Protein: RPB1
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)

Gene: RPB1, POLR2A
Organism: Homo sapiens
Interactions: 444
UniProt ID: P24928

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001055 - RNA polymerase II activity
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

123855

SPT5H
Transcription elongation factor SPT5

11

4

Small-scale

0.978

High

624849

RPB7
DNA-directed RNA polymerase II subunit RPB7

10

12

Small-scale

0.976

High

583647

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

7

14

Small-scale

0.968

High

181390

RPB4
DNA-directed RNA polymerase II subunit RPB4

7

8

Small-scale

0.967

High

612955

TCEA1
Transcription elongation factor A protein 1

8

8

Small-scale

0.965

High

624792

T2FA
General transcription factor IIF subunit 1

7

1

Small-scale

0.963

High

583394

RPB3
DNA-directed RNA polymerase II subunit RPB3

7

18

Small-scale

0.962

High

624822

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

7

10

Small-scale

0.960

High

624840

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

6

10

Small-scale

0.950

High

624823

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

6

11

Small-scale

0.944

High

624783

RPB2
DNA-directed RNA polymerase II subunit RPB2

5

20

Small-scale

0.918

High

624954

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

4

3

Small-scale

0.899

High

624795

RPB9
DNA-directed RNA polymerase II subunit RPB9

4

20

Small-scale

0.890

High

624826

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

4

9

Small-scale

0.890

High

624865

TF2B
Transcription initiation factor IIB

3

5

Small-scale

0.866

High

584544

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

3

8

Small-scale

0.827

High

625018

MED18
Mediator of RNA polymerase II transcription subunit 18

3

0

High-throughput

0.827

High

624779

T2EA
General transcription factor IIE subunit 1

2

1

Small-scale

0.806

High

270480

MED6
Mediator of RNA polymerase II transcription subunit 6

2

3

High-throughput

0.789

High

625109

MED31
Mediator of RNA polymerase II transcription subunit 31

2

0

High-throughput

0.770

High

624814

CDK9
Cyclin-dependent kinase 9

24

12

Small-scale

0.767

High

624813

CDK7
Cyclin-dependent kinase 7

12

8

Small-scale

0.759

High

624798

BRCA1
Breast cancer type 1 susceptibility protein

12

4

Small-scale

0.757

High

295496

RECQ5
ATP-dependent DNA helicase Q5

8

9

Small-scale

0.753

High

625063

MED17
Mediator of RNA polymerase II transcription subunit 17

2

0

High-throughput

0.748

High

625069

PIHD1
PIH1 domain-containing protein 1

7

3

Small-scale

0.745

High

625059

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

6

17

Small-scale

0.739

High

625111

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

6

7

Small-scale

0.738

High

624806

CDK8
Cyclin-dependent kinase 8

6

11

Small-scale

0.727

High

624871

ERCC6
DNA excision repair protein ERCC-6

6

12

Small-scale

0.719

High

48618

MED19
Mediator of RNA polymerase II transcription subunit 19

7

0

High-throughput

0.718

High

624961

PAF1
RNA polymerase II-associated factor 1 homolog

5

2

Small-scale

0.711

High

295592

RMP
Unconventional prefoldin RPB5 interactor 1

5

2

Small-scale

0.706

High

624888

MED21
Mediator of RNA polymerase II transcription subunit 21

6

0

Small-scale

0.702

High

625082

UXT
Protein UXT

4

2

High-throughput

0.699

High

589780

TBP
TATA-box-binding protein

4

4

Small-scale

0.698

High

624775

IKBA
NF-kappa-B inhibitor alpha

4

1

Small-scale

0.697

High

206606

MED7
Mediator of RNA polymerase II transcription subunit 7

1

3

High-throughput

0.691

High

624853

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

4

11

Small-scale

0.689

High

386118

P53
Cellular tumor antigen p53

1

0

Small-scale

0.687

High

625035

MED28
Mediator of RNA polymerase II transcription subunit 28

5

0

High-throughput

0.684

High

624883

ERCC8
DNA excision repair protein ERCC-8

4

5

Small-scale

0.680

High

624932

CDC73
Parafibromin

4

2

Small-scale

0.680

High

369005

ESR1
Estrogen receptor

4

5

Small-scale

0.676

High

