HitPredict

Interactor 1: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Interactor 2: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030036 - actin cytoskeleton organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 550 Hs			1 1117
+	Hs
		1052219 SRC8_HUMAN (1-550): 0: 559: 100.00		CYTSB_HUMAN (167-1117): 3.95e-60: 226: 38.76
+	Hs
		211580 SRC8_HUMAN (1-550): 0: 559: 100.00		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		724825 SRC8_HUMAN (1-550): 0: 559: 100.00		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		1052356 SRC8_HUMAN (1-550): 0: 559: 100.00		MYH15_HUMAN (313-1073): 6.77e-23: 108: 10.74
+	Rn
		555261 SPTN1_RAT (213-549): 1.1e-33: 138: 14.12		ACTN1_RAT (1009-1116): 1.18e-49: 192: 42.20
+	Hs
		724801 MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		1078836 ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99		CYTSB_HUMAN (167-1117): 3.95e-60: 226: 38.76
+	Hs
		1232344 PACN2_HUMAN (176-550): 4.93e-40: 153: 15.37		MILK1_HUMAN (1011-1115): 2.96e-36: 150: 41.51
+	Hs
		581026 PLCG1_HUMAN (212-549): 1.13e-35: 144: 16.48		MILK1_HUMAN (1011-1115): 2.96e-36: 150: 41.51
+	Hs
		724817 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		1232328 PACN1_HUMAN (241-549): 2.37e-31: 128: 16.86		MILK1_HUMAN (1011-1115): 2.96e-36: 150: 41.51
+	Hs
		1232326 SH3G1_HUMAN (365-549): 6.52e-31: 125: 17.01		MILK1_HUMAN (1011-1115): 2.96e-36: 150: 41.51
+	Hs
		298946 SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Mm
		1113251 SRBS2_MOUSE (452-549): 1.51e-11: 69.6: 22.00		ACTN1_MOUSE (1009-1116): 1e-49: 193: 42.20
+	Hs
		207844 PPIP1_HUMAN (198-549): 4.97e-33: 132: 15.18		MYH13_HUMAN (278-1070): 1.15e-29: 130: 10.89
+	Hs
		211443 SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Hs
		522612 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		MYH7_HUMAN (2-615): 3.07e-22: 106: 8.32
+	Hs
		506818 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		SPTB1_HUMAN (1012-1115): 7.3e-16: 85.5: 47.62
+	Hs
		298957 SRBS2_HUMAN (447-549): 1.56e-11: 69.2: 21.91		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		67893 SH3G1_HUMAN (365-549): 6.52e-31: 125: 17.01		SMTL1_HUMAN (1011-1113): 3.78e-15: 81.6: 43.27