Interactor 1: IKKE (Q14164)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)
Gene: IKBKE
Interactor 2: TANK (Q92844)
TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF)
Gene: TANK
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.60 | 0.754 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25852190, 10759890, 33961781, 17823124, 21212807, 23007157, 17568778, 21931555 |
| Identification Methods | affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, cross-linking study, luminescence based mammalian interactome mapping |
| Interaction Type | physical association, direct interaction, association, covalent binding |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0032481 - positive regulation of type I interferon production GO:0051607 - defense response to virus and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