624805

YAP1
Transcriptional coactivator YAP1

4

15

Small-scale

0.676

High

624873

DHX9
ATP-dependent RNA helicase A

4

2

Small-scale

0.676

High

624785

TF2H1
General transcription factor IIH subunit 1

5

0

Small-scale

0.674

High

624804

NEDD4
E3 ubiquitin-protein ligase NEDD4

3

10

Small-scale

0.667

High

125161

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

3

10

High-throughput

0.667

High

624816

SMCA4
Transcription activator BRG1

4

8

Small-scale

0.666

High

624879

CSTF3
Cleavage stimulation factor subunit 3

3

4

Small-scale

0.664

High

624867

HNRPU
Heterogeneous nuclear ribonucleoprotein U

3

3

Small-scale

0.664

High

624884

TIF1B
Transcription intermediary factor 1-beta

3

2

Small-scale

0.664

High

625068

MED9
Mediator of RNA polymerase II transcription subunit 9

4

0

High-throughput

0.664

High

571313

DDX5
Probable ATP-dependent RNA helicase DDX5

3

3

Small-scale

0.662

High

624799

VHL
von Hippel-Lindau disease tumor suppressor

4

0

Small-scale

0.656

High

243948

BRD4
Bromodomain-containing protein 4

3

11

High-throughput

0.656

High

345955

MYC
Myc proto-oncogene protein

3

4

High-throughput

0.656

High

624907

MED1
Mediator of RNA polymerase II transcription subunit 1

3

2

Small-scale

0.656

High

625054

GPN1
GPN-loop GTPase 1

3

9

High-throughput

0.656

High

624872

CSTF1
Cleavage stimulation factor subunit 1

3

5

Small-scale

0.651

High

624935

CTR9
RNA polymerase-associated protein CTR9 homolog

3

1

Small-scale

0.650

High

624772

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

11

Small-scale

0.647

High

624945

SPT6H
Transcription elongation factor SPT6

3

5

Small-scale

0.646

High

624875

EP300
Histone acetyltransferase p300

3

7

Small-scale

0.640

High

624809

CTCF
Transcriptional repressor CTCF

2

1

Small-scale

0.639

High

624857

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

2

5

Small-scale

0.639

High

625039

CAPAM
mRNA

2

1

Small-scale

0.639

High

313394

MED26
Mediator of RNA polymerase II transcription subunit 26

3

0

High-throughput

0.638

High

625017

MED10
Mediator of RNA polymerase II transcription subunit 10

3

0

High-throughput

0.638

High

624838

ACTB
Actin, cytoplasmic 1

3

0

Small-scale

0.636

High

624860

CSK21
Casein kinase II subunit alpha

3

10

Small-scale

0.635

High

624936

WDR82
WD repeat-containing protein 82

3

10

Small-scale

0.631

High

624874

SSRP1
FACT complex subunit SSRP1

2

10

Small-scale

0.628

High

625004

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

15

Small-scale

0.628

High

625046

MED20
Mediator of RNA polymerase II transcription subunit 20

3

0

High-throughput

0.628

High

625058

MED4
Mediator of RNA polymerase II transcription subunit 4

3

0

High-throughput

0.628

High

154747

TCRG1
Transcription elongation regulator 1

2

7

Small-scale

0.624

High

624778

ERCC5
DNA excision repair protein ERCC-5

2

1

Small-scale

0.624

High

624870

KMT2A
Histone-lysine N-methyltransferase 2A

2

11

Small-scale

0.624

High

624979

KAT2B
Histone acetyltransferase KAT2B

2

8

Small-scale

0.624

High

624998

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

10

High-throughput

0.624

High

625023

SETD2
Histone-lysine N-methyltransferase SETD2

2

10

Small-scale

0.624

High

625037

NELFA
Negative elongation factor A

2

1

Small-scale

0.624

High

625044

TDRD3
Tudor domain-containing protein 3

2

0

Small-scale

0.618

High

155994

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

11

High-throughput

0.618

High

169797

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

18

High-throughput

0.618

High

270181

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

3

High-throughput

0.618

High

317075

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

11

High-throughput

0.618

High

625026

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

3

High-throughput

0.618

High

625049

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

20

High-throughput

0.618

High

625067

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

20

High-throughput

0.618

