HitPredict

Interactor 1: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Interactor 2: KCJ12 (Q14500)
ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12)
Gene: KCNJ12

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	24550280, 30126976
Identification Methods	phage display, p8 filamentous phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1630 Hs			1 433
+	Hs
		929767 SCRIB_HUMAN (1-1630): 0: 978: 100.00		KCNJ2_HUMAN (6-433): 0: 686: 70.70
+	Hs
		816149 SCRIB_HUMAN (1-1630): 0: 978: 100.00		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Hs
		942342 DLG4_HUMAN (812-1187): 3.22e-49: 190: 22.42		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Rn
		677769 DLG4_RAT (812-1187): 3.08e-49: 190: 22.42		KCJ12_RAT (1-433): 0: 726: 95.84
+	Hs
		929762 DLG4_HUMAN (812-1187): 3.22e-49: 190: 22.42		KCNJ2_HUMAN (6-433): 0: 686: 70.70
+	Hs
		1054723 DLG2_HUMAN (587-879): 1.21e-20: 101: 18.67		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Hs
		1054724 DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23		KCJ12_HUMAN (1-433): 0: 762: 100.00
+	Hs
		80982 DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68		KCJ18_HUMAN (1-433): 0: 757: 98.61
+	Rn
		852400 DLG2_RAT (587-879): 2.66e-21: 103: 18.52		KCJ12_RAT (1-433): 0: 726: 95.84
+	Rn
		852399 DLG3_RAT (724-947): 3.57e-19: 96.3: 31.23		KCJ12_RAT (1-433): 0: 726: 95.84
+	Mm
		852403 DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42		KCNJ4_MOUSE (32-433): 0: 616: 63.64
+	Hs
		816146 DLG4_HUMAN (812-1187): 3.22e-49: 190: 22.42		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Mm
		1143540 DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42		Q9QYK8_MOUSE (39-427): 0: 600: 63.85
+	Rn
		1144360 DLG2_RAT (587-879): 2.66e-21: 103: 18.52		KCNJ2_RAT (6-433): 0: 682: 70.93
+	Hs
		816189 LRRC1_HUMAN (1-277): 7.16e-72: 252: 31.77		KCNJ6_HUMAN (40-381): 0: 527: 52.92
+	Hs
		816150 DLG2_HUMAN (587-879): 1.21e-20: 101: 18.67		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Hs
		816147 DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68		KCNJ4_HUMAN (31-433): 0: 602: 63.58
+	Mm
		291382 DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42		KCNJ1_MOUSE (39-358): 1.54e-172: 489: 49.85
+	Mm
		1143568 DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42		KCJ16_MOUSE (36-363): 2.83e-163: 467: 49.39
+	Mm
		1143532 DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42		KCJ10_MOUSE (42-354): 1.53e-159: 456: 44.76