Protein: STX12
Syntaxin-12

Gene: STX12
Organism: Homo sapiens
Interactions: 232
UniProt ID: Q86Y82

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0000407 - phagophore assembly site
GO:0005484 - SNAP receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1017694

STX4
Syntaxin-4

8

17

High-throughput

0.971

High

212911

STX6
Syntaxin-6

6

20

Small-scale

0.953

High

873559

SNAA
Alpha-soluble NSF attachment protein

6

20

Small-scale

0.948

High

1205352

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

5

20

Small-scale

0.936

High

178639

STX7
Syntaxin-7

5

17

High-throughput

0.927

High

261687

VAMP4
Vesicle-associated membrane protein 4

4

20

Small-scale

0.909

High

235191

STX10
Syntaxin-10

4

20

High-throughput

0.903

High

850580

VAMP7
Vesicle-associated membrane protein 7

4

20

High-throughput

0.903

High

1079365

VAMP3
Vesicle-associated membrane protein 3

4

20

High-throughput

0.903

High

1205360

SNAG
Gamma-soluble NSF attachment protein

4

20

High-throughput

0.903

High

1205363

VAMP8
Vesicle-associated membrane protein 8

4

20

High-throughput

0.903

High

1205392

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

4

20

High-throughput

0.903

High

1205399

STX8
Syntaxin-8

4

20

High-throughput

0.903

High

151600

GOSR2
Golgi SNAP receptor complex member 2

3

20

High-throughput

0.861

High

180894

YKT6
Synaptobrevin homolog YKT6

3

20

High-throughput

0.861

High

926226

VAMP2
Vesicle-associated membrane protein 2

3

20

High-throughput

0.861

High

1027510

STX5
Syntaxin-5

3

20

High-throughput

0.861

High

1205369

SNAB
Beta-soluble NSF attachment protein

3

20

High-throughput

0.861

High

309600

GOSR1
Golgi SNAP receptor complex member 1

3

9

High-throughput

0.847

High

1205350

SCFD2
Sec1 family domain-containing protein 2

3

0

High-throughput

0.816

High

306820

VAMP5
Vesicle-associated membrane protein 5

2

20

High-throughput

0.789

High

699276

STX2
Syntaxin-2

2

18

High-throughput

0.783

High

1083946

STX1A
Syntaxin-1A

2

18

High-throughput

0.783

High

320349

SNP29
Synaptosomal-associated protein 29

7

20

Small-scale

0.751

High

1205346

STXB6
Syntaxin-binding protein 6

2

4

High-throughput

0.726

High

118048

SNP23
Synaptosomal-associated protein 23

5

20

Small-scale

0.720

High

1200267

DTX2
Probable E3 ubiquitin-protein ligase DTX2

4

2

High-throughput

0.698

High

1130976

SNP47
Synaptosomal-associated protein 47

4

5

Small-scale

0.694

High

263279

SC22B
Vesicle-trafficking protein SEC22b

1

20

High-throughput

0.691

High

803944

NSF
Vesicle-fusing ATPase

3

13

High-throughput

0.675

High

58106

NBAS
NBAS subunit of NRZ tethering complex

3

2

High-throughput

0.667

High

58452

F234B
Protein FAM234B

3

1

High-throughput

0.667

High

940713

NOP14
Nucleolar protein 14

3

1

High-throughput

0.667

High

995009

GOGA2
Golgin subfamily A member 2

3

6

High-throughput

0.667

High

1021920

SEC20
Vesicle transport protein SEC20

3

7

High-throughput

0.667

High

1133591

STXB5
Syntaxin-binding protein 5

3

12

High-throughput

0.667

High

1205347

MSPD2
Motile sperm domain-containing protein 2

3

9

High-throughput

0.667

High

1205353

OPTN
Optineurin

3

4

High-throughput

0.667

High

1205361

GORS1
Golgi reassembly-stacking protein 1

3

3

High-throughput

0.667

High

1205364

NOC4L
Nucleolar complex protein 4 homolog

3

1

High-throughput

0.667

High

1205375

TBC17
TBC1 domain family member 17

3

6

High-throughput

0.667

High

1205385

USE1
Vesicle transport protein USE1

3

7

High-throughput

0.667

High

1205390

STX18
Syntaxin-18

3

7

High-throughput

0.667

High

1205393

TBK1
Serine/threonine-protein kinase TBK1

3

6

High-throughput

0.667

High

507105

LAMP1
Lysosome-associated membrane glycoprotein 1

3

6

High-throughput

0.656

High

350312

RASK
GTPase KRas

3

20

High-throughput

0.640

High

1205391

ZN219
Zinc finger protein 219

3

0

High-throughput

0.638

High

1023426

TRDN
Triadin

2

6

High-throughput

0.628

High

364340

TFR1
Transferrin receptor protein 1

2

3

High-throughput

0.621

High

1205380

VPS45
Vacuolar protein sorting-associated protein 45

1

20

High-throughput

0.618

High

207561

RNF13
E3 ubiquitin-protein ligase RNF13

2

4

High-throughput

0.611

High

844600

RAB5C
Ras-related protein Rab-5C

2

13

High-throughput

0.611

High

1205345

RN149
E3 ubiquitin-protein ligase RNF149

2

6

High-throughput

0.611

High

563719

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

3

3

High-throughput

0.609

High

834429

EI2BB