High

625076

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

20

High-throughput

0.618

High

625110

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

12

High-throughput

0.618

High

624929

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

4

2

High-throughput

0.617

High

473893

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

3

1

High-throughput

0.611

High

225347

MED14
Mediator of RNA polymerase II transcription subunit 14

2

7

High-throughput

0.611

High

246536

MCE1
mRNA-capping enzyme

2

7

High-throughput

0.611

High

446508

SNRPA
U1 small nuclear ribonucleoprotein A

2

4

High-throughput

0.611

High

624793

FUS
RNA-binding protein FUS

2

9

High-throughput

0.611

High

624892

CUL2
Cullin-2

2

3

High-throughput

0.611

High

624982

CUL5
Cullin-5

2

3

High-throughput

0.611

High

624989

ARMC5
Armadillo repeat-containing protein 5

2

2

High-throughput

0.611

High

625030

XRN2
5'-3' exoribonuclease 2

2

1

Small-scale

0.611

High

625106

RUVB2
RuvB-like 2

2

9

High-throughput

0.611

High

625088

GPN3
GPN-loop GTPase 3

3

9

High-throughput

0.609

High

624819

CCNH
Cyclin-H

2

5

Small-scale

0.602

High

624876

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

2

3

Small-scale

0.602

High

624774

RBTN2
Rhombotin-2

2

0

High-throughput

0.602

High

624992

CPNE2
Copine-2

2

0

High-throughput

0.602

High

625010

INT14
Integrator complex subunit 14

2

0

High-throughput

0.602

High

625071

MED29
Mediator of RNA polymerase II transcription subunit 29

2

0

High-throughput

0.602

High

625055

SYF1
Pre-mRNA-splicing factor SYF1

2

5

Small-scale

0.601

High

153574

ANM5
Protein arginine N-methyltransferase 5

1

2

Small-scale

0.597

High

624897

ELOA1
Elongin-A

2

2

Small-scale

0.595

High

625013

BARD1
BRCA1-associated RING domain protein 1

2

2

Small-scale

0.595

High

277474

CCNK
Cyclin-K

2

5

Small-scale

0.594

High

624906

TAF11
Transcription initiation factor TFIID subunit 11

2

0

Small-scale

0.592

High

448552

RU1C
U1 small nuclear ribonucleoprotein C

2

0

High-throughput

0.585

High

538839

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

0

High-throughput

0.585

High

624933

MED27
Mediator of RNA polymerase II transcription subunit 27

2

0

High-throughput

0.585

High

624993

MED8
Mediator of RNA polymerase II transcription subunit 8

2

0

High-throughput

0.585

High

624997

MED30
Mediator of RNA polymerase II transcription subunit 30

2

0

Small-scale

0.585

High

625075

MED11
Mediator of RNA polymerase II transcription subunit 11

2

0

High-throughput

0.585

High

624971

LEO1
RNA polymerase-associated protein LEO1

2

2

Small-scale

0.585

High

625090

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

2

4

Small-scale

0.585

High

625041

RPAP3
RNA polymerase II-associated protein 3

3

7

High-throughput

0.585

High

124166

TAF4
Transcription initiation factor TFIID subunit 4

2

4

Small-scale

0.584

High

517060

PCNA
Proliferating cell nuclear antigen

2

1

Small-scale

0.584

High

555298

H2AX
Histone H2AX

2

6

Small-scale

0.584

High

569204

CEBPB
CCAAT/enhancer-binding protein beta

2

2

Small-scale

0.584

High

624777

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

3

Small-scale

0.584

High

624831

TERA
Transitional endoplasmic reticulum ATPase

2

4

Small-scale

0.584

High

624850

H4
Histone H4

2

4

High-throughput

0.584

High

624854

RBX1
E3 ubiquitin-protein ligase RBX1

2

1

Small-scale

0.584

High

624882

CBX3
Chromobox protein homolog 3

2

3

Small-scale

0.584

High

624893

CUL3
Cullin-3

2

3

High-throughput

0.584

High

624910

DDB1
DNA damage-binding protein 1

2

3

Small-scale

0.584

High

624977

CBP
CREB-binding protein

2

6

Small-scale

0.584

High

625092

INT6
Integrator complex subunit 6

2

1

Small-scale

0.584

High

625093

AGO1
Protein argonaute-1

2

6

Small-scale

0.584

High

624914

SMN
Survival motor neuron protein

1

0

Small-scale

0.583

High

625074

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.582

High

624820

MAT1
CDK-activating kinase assembly factor MAT1

2

0

