Interactor 1: DOCK1 (Q14185)
Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)
Gene: DOCK1

Interactor 2: ELMO1 (Q92556)
Engulfment and cell motility protein 1 (Protein ced-12 homolog)
Gene: ELMO1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 20016009, 15700267, 26186194, 21930703, 26882976, 28514442, 11595183, 12134158, 33961781, 16495483, 20732417, 30853625, 15247908, 18768751, 15723800
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DOCK_N~PH_12
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006911 - phagocytosis, engulfment
GO:0006915 - apoptotic process
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024