HitPredict

Interactor 1: ARHG7 (Q14155)
Rho guanine nucleotide exchange factor 7 (Beta-Pix) (COOL-1) (PAK-interacting exchange factor beta) (p85)
Gene: ARHGEF7

Interactor 2: SHAN3 (Q9BYB0)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2)
Gene: SHANK3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.843

The method score is based on:

Property Details
Experiments 12626503, 21653829
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_2~SH3_2
Common GO terms GO:0005829 - cytosol
GO:0043005 - neuron projection
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 803
Hs

1 1731
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024