Small-scale

0.577

High

182087

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

4

High-throughput

0.571

High

534060

T2FB
General transcription factor IIF subunit 2

2

2

Small-scale

0.571

High

624788

MCM7
DNA replication licensing factor MCM7

2

1

Small-scale

0.571

High

122500

MEN1
Menin

2

0

Small-scale

0.569

High

624786

CSTF2
Cleavage stimulation factor subunit 2

1

4

Small-scale

0.561

High

624881

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

3

Small-scale

0.561

High

624885

SKP2
S-phase kinase-associated protein 2

1

1

High-throughput

0.561

High

625001

NSD1
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

12

Small-scale

0.561

High

625016

WAC
WW domain-containing adapter protein with coiled-coil

1

1

Small-scale

0.561

High

625099

PHF8
Histone lysine demethylase PHF8

1

5

Small-scale

0.561

High

624901

CUL7
Cullin-7

2

0

High-throughput

0.559

High

624908

TRIP4
Activating signal cointegrator 1

2

0

High-throughput

0.559

High

624919

UVSSA
UV-stimulated scaffold protein A

2

0

Small-scale

0.559

High

624947

SETX
Probable helicase senataxin

1

5

Small-scale

0.554

High

624836

ELOF1
Transcription elongation factor 1 homolog

1

1

Small-scale

0.553

High

624815

SMCA2
Probable global transcription activator SNF2L2

2

8

Small-scale

0.552

High

625056

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

2

Small-scale

0.550

High

624999

NEUL4
Neuralized-like protein 4

2

0

Small-scale

0.547

High

624899

MDC1
Mediator of DNA damage checkpoint protein 1

2

0

Small-scale

0.539

High

241859

PQBP1
Polyglutamine-binding protein 1

1

0

Small-scale

0.537

High

507370

ERG
Transcriptional regulator ERG

1

0

Small-scale

0.537

High

524795

XRCC5
X-ray repair cross-complementing protein 5

1

0

Small-scale

0.537

High

528360

MYH6
Myosin-6

1

0

Small-scale

0.537

High

559559

H12
Histone H1.2

1

0

Small-scale

0.537

High

624911

ZNF74
Zinc finger protein 74

1

0

Small-scale

0.537

High

624946

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

Small-scale

0.537

High

624994

OTUD5
OTU domain-containing protein 5

1

0

Small-scale

0.537

High

181681

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

3

High-throughput

0.536

High

449544

HMGB1
High mobility group protein B1

1

9

High-throughput

0.536

High

624832

NH2L1
NHP2-like protein 1

1

2

High-throughput

0.536

High

624845

RUXF
Small nuclear ribonucleoprotein F

1

2

High-throughput

0.536

High

624863

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.536

High

624903

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

624912

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

8

High-throughput

0.536

High

624915

MK06
Mitogen-activated protein kinase 6

1

6

High-throughput

0.536

High

624917

H2B2E
Histone H2B type 2-E

1

11

High-throughput

0.536

High

624921

ZN326
DBIRD complex subunit ZNF326

1

1

Small-scale

0.536

High

624959

ARRD1
Arrestin domain-containing protein 1

1

6

High-throughput

0.536

High

624964

ARRD4
Arrestin domain-containing protein 4

1

6

High-throughput

0.536

High

624969

ARRD2
Arrestin domain-containing protein 2

1

6

High-throughput

0.536

High

624988

ARRD3
Arrestin domain-containing protein 3

1

6

High-throughput

0.536

High

624990

HDA11
Histone deacetylase 11

1

2

High-throughput

0.536

High

625014

EPAS1
Endothelial PAS domain-containing protein 1

1

1

High-throughput

0.536

High

625031

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

10

High-throughput

0.536

High

625034

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

2

High-throughput

0.536

High

625036

TXNIP
Thioredoxin-interacting protein

1

6

High-throughput

0.536

High

625047

WDR76
WD repeat-containing protein 76

1

8

High-throughput

0.536

High

625003

DAA10
Dynein axonemal assembly factor 10

2

2

High-throughput

0.533

High

625077

PHRF1
PHD and RING finger domain-containing protein 1

2

2

Small-scale

0.533

High

624877

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

2

0

Small-scale

0.528

High

624976

TF2H4
