

High-throughput

0.624

High

667449

NELFA
Negative elongation factor A

2

1

Small-scale

0.624

High

128784

MEN1
Menin

3

0

Small-scale

0.619

High

667456

TDRD3
Tudor domain-containing protein 3

2

0

Small-scale

0.618

High

165012

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

11

High-throughput

0.618

High

175839

SET1A
Histone-lysine N-methyltransferase SETD1A

1

10

Small-scale

0.618

High

180237

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

19

High-throughput

0.618

High

287439

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

4

High-throughput

0.618

High

321822

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

2

Small-scale

0.618

High

326301

SCAF4
SR-related and CTD-associated factor 4

1

6

High-throughput

0.618

High

339940

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

11

High-throughput

0.618

High

667240

ELOF1
Transcription elongation factor 1 homolog

1

1

Small-scale

0.618

High

667316

EZH2
Histone-lysine N-methyltransferase EZH2

1

13

Small-scale

0.618

High

667333

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

10

High-throughput

0.618

High

667438

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

3

High-throughput

0.618

High

667455

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

2

Small-scale

0.618

High

667461

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

20

High-throughput

0.618

High

667465

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

4

Small-scale

0.618

High

667480

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

20

High-throughput

0.618

High

667489

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

20

High-throughput

0.618

High

667513

SET1B
Histone-lysine N-methyltransferase SETD1B

1

12

Small-scale

0.618

High

667523

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

12

High-throughput

0.618

High

667337

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

4

2

High-throughput

0.617

High

239539

MED14
Mediator of RNA polymerase II transcription subunit 14

2

7

High-throughput

0.611

High

477918

SNRPA
U1 small nuclear ribonucleoprotein A

2

4

High-throughput

0.611

High

667195

FUS
RNA-binding protein FUS

2

9

High-throughput

0.611

High

667298

CUL2
Cullin-2

2

3

High-throughput

0.611

High

667392

CUL5
Cullin-5

2

3

High-throughput

0.611

High

667399

ARMC5
Armadillo repeat-containing protein 5

2

3

High-throughput

0.611

High

667519

RUVB2
RuvB-like 2

2

9

High-throughput

0.611

High

667487

WWOX
WW domain-containing oxidoreductase

2

1

High-throughput

0.608

High

667223

CCNH
Cyclin-H

2

5

Small-scale

0.602

High

667282

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

2

3

Small-scale

0.602

High

667175

RBTN2
Rhombotin-2

2

0

High-throughput

0.602

High

667402

CPNE2
Copine-2

2

0

High-throughput

0.602

High

667422

INT14
Integrator complex subunit 14

2

0

High-throughput

0.602

High

667484

MED29
Mediator of RNA polymerase II transcription subunit 29

2

0

High-throughput

0.602

High

667467

SYF1
Pre-mRNA-splicing factor SYF1

2

6

Small-scale

0.601

High

162473

ANM5
Protein arginine N-methyltransferase 5

1

2

Small-scale

0.597

High

667303

ELOA1
Elongin-A

2

2

Small-scale

0.595

High

667425

BARD1
BRCA1-associated RING domain protein 1

2

2

Small-scale

0.595

High

296959

CCNK
Cyclin-K

2

5

Small-scale

0.594

High

667312

TAF11
Transcription initiation factor TFIID subunit 11

2

0

Small-scale

0.592

High

480034

RU1C
U1 small nuclear ribonucleoprotein C

2

0

High-throughput

0.585

High

574146

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

0

High-throughput

0.585

High

667341

MED27
Mediator of RNA polymerase II transcription subunit 27

2

0

High-throughput

0.585

High

667403

MED8
Mediator of RNA polymerase II transcription subunit 8

2

0

High-throughput

0.585

High

667407

MED30
Mediator of RNA polymerase II transcription subunit 30

2

0

Small-scale

0.585

High

667488

MED11
Mediator of RNA polymerase II transcription subunit 11

2

0

High-throughput

0.585

High

667380

LEO1
RNA polymerase-associated protein LEO1

2

2

Small-scale

0.585

High

667503

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

2

4

Small-scale

0.585

High

667453

RPAP3
RNA polymerase II-associated protein 3

3

6

High-throughput

0.585

High

130701

TAF4
Transcription initiation factor TFIID subunit 4

2

3

Small-scale

0.584

High

591482

H2AX
Histone H2AX

2

6

Small-scale

0.584

High

606242

CEBPB
CCAAT/enhancer-binding protein beta

2

2

Small-scale

0.584

High

667178

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

3

Small-scale

0.584

High

667235

TERA
