HitPredict

Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: ARP10 (Q9NZ32)
Actin-related protein 10 (Actin-related protein 11) (hARP11)
Gene: ACTR10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	27173435, 26638075, 28514442, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1278 Hs			1 417
+	Hs
		891760 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		ACTB_HUMAN (10-384): 1.71e-173: 491: 23.94
+	Hs
		929862 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		ACTG_HUMAN (10-384): 2.53e-173: 491: 24.44
+	Hs
		932151 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		ACTC_HUMAN (7-384): 4e-172: 487: 24.51
+	Hs
		915383 DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00		ACTA_HUMAN (7-384): 4.62e-171: 485: 24.26
+	Hs
		675241 CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32		ARP10_HUMAN (1-417): 0: 565: 100.00
+	Dm
		528064 DCTN1_DROME (23-1233): 4.05e-103: 358: 31.82		Q9VWE8_DROME (1-394): 1.1e-92: 285: 40.25
+	Rn
		892236 MYH10_RAT (664-1275): 1.11e-22: 107: 10.46		ACTB_RAT (10-384): 1.71e-173: 491: 23.94
+	Hs
		725136 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		ACTC_HUMAN (7-384): 4e-172: 487: 24.51
+	Hs
		725135 MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13		ACTH_HUMAN (8-384): 2.65e-170: 483: 24.57
+	Hs
		724738 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		ACTB_HUMAN (10-384): 1.71e-173: 491: 23.94
+	Hs
		724762 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		ACTG_HUMAN (10-384): 2.53e-173: 491: 24.44
+	Mm
		892205 MYH9_MOUSE (826-1275): 8.37e-15: 82.2: 10.13		ACTB_MOUSE (10-384): 1.71e-173: 491: 23.94
+	Rn
		892228 MYH9_RAT (805-1277): 3.43e-14: 80.2: 12.76		ACTB_RAT (10-384): 1.71e-173: 491: 23.94
+	Hs
		724766 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		ACTC_HUMAN (7-384): 4e-172: 487: 24.51
+	Hs
		724767 MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54		ACTS_HUMAN (7-384): 5.55e-172: 487: 24.26