General transcription factor IIH subunit 4

1

0

Small-scale

0.527

High

624958

SH2D3
SH2 domain-containing protein 3C

2

4

High-throughput

0.521

High

146596

SOCS2
Suppressor of cytokine signaling 2

1

5

High-throughput

0.515

High

147486

SOCS6
Suppressor of cytokine signaling 6

1

5

High-throughput

0.515

High

305728

ELP1
Elongator complex protein 1

1

1

Small-scale

0.515

High

203874

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.513

High

234647

BRNP1
BMP/retinoic acid-inducible neural-specific protein 1

1

0

Small-scale

0.513

High

508343

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

556782

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.513

High

564803

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.513

High

624808

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

624864

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

624944

MED25
Mediator of RNA polymerase II transcription subunit 25

1

0

High-throughput

0.513

High

624952

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

624987

SOSB2
SOSS complex subunit B2

1

0

High-throughput

0.513

High

624995

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

624856

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.508

High

149968

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

7

Small-scale

0.501

High

152591

KMT2D
Histone-lysine N-methyltransferase 2D

1

15

Small-scale

0.501

High

236697

CCNT1
Cyclin-T1

1

5

Small-scale

0.501

High

509903

VDR
Vitamin D3 receptor

1

4

Small-scale

0.501

High

624776

U2AF2
Splicing factor U2AF 65 kDa subunit

1

2

Small-scale

0.501

High

624787

TTK
Dual specificity protein kinase TTK

1

1

Small-scale

0.501

High

624837

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

High-throughput

0.501

High

624841

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.501

High

624843

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

8

Small-scale

0.501

High

624859

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

2

Small-scale

0.501

High

624904

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

4

Small-scale

0.501

High

625009

IWS1
Protein IWS1 homolog

1

2

Small-scale

0.501

High

625028

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

7

Small-scale

0.501

High

625052

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

10

Small-scale

0.501

High

625078

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

2

Small-scale

0.501

High

625079

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

4

Small-scale

0.501

High

625097

PRP19
Pre-mRNA-processing factor 19

1

5

Small-scale

0.501

High

625098

CC14A
Dual specificity protein phosphatase CDC14A

1

5

Small-scale

0.501

High

625072

CDK12
Cyclin-dependent kinase 12

1

11

Small-scale

0.500

High

625102

DICER
Endoribonuclease Dicer

1

5

Small-scale

0.500

High

624996

SNF8
Vacuolar-sorting protein SNF8

1

0

Small-scale

0.493

High

624956

MIER1
Mesoderm induction early response protein 1

1

0

High-throughput

0.493

High

624970

THAP3
THAP domain-containing protein 3

1

0

High-throughput

0.493

High

624895

DPYL1
Dihydropyrimidinase-related protein 1

1

2

High-throughput

0.489

High

624896

DPYL3
Dihydropyrimidinase-related protein 3

1

2

High-throughput

0.489

High

624991

RMC1
Regulator of MON1-CCZ1 complex

1

1

High-throughput

0.489

High

625002

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.489

High

625008

TCPQM
T-complex protein 1 subunit theta-like 2

1

1

High-throughput

0.489

High

625011

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.489

High

625083

FBLN5
Fibulin-5

1

2

High-throughput

0.489

High

624827

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

Small-scale

0.480

High

624886

ATM
Serine-protein kinase ATM

1

0

Small-scale

0.480

High

154655

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

7

Small-scale

0.479

High

165628

SET1A
Histone-lysine N-methyltransferase SETD1A

1

11

Small-scale

0.479

High

179550

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

212105

HTSF1
17S U2 SnRNP complex component HTATSF1