Transitional endoplasmic reticulum ATPase

2

4

Small-scale

0.584

High

667254

H4
Histone H4

2

4

High-throughput

0.584

High

667258

RBX1
E3 ubiquitin-protein ligase RBX1

2

1

Small-scale

0.584

High

667288

CBX3
Chromobox protein homolog 3

2

3

Small-scale

0.584

High

667318

DDB1
DNA damage-binding protein 1

2

3

Small-scale

0.584

High

667386

CBP
CREB-binding protein

2

6

Small-scale

0.584

High

667490

PHRF1
PHD and RING finger domain-containing protein 1

2

3

Small-scale

0.584

High

667505

INT6
Integrator complex subunit 6

2

1

Small-scale

0.584

High

667506

AGO1
Protein argonaute-1

2

6

Small-scale

0.584

High

667322

SMN
Survival motor neuron protein

1

0

Small-scale

0.583

High

667224

MAT1
CDK-activating kinase assembly factor MAT1

2

0

Small-scale

0.577

High

193502

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

4

High-throughput

0.571

High

569055

T2FB
General transcription factor IIF subunit 2

2

2

Small-scale

0.571

High

667190

MCM7
DNA replication licensing factor MCM7

2

2

Small-scale

0.571

High

667212

MCM2
DNA replication licensing factor MCM2

2

3

Small-scale

0.571

High

667292

ATM
Serine-protein kinase ATM

2

0

Small-scale

0.569

High

667305

MDC1
Mediator of DNA damage checkpoint protein 1

2

2

Small-scale

0.563

High

667187

CSTF2
Cleavage stimulation factor subunit 2

1

4

Small-scale

0.561

High

667287

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

3

Small-scale

0.561

High

667291

SKP2
S-phase kinase-associated protein 2

1

1

High-throughput

0.561

High

667428

WAC
WW domain-containing adapter protein with coiled-coil

1

1

Small-scale

0.561

High

667512

PHF8
Histone lysine demethylase PHF8

1

5

Small-scale

0.561

High

667307

CUL7
Cullin-7

2

0

High-throughput

0.559

High

667314

TRIP4
Activating signal cointegrator 1

2

0

High-throughput

0.559

High

667355

SETX
Probable helicase senataxin

1

5

Small-scale

0.554

High

667468

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

2

Small-scale

0.550

High

667409

NEUL4
Neuralized-like protein 4

2

0

Small-scale

0.547

High

257225

PQBP1
Polyglutamine-binding protein 1

1

0

Small-scale

0.537

High

540811

ERG
Transcriptional regulator ERG

1

0

Small-scale

0.537

High

559223

XRCC5
X-ray repair cross-complementing protein 5

1

0

Small-scale

0.537

High

595947

H12
Histone H1.2

1

0

Small-scale

0.537

High

667319

ZNF74
Zinc finger protein 74

1

0

Small-scale

0.537

High

667354

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

Small-scale

0.537

High

667404

OTUD5
OTU domain-containing protein 5

1

0

Small-scale

0.537

High

193086

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

3

High-throughput

0.536

High

481096

HMGB1
High mobility group protein B1

1

9

High-throughput

0.536

High

667236

NH2L1
NHP2-like protein 1

1

2

High-throughput

0.536

High

667249

RUXF
Small nuclear ribonucleoprotein F

1

2

High-throughput

0.536

High

667268

SRPK2
SRSF protein kinase 2

1

5

High-throughput

0.536

High

667309

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

667320

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

8

High-throughput

0.536

High

667323

MK06
Mitogen-activated protein kinase 6

1

6

High-throughput

0.536

High

667325

H2B2E
Histone H2B type 2-E

1

11

High-throughput

0.536

High

667329

ZN326
DBIRD complex subunit ZNF326

1

1

Small-scale

0.536

High

667368

ARRD1
Arrestin domain-containing protein 1

1

6

High-throughput

0.536

High

667400

HDA11
Histone deacetylase 11

1

2

High-throughput

0.536

High

667413

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.536

High

667423

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.536

High

667426

EPAS1
Endothelial PAS domain-containing protein 1

1

1

High-throughput

0.536

High

667443

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

11

High-throughput

0.536

High

667446

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

2

High-throughput

0.536

High

667448

TXNIP
Thioredoxin-interacting protein

1

6

High-throughput

0.536

High

667459

WDR76
WD repeat-containing protein 76

1

8

High-throughput

0.536

High

667414

DAA10
Dynein axonemal assembly factor 10

2

2

High-throughput

0.533

High

667283

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

2

0

Small-scale

0.528

High

667385

TF2H4
General transcription factor IIH subunit 4

1

0

Small-scale

0.527

High

667367

SH2D3
SH2 domain-containing protein 3C

2

4

High-throughput

0.521

High

327549

ELP1
Elongator complex protein 1

1

1

Small-scale

0.515

High

667498

ZNHI2
Zinc finger HIT domain-containing protein 2

1

1

High-throughput

0.515

High

216627

