HitPredict

Interactor 1: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	21653829, 37207277
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0046872 - metal ion binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 2221 Hs			1 415
+	Hs
		983063 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		ICA69_HUMAN (141-397): 3.18e-83: 264: 15.47
+	Hs
		1047167 CAC1C_HUMAN (1-2221): 0: 1887: 100.00		ICA1L_HUMAN (143-387): 1.08e-74: 242: 14.92