1

9

Small-scale

0.479

High

217444

AIRE
Autoimmune regulator

1

4

Small-scale

0.479

High

226556

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

232784

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.479

High

241452

H2B1K
Histone H2B type 1-K

1

11

High-throughput

0.479

High

255512

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.479

High

266313

TAD2A
Transcriptional adapter 2-alpha

1

4

High-throughput

0.479

High

267895

EED
Polycomb protein EED

1

5

High-throughput

0.479

High

294381

RECQ4
ATP-dependent DNA helicase Q4

1

10

High-throughput

0.479

High

300401

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

2

Small-scale

0.479

High

304587

SCAF4
SR-related and CTD-associated factor 4

1

4

High-throughput

0.479

High

337953

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

384286

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

402711

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

3

High-throughput

0.479

High

420805

H2B1J
Histone H2B type 1-J

1

11

High-throughput

0.479

High

441886

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

7

High-throughput

0.479

High

518254

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.479

High

551974

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

560858

GBB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

1

6

Small-scale

0.479

High

577727

NELFE
Negative elongation factor E

1

1

Small-scale

0.479

High

598425

NF1
Neurofibromin

1

1

Small-scale

0.479

High

612460

XPA
DNA repair protein complementing XP-A cells

1

1

Small-scale

0.479

High

624396

CCNC
Cyclin-C

1

5

High-throughput

0.479

High

624773

MCM3
DNA replication licensing factor MCM3

1

2

Small-scale

0.479

High

624780

T2EB
Transcription initiation factor IIE subunit beta

1

2

Small-scale

0.479

High

624784

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

624789

CTNB1
Catenin beta-1

1

1

High-throughput

0.479

High

624791

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

624794

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

High-throughput

0.479

High

624796

SRBP1
Sterol regulatory element-binding protein 1

1

2

Small-scale

0.479

High

624800

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

624802

RAD52
DNA repair protein RAD52 homolog

1

1

Small-scale

0.479

High

624807

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

4

High-throughput

0.479

High

624821

NCBP2
Nuclear cap-binding protein subunit 2

1

2

High-throughput

0.479

High

624825

ZN131
Zinc finger protein 131

1

1

High-throughput

0.479

High

624828

HIRA
Protein HIRA

1

3

Small-scale

0.479

High

624833

CTBP2
C-terminal-binding protein 2

1

2

High-throughput

0.479

High

624834

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

2

High-throughput

0.479

High

624835

H2B1D
Histone H2B type 1-D

1

11

High-throughput

0.479

High

624844

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

624846

SMD1
Small nuclear ribonucleoprotein Sm D1

1

2

High-throughput

0.479

High

624848

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.479

High

624851

H2B1C
Histone H2B type 1-C/E/F/G/I

1

11

High-throughput

0.479

High

624852

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

6

Small-scale

0.479

High

624855

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

7

Small-scale

0.479

High

624858

CSK2B
Casein kinase II subunit beta

1

1

High-throughput

0.479

High

624861

H31
Histone H3.1

1

6

High-throughput

0.479

High

624868

EWS
RNA-binding protein EWS

1

5

Small-scale

0.479

High

624869

ENL
Protein ENL

1

3

Small-scale

0.479

High

624878

TAF10
Transcription initiation factor TFIID subunit 10

1

1

Small-scale

0.479

High

624887

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

624889

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

Small-scale

0.479

High

624891

CUL1
Cullin-1

1

3

High-throughput

0.479

High

624894

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

3

Small-scale

0.479

High

624898

RBM39
RNA-binding protein 39

1

3