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

541836

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

593022

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.513

High

601564

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

667210

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

667269

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

667352

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.513

High

667361

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

667397

SOSB2
SOSS complex subunit B2

1

0

High-throughput

0.513

High

667405

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

667261

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.508

High

158552

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

7

Small-scale

0.501

High

251516

CCNT1
Cyclin-T1

1

5

Small-scale

0.501

High

543459

VDR
Vitamin D3 receptor

1

4

Small-scale

0.501

High

667177

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

Small-scale

0.501

High

667188

TTK
Dual specificity protein kinase TTK

1

1

Small-scale

0.501

High

667241

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

High-throughput

0.501

High

667245

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.501

High

667247

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

8

Small-scale

0.501

High

667264

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

2

Small-scale

0.501

High

667310

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

4

Small-scale

0.501

High

667421

IWS1
Protein IWS1 homolog

1

2

Small-scale

0.501

High

667440

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

7

Small-scale

0.501

High

667464

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

11

Small-scale

0.501

High

667491

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

2

Small-scale

0.501

High

667492

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

4

Small-scale

0.501

High

667510

PRP19
Pre-mRNA-processing factor 19

1

4

Small-scale

0.501

High

667511

CC14A
Dual specificity protein phosphatase CDC14A

1

5

Small-scale

0.501

High

667485

CDK12
Cyclin-dependent kinase 12

1

12

Small-scale

0.500

High

667515

DICER
Endoribonuclease Dicer

1

5

Small-scale

0.500

High

667406

SNF8
Vacuolar-sorting protein SNF8

1

0

Small-scale

0.493

High

667365

MIER1
Mesoderm induction early response protein 1

1

0

High-throughput

0.493

High

667379

THAP3
THAP domain-containing protein 3

1

0

High-throughput

0.493

High

667301

DPYL1
Dihydropyrimidinase-related protein 1

1

2

High-throughput

0.489

High

667302

DPYL3
Dihydropyrimidinase-related protein 3

1

2

High-throughput

0.489

High

667373

ARRD4
Arrestin domain-containing protein 4

1

6

High-throughput

0.489

High

667378

ARRD2
Arrestin domain-containing protein 2

1

6

High-throughput

0.489

High

667398

ARRD3
Arrestin domain-containing protein 3

1

6

High-throughput

0.489

High

667401

RMC1
Regulator of MON1-CCZ1 complex

1

1

High-throughput

0.489

High

667420

TCPQM
T-complex protein 1 subunit theta-like 2

1

1

High-throughput

0.489

High

667496

FBLN5
Fibulin-5

1

2

High-throughput

0.489

High

667231

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

Small-scale

0.480

High

156971

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

163612

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

7

Small-scale

0.479

High

190821

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

225254

HTSF1
17S U2 SnRNP complex component HTATSF1

1

8

Small-scale

0.479

High

231106

AIRE
Autoimmune regulator

1

4

Small-scale

0.479

High

240785

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

247231

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.479

High

256775

H2B1K
Histone H2B type 1-K

1

11

High-throughput

0.479

High

281174

CDC45
Cell division control protein 45 homolog

1

1

Small-scale

0.479

High

283432

TAD2A
Transcriptional adapter 2-alpha

1

4

High-throughput

0.479

High

285084

EED
Polycomb protein EED

1

5

High-throughput

0.479

High

315132

RECQ4
ATP-dependent DNA helicase Q4

1

11

High-throughput

0.479

High

362791

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

411376

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

430606

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

3

High-throughput

0.479

High

449680

H2B1J
Histone H2B type 1-J

1

11

High-throughput

0.479

High

472462

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

7

High-throughput

0.479

High

552132

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.479

High

587944

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

637843

NF1
Neurofibromin

1

1

Small-scale

0.479

High

