Protein: SEC31
Protein transport protein SEC31 (Protein WEB1)

Gene: SEC31
Organism: Saccharomyces cerevisiae S288C
Interactions: 110
UniProt ID: P38968

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0007029 - endoplasmic reticulum organization
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

808391

SEC13
Protein transport protein SEC13

20

19

Small-scale

0.989

High

808375

SEC24
Protein transport protein SEC24

6

6

Small-scale

0.950

High

582462

SEC23
Protein transport protein SEC23

5

6

Small-scale

0.927

High

808380

SEC16
COPII coat assembly protein SEC16

3

0

Small-scale

0.835

High

666458

DBP2
ATP-dependent RNA helicase DBP2

2

7

High-throughput

0.717

High

633547

SAR1
Small COPII coat GTPase SAR1

1

8

Small-scale

0.647

High

808392

CORO
Coronin-like protein

1

16

High-throughput

0.618

High

383126

RLA4
Large ribosomal subunit protein P2B

2

2

High-throughput

0.567

High

808393

CLP1
mRNA cleavage and polyadenylation factor CLP1

2

2

High-throughput

0.567

High

745334

EMP24
Endosomal protein P24B

1

3

Small-scale

0.561

High

808387

TMEDA
Endoplasmic reticulum vesicle protein 25

1

4

Small-scale

0.561

High

410131

RL25
Large ribosomal subunit protein uL23

2

1

High-throughput

0.558

High

779227

CENPA
Histone H3-like centromeric protein CSE4

1

20

High-throughput

0.553

High

808370

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.553

High

808372

DHH1
ATP-dependent RNA helicase DHH1

1

13

High-throughput

0.553

High

808381

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.553

High

808396

DBP10
ATP-dependent RNA helicase DBP10

1

14

High-throughput

0.553

High

585936

CSK21
Casein kinase II subunit alpha

2

15

High-throughput

0.537

High

622952

CSK22
Casein kinase II subunit alpha'

