HitPredict

Interactor 1: ZBT16 (Q05516)
Zinc finger and BTB domain-containing protein 16 (Promyelocytic leukemia zinc finger protein) (Zinc finger protein 145) (Zinc finger protein PLZF)
Gene: ZBTB16

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22632832
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 673 Hs			1 768
+	Hs
		1114106 ZN184_HUMAN (145-673): 0: 551: 22.99		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114522 ZN624_HUMAN (91-673): 0: 547: 19.50		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113421 Z585A_HUMAN (132-673): 1.69e-178: 528: 20.97		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113108 ZN268_HUMAN (93-673): 1.44e-175: 526: 21.01		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1051149 ZNF91_HUMAN (141-673): 1.55e-169: 518: 21.67		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113833 ZN480_HUMAN (148-673): 9.1e-178: 518: 23.12		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113712 ZN565_HUMAN (371-654): 1.5e-135: 410: 35.44		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113663 ZN567_HUMAN (291-627): 5.33e-133: 407: 29.50		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113405 ZN544_HUMAN (144-673): 1.71e-127: 395: 20.60		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		601936 ZNF7_HUMAN (267-598): 2.81e-108: 344: 26.48		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114043 ZN583_HUMAN (323-673): 1.96e-109: 343: 24.22		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113647 ZN100_HUMAN (432-673): 1.33e-105: 333: 34.71		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113713 ZN383_HUMAN (355-599): 8.52e-107: 333: 35.77		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		76405 ZN879_HUMAN (87-426): 2.17e-75: 254: 9.86		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114477 ZN226_HUMAN (87-418): 1.59e-58: 213: 9.78		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114555 ZN629_HUMAN (110-598): 7.01e-56: 206: 13.31		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		599939 ZNF12_HUMAN (110-458): 8.52e-54: 198: 13.39		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113710 ZN557_HUMAN (385-625): 7.58e-50: 181: 38.17		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113304 ZN569_HUMAN (87-373): 8.37e-45: 172: 9.62		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Mm
		1190768 Q3UQ17_MOUSE (120-460): 2.57e-37: 150: 11.30		CUL3_MOUSE (1-768): 0: 941: 99.48