HitPredict

Interactor 1: IKKE (Q14164)
Inhibitor of nuclear factor kappa-B kinase subunit epsilon (I-kappa-B kinase epsilon) (IKK-E) (IKK-epsilon) (IkBKE) (EC 2.7.11.10) (Inducible I kappa-B kinase) (IKK-i)
Gene: IKBKE

Interactor 2: Q96BE0 (Q96BE0)
Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)
Gene: Q96BE0

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 716 Hs			1 269
+	Hs
		504064 IKKE_HUMAN (1-716): 1.32e-170: 508: 100.00		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		1050214 IKKE_HUMAN (1-716): 1.32e-170: 508: 100.00		Q53FC7_HUMAN (1-269): 5.5e-126: 373: 68.77
+	Hs
		504911 TBK1_HUMAN (1-714): 4.2e-162: 486: 48.13		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		158411 IKKB_HUMAN (9-701): 6.33e-128: 399: 18.97		HS71L_HUMAN (1-269): 2.79e-134: 395: 76.58
+	Hs
		158382 IKKB_HUMAN (9-701): 6.33e-128: 399: 18.97		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		254440 ROCK2_HUMAN (7-705): 1.81e-120: 393: 16.15		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		1123964 Q59GL9_HUMAN (61-520): 3.28e-112: 349: 22.57		Q96BE0_HUMAN (1-269): 3.21e-125: 358: 100.00
+	Hs
		503719 KS6A3_HUMAN (6-294): 2.42e-88: 294: 22.34		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		504119 KS6A1_HUMAN (4-348): 2.36e-88: 294: 20.17		HSP7C_HUMAN (1-269): 1.08e-130: 385: 100.00
+	Hs
		564041 KS6A3_HUMAN (6-294): 2.42e-88: 294: 22.34		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15
+	Hs
		564080 KS6A1_HUMAN (4-348): 2.36e-88: 294: 20.17		HSP76_HUMAN (1-269): 5.75e-126: 373: 69.15
+	Dm
		669799 IKKB_DROME (1-317): 5.09e-29: 125: 31.77		HSP7A_DROME (1-269): 1.62e-131: 387: 69.89
+	Dm
		505090 IKKB_DROME (1-317): 5.09e-29: 125: 31.77		HSP7D_DROME (1-235): 1.12e-128: 380: 82.55