Translation initiation factor eIF2B subunit beta

3

2

High-throughput

0.609

High

1025650

EI2BE
Translation initiation factor eIF2B subunit epsilon

3

2

High-throughput

0.609

High

1051820

EI2BA
Translation initiation factor eIF2B subunit alpha

3

2

High-throughput

0.609

High

1191879

FRMD5
FERM domain-containing protein 5

3

7

High-throughput

0.609

High

1205349

TBC15
TBC1 domain family member 15

3

6

High-throughput

0.609

High

1205362

ADPGK
ADP-dependent glucokinase

3

1

High-throughput

0.609

High

1205368

F234A
Protein FAM234A

3

1

High-throughput

0.609

High

1205379

EI2BG
Translation initiation factor eIF2B subunit gamma

3

1

High-throughput

0.609

High

1205395

OPN4
Melanopsin

3

1

High-throughput

0.609

High

1205396

EI2BD
Translation initiation factor eIF2B subunit delta

3

2

High-throughput

0.609

High

1205407

5MP1
eIF5-mimic protein 1

3

1

High-throughput

0.609

High

516072

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

3

High-throughput

0.606

High

1190947

RIC3
Protein RIC-3

2

1

High-throughput

0.606

High

1205340

EMC5
ER membrane protein complex subunit 5

2

3

High-throughput

0.606

High

1205381

KISHB
Protein kish-B

2

1

High-throughput

0.606

High

1205401

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

2

High-throughput

0.606

High

1205402

STB5L
Syntaxin-binding protein 5-like

2

12

High-throughput

0.606

High

348760

RASN
GTPase NRas

2

20

High-throughput

0.584

High

591915

RAB4A
Ras-related protein Rab-4A

2

16

High-throughput

0.584

High

845584

RAB9A
Ras-related protein Rab-9A

2

16

High-throughput

0.584

High

914188

RB11A
Ras-related protein Rab-11A

2

10

High-throughput

0.584

High

965740

IFM3
Interferon-induced transmembrane protein 3

2

4

High-throughput

0.584

High

1205398

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

2

1

Small-scale

0.581

High

1134975

GORAB
RAB6-interacting golgin

2

0

High-throughput

0.580

High

1205378

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.580

High

87582

C9JXZ5
Vesicle-associated membrane protein 8

1

20

High-throughput

0.575

High

92395

E9PCW1
Golgi SNAP receptor complex member 1

1

9

High-throughput

0.575

High

676569

CTR1
High affinity cationic amino acid transporter 1

2

9

High-throughput

0.574

High

893283

SNP25
Synaptosomal-associated protein 25

2

20

Small-scale

0.571

High

503227

PPAL
Lysosomal acid phosphatase

2

1

High-throughput

0.558

High

770627

TXLNA
Alpha-taxilin

2

7

High-throughput

0.558

High

296245

AQP8
Aquaporin-8

2

13

High-throughput

0.553

High

307708

LERL1
Leptin receptor overlapping transcript-like 1

2

2

High-throughput

0.553

High

1037626

AQP6
Aquaporin-6

2

17

High-throughput

0.553

High

1068282

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

4

High-throughput

0.553

High

1108579

SOAT
Sodium-dependent organic anion transporter

2

6

High-throughput

0.553

High

1205341

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

2

High-throughput

0.553

High

1205342

TM86B
Lysoplasmalogenase TMEM86B

2

2

High-throughput

0.553

High

1205343

KASH5
Protein KASH5

2

6

High-throughput

0.553

High

1205355

PLPR2
Phospholipid phosphatase-related protein type 2

2

4

High-throughput

0.553

High

1205366

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

2

High-throughput

0.553

High

1205382

TM14B
Transmembrane protein 14B

2

2

High-throughput

0.553

High

1205405

TMX2
Thioredoxin-related transmembrane protein 2

2

4

High-throughput

0.553

High

168419

SCAM1
Secretory carrier-associated membrane protein 1

1

9

High-throughput

0.536

High

168557

SCAM2
Secretory carrier-associated membrane protein 2

1

9

High-throughput

0.536

High

254352

ATP9A
Probable phospholipid-transporting ATPase IIA

1

4

High-throughput

0.536

High

275050

RENR
Renin receptor

1

1

High-throughput

0.536

High

497261

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.536

High

514862

MPRI
Cation-independent mannose-6-phosphate receptor

1

3

High-throughput

0.536

High

750864

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.536

High

864922

PTTG
Pituitary tumor-transforming gene 1 protein-interacting protein

1

1

High-throughput

0.536

High

895155

RAB2A
Ras-related protein Rab-2A

1

14

High-throughput

0.536

High

896646

RAB14
Ras-related protein Rab-14

1

15

High-throughput

0.536

High

918901

RAB1A
Ras-related protein Rab-1A

1

11

High-throughput

0.536

High

972544

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

4

High-throughput

0.536

High

1034919