654089

XPA
DNA repair protein complementing XP-A cells

1

2

Small-scale

0.479

High

666796

CCNC
Cyclin-C

1

5

High-throughput

0.479

High

667174

MCM3
DNA replication licensing factor MCM3

1

3

Small-scale

0.479

High

667181

T2EB
Transcription initiation factor IIE subunit beta

1

2

Small-scale

0.479

High

667185

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

667189

MCM5
DNA replication licensing factor MCM5

1

2

Small-scale

0.479

High

667191

CTNB1
Catenin beta-1

1

2

High-throughput

0.479

High

667193

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

667196

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

High-throughput

0.479

High

667198

SRBP1
Sterol regulatory element-binding protein 1

1

3

Small-scale

0.479

High

667202

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

667204

RAD52
DNA repair protein RAD52 homolog

1

1

Small-scale

0.479

High

667209

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

4

High-throughput

0.479

High

667213

DNLI3
DNA ligase 3

1

1

Small-scale

0.479

High

667215

MRE11
Double-strand break repair protein MRE11

1

1

Small-scale

0.479

High

667221

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

667225

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.479

High

667229

ZN131
Zinc finger protein 131

1

1

High-throughput

0.479

High

667232

HIRA
Protein HIRA

1

3

Small-scale

0.479

High

667234

HAP1
Huntingtin-associated protein 1

1

1

Small-scale

0.479

High

667237

CTBP2
C-terminal-binding protein 2

1

2

High-throughput

0.479

High

667239

H2B1D
Histone H2B type 1-D

1

11

High-throughput

0.479

High

667248

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

667250

SMD1
Small nuclear ribonucleoprotein Sm D1

1

2

High-throughput

0.479

High

667252

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.479

High

667255

H2B1C
Histone H2B type 1-C/E/F/G/I

1

11

High-throughput

0.479

High

667260

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.479

High

667263

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.479

High

667266

H31
Histone H3.1

1

6

High-throughput

0.479

High

667274

EWS
RNA-binding protein EWS

1

5

Small-scale

0.479

High

667275

ENL
Protein ENL

1

3

Small-scale

0.479

High

667284

TAF10
Transcription initiation factor TFIID subunit 10

1

1

Small-scale

0.479

High

667293

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

667295

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

Small-scale

0.479

High

667297

CUL1
Cullin-1

1

3

High-throughput

0.479

High

667300

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

3

Small-scale

0.479

High

667304

RBM39
RNA-binding protein 39

1

3

High-throughput

0.479

High

667306

SMC1A
Structural maintenance of chromosomes protein 1A

1

2

Small-scale

0.479

High

667308

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

667324

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

667332

INT11
Integrator complex subunit 11

1

4

Small-scale

0.479

High

667334

RN123
E3 ubiquitin-protein ligase RNF123

1

3

High-throughput

0.479

High

667338

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

667345

MCAF1
Activating transcription factor 7-interacting protein 1

1

2

Small-scale

0.479

High

667347

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

667351

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

1

High-throughput

0.479

High

667356

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

11

High-throughput

0.479

High

667357

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

3

High-throughput

0.479

High

667359

THOC4
THO complex subunit 4

1

3

Small-scale

0.479

High

667364

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

667369

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.479

High

667374

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

667382

PSPC1
Paraspeckle component 1

1

3

High-throughput

0.479

High

667387

RBP56
TATA-binding protein-associated factor 2N

1

5

Small-scale

0.479

High

667389

DDX17
Probable ATP-dependent RNA helicase DDX17

1

3

High-throughput

0.479

High

667390

RAD50
DNA repair protein RAD50

1

4

Small-scale

0.479

High

667393

MED12
Mediator of RNA polymerase II transcription subunit 12

1

1

High-throughput

0.479

High

667394

H2B1H
Histone H2B type 1-H

1

11

High-throughput

0.479

High

667395

FBXW7
F-box/WD repeat-containing protein 7

1

5

High-throughput

0.479

High

667410

EGLN2
Prolyl hydroxylase EGLN2

1

3

Small-scale

0.479

High

667412

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

667417

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

667419

CCNL2
Cyclin-L2

1

5

Small-scale