High-throughput

0.479

High

624900

SMC1A
Structural maintenance of chromosomes protein 1A

1

2

Small-scale

0.479

High

624902

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

624909

EZH2
Histone-lysine N-methyltransferase EZH2

1

13

Small-scale

0.479

High

624916

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

624923

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

1

High-throughput

0.479

High

624924

INT11
Integrator complex subunit 11

1

4

Small-scale

0.479

High

624925

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

10

High-throughput

0.479

High

624926

RN123
E3 ubiquitin-protein ligase RNF123

1

3

High-throughput

0.479

High

624930

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

624937

MCAF1
Activating transcription factor 7-interacting protein 1

1

2

Small-scale

0.479

High

624939

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

624943

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

1

High-throughput

0.479

High

624948

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

3

High-throughput

0.479

High

624950

THOC4
THO complex subunit 4

1

3

Small-scale

0.479

High

624955

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

624960

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.479

High

624965

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

624973

PSPC1
Paraspeckle component 1

1

3

High-throughput

0.479

High

624978

RBP56
TATA-binding protein-associated factor 2N

1

5

Small-scale

0.479

High

624980

DDX17
Probable ATP-dependent RNA helicase DDX17

1

3

High-throughput

0.479

High

624983

MED12
Mediator of RNA polymerase II transcription subunit 12

1

1

High-throughput

0.479

High

624984

H2B1H
Histone H2B type 1-H

1

11

High-throughput

0.479

High

624985

FBXW7
F-box/WD repeat-containing protein 7

1

5

High-throughput

0.479

High

625000

EGLN2
Prolyl hydroxylase EGLN2

1

3

Small-scale

0.479

High

625006

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

625007

CCNL2
Cyclin-L2

1

5

Small-scale

0.479

High

625015

H2B1L
Histone H2B type 1-L

1

9

High-throughput

0.479

High

625020

CDK19
Cyclin-dependent kinase 19

1

12

High-throughput

0.479

High

625027

EGLN1
Egl nine homolog 1

1

3

Small-scale

0.479

High

625029

WWTR1
WW domain-containing transcription regulator protein 1

1

13

High-throughput

0.479

High

625033

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

625038

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

625042

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

625043

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

2

Small-scale

0.479

High

625045

SFR19
Splicing factor, arginine/serine-rich 19

1

4

High-throughput

0.479

High

625051

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

7

Small-scale

0.479

High

625053

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

4

Small-scale

0.479

High

625061

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

625062

PDRG1
p53 and DNA damage-regulated protein 1

1

2

High-throughput

0.479

High

625065

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

3

High-throughput

0.479

High

625081

DNM3B
DNA

1

2

Small-scale

0.479

High

625084

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

625086

MED13
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.479

High

625087

PFD2
Prefoldin subunit 2

1

3

High-throughput

0.479

High

625089

BAZ1B
Tyrosine-protein kinase BAZ1B

1

12

Small-scale

0.479

High

625091

AGO2
Protein argonaute-2

1

6

Small-scale

0.479

High

625096

MYO6
Unconventional myosin-VI

1

2

Small-scale

0.479

High

625100

SET1B
Histone-lysine N-methyltransferase SETD1B

1

12

Small-scale

0.479

High

625103

SMC3
Structural maintenance of chromosomes protein 3

1

2

Small-scale

0.479

High

625108

FBW1A
F-box/WD repeat-containing protein 1A

1

5

High-throughput

0.479

High

625112

CABIN
Calcineurin-binding protein cabin-1

1

2

Small-scale

0.479

High

625113

DNM3A
DNA

1

1

Small-scale

0.479

High

625085

ZNHI2
Zinc finger HIT domain-containing protein 2

1

1

High-throughput