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

4

High-throughput

0.536

High

1079938

RB11B
Ras-related protein Rab-11B

1

12

High-throughput

0.536

High

1205344

AT11C
Phospholipid-transporting ATPase IG

1

4

High-throughput

0.536

High

1205356

ZDH12
Palmitoyltransferase ZDHHC12

1

7

High-throughput

0.536

High

1205406

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

2

High-throughput

0.536

High

1205408

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

451488

CLCA
Clathrin light chain A

1

0

High-throughput

0.513

High

620524

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

0

High-throughput

0.513

High

648042

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.513

High

1069407

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

1205337

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1205374

RPAP3
RNA polymerase II-associated protein 3

1

0

High-throughput

0.513

High

1205384

LMBD1
Lysosomal cobalamin transport escort protein LMBD1

1

0

High-throughput

0.513

High

1205404

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.513

High

1067443

EEA1
Early endosome antigen 1

1

2

Small-scale

0.501

High

1205371

DNJC5
DnaJ homolog subfamily C member 5

1

5

High-throughput

0.501

High

1205357

VPS50
Syndetin

1

3

Small-scale

0.500

High

315258

ABCA1
Phospholipid-transporting ATPase ABCA1

1

0

Small-scale

0.493

High

155916

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

2

High-throughput

0.489

High

282233

SEGN
Secretagogin

1

6

High-throughput

0.489

High

816602

CXA8
Gap junction alpha-8 protein

1

7

High-throughput

0.489

High

986093

KDSR
3-ketodihydrosphingosine reductase

1

2

High-throughput

0.489

High

1016617

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

2

High-throughput

0.489

High

1205338

NRSN1
Neurensin-1

1

2

High-throughput

0.489

High

1205370

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

15

High-throughput

0.489

High

1205377

LRRC4
Leucine-rich repeat-containing protein 4

1

4

High-throughput

0.489

High

1205383

T106B
Transmembrane protein 106B

1

1

High-throughput

0.489

High

1205409

ENPP4
Bis(5'-adenosyl)-triphosphatase ENPP4

1

1

High-throughput

0.489

High

360116

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

8

High-throughput

0.481

High

160079

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

19

Small-scale

0.479

High

167963

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

169516

BET1
BET1 homolog

1

20

High-throughput

0.479

High

205620

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

349447

RASH
GTPase HRas

1

19

High-throughput

0.479

High

504349

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

527587

LAMP2
Lysosome-associated membrane glycoprotein 2

1

6

High-throughput

0.479

High

553108

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

564597

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

567148

CXA1
Gap junction alpha-1 protein

1

7

High-throughput

0.479

High

591613

RAB3B
Ras-related protein Rab-3B

1

9

High-throughput

0.479

High

592356

RAB5A
Ras-related protein Rab-5A

1

14

High-throughput

0.479

High

648815

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.479

High

651611

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

720850

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

845054

RAB7A
Ras-related protein Rab-7a

1

13

High-throughput

0.479

High

884530

RAB25
Ras-related protein Rab-25

1

13

High-throughput

0.479

High

892468

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

894185

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

900656

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

912979

ARF6
ADP-ribosylation factor 6

1

5

High-throughput

0.479

High

915802

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

941125

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

974902

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

1035868

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1063924

TNIP1
TNFAIP3-interacting protein 1

1

6

High-throughput

0.479

High

1070280

RAB35
Ras-related protein Rab-35

1

9

High-throughput

0.479

High

1146583

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

1151943

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1183449

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1188275

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

1205351

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1205376

NMRL1
NmrA-like family domain-containing protein 1

1

1

High-throughput