0.479

High

667427

H2B1L
Histone H2B type 1-L

1

9

High-throughput

0.479

High

667432

CDK19
Cyclin-dependent kinase 19

1

12

High-throughput

0.479

High

667439

EGLN1
Egl nine homolog 1

1

3

Small-scale

0.479

High

667441

WWTR1
WW domain-containing transcription regulator protein 1

1

13

High-throughput

0.479

High

667445

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

667454

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

667457

SFR19
Splicing factor, arginine/serine-rich 19

1

2

High-throughput

0.479

High

667469

UBN1
Ubinuclein-1

1

1

Small-scale

0.479

High

667473

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

667478

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

3

High-throughput

0.479

High

667494

DNM3B
DNA

1

2

Small-scale

0.479

High

667497

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

667499

MED13
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.479

High

667500

PFD2
Prefoldin subunit 2

1

3

High-throughput

0.479

High

667502

BAZ1B
Tyrosine-protein kinase BAZ1B

1

12

Small-scale

0.479

High

667504

AGO2
Protein argonaute-2

1

6

Small-scale

0.479

High

667509

MYO6
Unconventional myosin-VI

1

2

Small-scale

0.479

High

667516

SMC3
Structural maintenance of chromosomes protein 3

1

2

Small-scale

0.479

High

667521

FBW1A
F-box/WD repeat-containing protein 1A

1

5

High-throughput

0.479

High

667525

CABIN
Calcineurin-binding protein cabin-1

1

2

Small-scale

0.479

High

667526

DNM3A
DNA

1

1

Small-scale

0.479

High

155079

SOCS2
Suppressor of cytokine signaling 2

1

5

High-throughput

0.470

High

156006

SOCS6
Suppressor of cytokine signaling 6

1

5

High-throughput

0.470

High

667472

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

63958

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

Small-scale

0.458

High

172485

XPO1
Exportin-1

1

0

High-throughput

0.458

High

221529

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.458

High

222731

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

228176

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

Small-scale

0.458

High

293219

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

342108

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

376712

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

424356

HMGN1
Non-histone chromosomal protein HMG-14

1

0

Small-scale

0.458

High

464359

ERCC1
DNA excision repair protein ERCC-1

1

0

Small-scale

0.458

High

611641

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

0

Small-scale

0.458

High

667182

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

0

Small-scale

0.458

High

667183

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.458

High

667192

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

667199

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

667203

HD
Huntingtin

1

0

Small-scale

0.458

High

667205

MAGAB
Melanoma-associated antigen 11

1

0

Small-scale

0.458

High

667214

CDN1C
Cyclin-dependent kinase inhibitor 1C

1

0

Small-scale

0.458

High

667220

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

667233

ATX3
Ataxin-3

1

0

Small-scale

0.458

High

667246

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

Small-scale

0.458

High

667251

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

667267

GTF2I
General transcription factor II-I

1

0

Small-scale

0.458

High

667270

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.458

High

667272

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

667286

CSN1
COP9 signalosome complex subunit 1

1

0

Small-scale

0.458

High

667311

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.458

High

667317

E2F4
Transcription factor E2F4

1

0

Small-scale

0.458

High

667321

TAZ
Tafazzin

1

0

Small-scale

0.458

High

667331

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

0

High-throughput

0.458

High

667336

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

667339

TECT3
Tectonic-3

1

0

High-throughput

0.458

High

667342

INT5
Integrator complex subunit 5

1

0

High-throughput

0.458

High

667346

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

1

0

Small-scale

0.458

High

667358

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

667366

INT1
Integrator complex subunit 1

1

0

High-throughput

0.458

High

667371

SCAI
Protein SCAI

1

0

Small-scale

0.458

High

667376

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

667377

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

667381

NELFB
Negative elongation factor B

1

0

Small-scale

0.458

High

667391

XPF
DNA repair endonuclease XPF

1

0

Small-scale

0.458

High

667396

