HitPredict

Interactor 1: IF4A2 (Q14240)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 2527
+	Hs
		1123930 Q59F66_HUMAN (25-407): 5.91e-131: 395: 31.20		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		111380 J3KTA4_HUMAN (10-407): 4.54e-132: 394: 30.30		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		571483 DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		66564 A8K7F6_HUMAN (3-407): 2.95e-134: 392: 89.63		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		134075 DDX3X_HUMAN (2-406): 3.77e-128: 385: 29.51		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		2821 A0A0D9SF53_HUMAN (2-406): 2.64e-127: 385: 29.51		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		757645 IF4A3_HUMAN (3-407): 2.28e-130: 382: 67.65		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		110651 H3BQK0_HUMAN (19-407): 6.84e-88: 276: 39.95		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		201203 DDX5_HUMAN (10-407): 3.86e-132: 394: 30.30		M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83