0.479

High

1205388

ANFY1
Rabankyrin-5

1

3

High-throughput

0.479

High

1205389

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

1205394

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

1205400

LAMP3
Lysosome-associated membrane glycoprotein 3

1

6

High-throughput

0.479

High

807769

MAP1B
Microtubule-associated protein 1B

1

1

High-throughput

0.470

High

1205387

MYEF2
Myelin expression factor 2

1

1

High-throughput

0.470

High

967262

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1041963

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1083670

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.458

High

1205367

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

730

A0A087WXB0
Secretory carrier-associated membrane protein

1

9

High-throughput

0.445

High

789304

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.445

High

1060681

NTCP
Hepatic sodium/bile acid cotransporter

1

6

High-throughput

0.439

High

1128638

F209A
Protein FAM209A

1

2

High-throughput

0.439

High

154385

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

3

High-throughput

0.437

High

508087

FGFR1
Fibroblast growth factor receptor 1

1

3

Small-scale

0.437

High

525980

IFM1
Interferon-induced transmembrane protein 1

1

4

High-throughput

0.437

High

545479

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.437

High

547340

VATB1
V-type proton ATPase subunit B, kidney isoform

1

2

High-throughput

0.437

High

594756

ATP4A
Potassium-transporting ATPase alpha chain 1

1

4

Small-scale

0.437

High

670098

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.437

High

1021807

TP4A2
Protein tyrosine phosphatase type IVA 2

1

5

Small-scale

0.437

High

1045337

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

2

High-throughput

0.437

High

1076646

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.437

High

1088130

DDR2
Discoidin domain-containing receptor 2

1

9

High-throughput

0.437

High

1119552

MIDN
Midnolin

1

2

High-throughput

0.437

High

1165731

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1170668

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1203754

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1205372

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.437

High

1205373

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.437

High

1205386

TM216
Transmembrane protein 216

1

2

High-throughput

0.437

High

378093

PRIO
Major prion protein

1

0

High-throughput

0.426

High

240078

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.407

High

318292

VATG2
V-type proton ATPase subunit G 2

1

2

High-throughput

0.407

High

1047146

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.407

High

1205358

CC138
Coiled-coil domain-containing protein 138

3

0

High-throughput

0.347

High

147100

NEMP1
Nuclear envelope integral membrane protein 1

2

0

High-throughput

0.316

High

1024628

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

1170376

MFSD6
Major facilitator superfamily domain-containing protein 6

2

0

High-throughput

0.316

High

1205339

S66A2
Solute carrier family 66 member 2

2

0

High-throughput

0.316

High

1205359

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.316

High

1205365

B2L13
Bcl-2-like protein 13

2

0

High-throughput

0.316

High

206389

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.279

Low

314351

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

High-throughput

0.279

Low

621554

IL32
Interleukin-32

1

0

High-throughput

0.279

Low

686698

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

724908

MYH9
Myosin-9

1

0

High-throughput

0.279

Low

899975

VA0D1
V-type proton ATPase subunit d 1

1

0

High-throughput

0.279

Low

1205354

KBP
KIF-binding protein

1

0

High-throughput

0.279

Low

1205397

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.279

Low

1205403

LTOR2
Ragulator complex protein LAMTOR2

1

0

High-throughput

0.279

Low

672975

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.251

Low

1128807

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low

100920

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

119438

LEG9
Galectin-9

1

0

High-throughput

0.249

Low

532876

TF
Tissue factor

1

0

High-throughput

0.249

Low

779693

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

897180

TM258
Transmembrane protein 258

1

0

High-throughput

0.249

Low

1159145

ANM9
Protein arginine N-methyltransferase 9

1

0

High-throughput

0.249

Low

1205348

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024