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

667416

QKI
KH domain-containing RNA-binding protein QKI

1

0

High-throughput

0.458

High

667418

WRIP1
ATPase WRNIP1

1

0

Small-scale

0.458

High

667424

PNKP
Bifunctional polynucleotide phosphatase/kinase

1

0

Small-scale

0.458

High

667431

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

667434

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

667436

IN80B
INO80 complex subunit B

1

0

High-throughput

0.458

High

667452

STN1
CST complex subunit STN1

1

0

High-throughput

0.458

High

667477

INT10
Integrator complex subunit 10

1

0

Small-scale

0.458

High

667493

MBD2
Methyl-CpG-binding domain protein 2

1

0

Small-scale

0.458

High

667507

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

667518

RTRAF
RNA transcription, translation and transport factor protein

1

0

Small-scale

0.458

High

667527

NS1BP
Influenza virus NS1A-binding protein

1

0

Small-scale

0.458

High

505940

MYZAP
Myocardial zonula adherens protein

1

3

High-throughput

0.445

High

667228

T2AG
Transcription initiation factor IIA subunit 2

1

1

Small-scale

0.445

High

667383

RTF1
RNA polymerase-associated protein RTF1 homolog

1

1

Small-scale

0.445

High

667444

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.445

High

667462

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.445

High

667475

S39A9
Zinc transporter ZIP9

1

4

High-throughput

0.445

High

667508

AKP8L
A-kinase anchor protein 8-like

1

1

High-throughput

0.445

High

271903

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.437

High

597339

GBB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

1

6

Small-scale

0.437

High

667222

AFF1
AF4/FMR2 family member 1

1

5

Small-scale

0.437

High

667238

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.437

High

667256

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

6

Small-scale

0.437

High

667259

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

7

Small-scale

0.437

High

667335

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.437

High

667348

CE128
Centrosomal protein of 128 kDa

1

3

High-throughput

0.437

High

667433

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

1

High-throughput

0.437

High

667450

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

667463

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

7

Small-scale

0.437

High

667474

PDRG1
p53 and DNA damage-regulated protein 1

1

2

High-throughput

0.437

High

667479

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

Small-scale

0.437

High

344092

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

667243

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.426

High

667296

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

667437

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

667460

ELP3
Elongator complex protein 3

1

0

Small-scale

0.426

High

667514

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

3

Small-scale

0.408

High

667315

UT2
Urea transporter 2

1

1

High-throughput

0.407

High

667483

ASB6
Ankyrin repeat and SOCS box protein 6

4

0

High-throughput

0.364

High

667350

SYDE1
Rho GTPase-activating protein SYDE1

2

0

High-throughput

0.328

High

562996

MYH6
Myosin-6

1

0

Small-scale

0.292

High

249280

BRNP1
BMP/retinoic acid-inducible neural-specific protein 1

1

0

Small-scale

0.279

Low

667326

SAMTR
S-adenosylmethionine sensor upstream of mTORC1

1

0

High-throughput

0.279

Low

667330

FREM2
FRAS1-related extracellular matrix protein 2

1

0

High-throughput

0.279

Low

667375

GP156
Probable G-protein coupled receptor 156

1

0

High-throughput

0.279

Low

667384

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

667517

COLQ
Acetylcholinesterase collagenic tail peptide

1

0

High-throughput

0.279

Low

667362

PKHL1
Fibrocystin-L

1

0

High-throughput

0.269

Low

667372

FSIP1
Fibrous sheath-interacting protein 1

1

0

High-throughput

0.269

Low

667360

IFTAP
Intraflagellar transport-associated protein

1

0

Small-scale

0.265

Low

352977

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

420366

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.249

Low

516039

CSH2
Chorionic somatomammotropin hormone 2

1

0

Small-scale

0.249

Low

667328

PHLA2
Pleckstrin homology-like domain family A member 2

1

0

High-throughput

0.249

Low

667349

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

62450

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low

190309

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.232

Low

667486

USE1
Vesicle transport protein USE1

1

0

Small-scale

0.232

Low

667520

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025