Interactor 1: EI2BA (Q14232)
Translation initiation factor eIF2B subunit alpha (eIF2B GDP-GTP exchange factor subunit alpha)
Gene: EIF2B1

Interactor 2: EI2BA (Q14232)
Translation initiation factor eIF2B subunit alpha (eIF2B GDP-GTP exchange factor subunit alpha)
Gene: EIF2B1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 25416956, 32296183, 25502805, 31515488, unassigned1304
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~IF-2B
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 9 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 305
Hs

1 305
+ Hs
+ Hs
+ Dm
+ Sc
+ Hs
+ Hs
+ Ce
+ Dm
+ Sc
+ Sc
+ Sp
+ Hs
+ Hv

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024