2

17

High-throughput

0.537

High

808379

CSK2B
Casein kinase II subunit beta

2

2

High-throughput

0.537

High

597136

BIP
Endoplasmic reticulum chaperone BiP

1

16

High-throughput

0.536

High

149763

RS9A
Small ribosomal subunit protein uS4A

2

5

High-throughput

0.521

High

503044

RS22A
Small ribosomal subunit protein uS8A

2

1

High-throughput

0.521

High

579381

HSC82
ATP-dependent molecular chaperone HSC82

2

12

High-throughput

0.521

High

727023

HS104
Heat shock protein 104

2

3

High-throughput

0.521

High

763885

SPT10
Protein SPT10

1

0

High-throughput

0.517

High

569786

RL30
Large ribosomal subunit protein eL30

1

2

High-throughput

0.514

High

808368

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.514

High

808369

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.514

High

523941

HSP71
Heat shock protein SSA1

2

12

High-throughput

0.504

High

526690

HSP72
Heat shock protein SSA2

2

12

High-throughput

0.504

High

544863

SSB1
Ribosome-associated molecular chaperone SSB1

2

11

High-throughput

0.504

High

652924

BET1
Protein transport protein BET1

1

2

Small-scale

0.501

High

633465

PP11
Serine/threonine-protein phosphatase PP1-1

1

12

Small-scale

0.489

High

154167

RL36B
Large ribosomal subunit protein eL36B

1

2

High-throughput

0.489

High

432580

RL7A
Large ribosomal subunit protein uL30A

1

4

High-throughput

0.489

High

802078

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

4

High-throughput

0.489

High

808377

RL33B
Large ribosomal subunit protein eL33B

1

2

High-throughput

0.489

High

808378

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.489

High

808388

RL6A
Large ribosomal subunit protein eL6A

1

2

High-throughput

0.489

High

808397

RL13A
Large ribosomal subunit protein eL13A

1

2

High-throughput

0.489

High

570250

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.481

High

679673

CDC48
Cell division control protein 48

1

6

High-throughput

0.479

High

803538

RPN1
26S proteasome regulatory subunit RPN1

1

5

High-throughput

0.479

High

670700

SIS1
Protein SIS1

1

8

High-throughput

0.470

High

796925

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

808373

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

808389

SHR3
Secretory component protein SHR3

1

0

Small-scale

0.458

High

808395

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

808398

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.458

High

709380

HRR25
Casein kinase I homolog HRR25

1

10

Small-scale

0.457

High

808385

PEF1
Peflin

1

4

Small-scale

0.457

High

760585

TSA1
Peroxiredoxin TSA1

1

7

High-throughput

0.457

High

675996

MAS5
Mitochondrial protein import protein MAS5

1

9

High-throughput

0.445

High

392725

HSP82
ATP-dependent molecular chaperone HSP82

1

12

High-throughput

0.437

High

416237

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

9

High-throughput

0.437

High

433641

RL26A
Large ribosomal subunit protein uL24A

1

5

High-throughput

0.437

High

435092

RS3
Small ribosomal subunit protein uS3

1

5

High-throughput

0.437

High

441907

RS14A
Small ribosomal subunit protein uS11A

1

6

High-throughput

0.437

High

455064

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

504213

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

510485

HSP77
Import motor subunit, mitochondrial

1

18

High-throughput

0.437

High

511421

RL43B
Large ribosomal subunit protein eL43B

1

3

High-throughput

0.437

High

512439

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

513998

RL18B
Large ribosomal subunit protein eL18B

1

4

High-throughput

0.437

High

514640

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

581861

SYKC
Lysine--tRNA ligase, cytoplasmic

1

9

High-throughput

0.437

High

594366

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

647108

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

4

High-throughput

0.437

High

674624

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.437

High

687590

SYLC
Leucine--tRNA ligase, cytoplasmic

1

10

High-throughput

0.437

High

747360

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

778329

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

785923

LONM
Lon protease homolog, mitochondrial

1

13

High-throughput

0.437

High

794983

NU170
Nucleoporin NUP170

1

3

High-throughput

0.437

High

795340

ATG8
Autophagy-related protein 8

1

5

High-throughput

0.437

High

802545

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

9

High-throughput

0.437

High

802618

YHI0
Putative proline--tRNA ligase YHR020W

1

3

High-throughput

0.437

High

803116

ECM29
Proteasome component ECM29

1

8

High-throughput

0.437

High

806704

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.437

High

808376

RLP7
Ribosome biogenesis protein RLP7

1

4

High-throughput

0.437

High

808386

SAM50
Sorting assembly machinery 50 kDa subunit

1

2

High-throughput

0.437

High

808390

TOM1
E3 ubiquitin-protein ligase TOM1

1

5

High-throughput

0.437

High

808394

AP3D
AP-3 complex subunit delta

1

4

High-throughput

0.437

High

394555

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.407

High

427278

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.407

High

435965

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.407

High

453598

PYR1
Multifunctional protein URA2

1

6

High-throughput

0.407

High

511336

RL43A
Large ribosomal subunit protein eL43A

1

3

High-throughput

0.407

High

531739

RL4A
Large ribosomal subunit protein uL4A

1

3

High-throughput

0.407

High

570015

RL3
Large ribosomal subunit protein uL3

1

6

High-throughput

0.407

High

592245

VATB
V-type proton ATPase subunit B

1

6

High-throughput

0.407

High

684724

RL5
Large ribosomal subunit protein uL18

1

4

High-throughput

0.407

High

689456

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.407

High

741576

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.407

High

752255

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

803391

RL14B
Large ribosomal subunit protein eL14B

1

4

High-throughput

0.407

High

808371

RS14B
Small ribosomal subunit protein uS11B

1

6

High-throughput

0.407

High

808374

HSP7E
Heat shock protein SSC3, mitochondrial

1

18

High-throughput

0.407

High

808383

RL4B
Large ribosomal subunit protein uL4B

1

3

High-throughput

0.407

High

808384

NUP84
Nucleoporin NUP84

1

2

Small-scale

0.407

High

640711

RT28
Small ribosomal subunit protein uS15m

2

0

High-throughput

0.324

High

808367

STM1
Suppressor protein STM1

2

0

High-throughput

0.318

High

511796

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.279

Low

558717

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

707088

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

753369

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

764071

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

802174

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

808382

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025