HitPredict

Interactor 1: TFDP2 (Q14188)
Transcription factor Dp-2 (E2F dimerization partner 2)
Gene: TFDP2

Interactor 2: E2F2 (Q14209)
Transcription factor E2F2 (E2F-2)
Gene: E2F2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.895

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 7739537
Identification Methods affinity chromatography technology, comigration in non denaturing gel electrophoresis, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DP~E2F_CC-MB, E2F_TDP~E2F_TDP
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0007049 - cell cycle
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 446
Hs

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Last updated: 15 Jul 2024