HitPredict

Interactor 1: DPYL1 (Q14194)
Dihydropyrimidinase-related protein 1 (DRP-1) (Collapsin response mediator protein 1) (CRMP-1) (Inactive dihydropyrimidinase) (Unc-33-like phosphoprotein 3) (ULIP-3)
Gene: CRMP1

Interactor 2: DPYL3 (Q14195)
Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1)
Gene: DPYSL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.936

The method score is based on:

Property Details
Experiments 25416956, 32296183, 28514442, 33961781, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Amidohydro_1~Amidohydro_1
Common GO terms GO:0005829 - cytosol
GO:0010977 - negative regulation of neuron projection development
GO:0016812 - hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GO:0030426 - growth cone
GO:0031005 - filamin binding
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 572
Hs

1 570
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Last updated: 15 Jul 2024