0.470

High

625060

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

61308

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

Small-scale

0.458

High

162417

XPO1
Exportin-1

1

0

High-throughput

0.458

High

209682

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

214852

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

Small-scale

0.458

High

319122

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

351260

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

396887

HMGN1
Non-histone chromosomal protein HMG-14

1

0

Small-scale

0.458

High

434562

ERCC1
DNA excision repair protein ERCC-1

1

0

Small-scale

0.458

High

574124

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

1

0

Small-scale

0.458

High

624781

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

0

Small-scale

0.458

High

624782

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.458

High

624790

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

624797

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

624801

HD
Huntingtin

1

0

Small-scale

0.458

High

624803

MAGAB
Melanoma-associated antigen 11

1

0

Small-scale

0.458

High

624811

DNLI3
DNA ligase 3

1

0

Small-scale

0.458

High

624812

CDN1C
Cyclin-dependent kinase inhibitor 1C

1

0

Small-scale

0.458

High

624817

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

624829

ATX3
Ataxin-3

1

0

Small-scale

0.458

High

624842

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

Small-scale

0.458

High

624847

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

624862

GTF2I
General transcription factor II-I

1

0

Small-scale

0.458

High

624866

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

624880

CSN1
COP9 signalosome complex subunit 1

1

0

Small-scale

0.458

High

624905

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.458

High

624920

PHLA2
Pleckstrin homology-like domain family A member 2

1

0

High-throughput

0.458

High

624928

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

624931

TECT3
Tectonic-3

1

0

High-throughput

0.458

High

624934

INT5
Integrator complex subunit 5

1

0

High-throughput

0.458

High

624938

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

1

0

Small-scale

0.458

High

624949

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

624957

INT1
Integrator complex subunit 1

1

0

High-throughput

0.458

High

624962

SCAI
Protein SCAI

1

0

Small-scale

0.458

High

624967

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

624968

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

624972

NELFB
Negative elongation factor B

1

0

Small-scale

0.458

High

624981

XPF
DNA repair endonuclease XPF

1

0

Small-scale

0.458

High

624986

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

625005

QKI
KH domain-containing RNA-binding protein QKI

1

0

High-throughput

0.458

High

625012

PNKP
Bifunctional polynucleotide phosphatase/kinase

1

0

Small-scale

0.458

High

625019

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

625022

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

625024

IN80B
INO80 complex subunit B

1

0

High-throughput

0.458

High

625040

STN1
CST complex subunit STN1

1

0

High-throughput

0.458

High

625057

UBN1
Ubinuclein-1

1

0

Small-scale

0.458

High

625064

INT10
Integrator complex subunit 10

1

0

Small-scale

0.458

High

625080

MBD2
Methyl-CpG-binding domain protein 2

1

0

Small-scale

0.458

High

625094

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

625105

RTRAF
RNA transcription, translation and transport factor protein

1

0

Small-scale

0.458

High

625114

NS1BP
Influenza virus NS1A-binding protein

1

0

Small-scale

0.458

High

624810

MCM2
DNA replication licensing factor MCM2

1

2

Small-scale

0.445

High

624824

T2AG
Transcription initiation factor IIA subunit 2

1

1

Small-scale

0.445

High

624974

RTF1
RNA polymerase-associated protein RTF1 homolog

1

1

Small-scale

0.445

High

625032

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.445

High

625050

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.445

High

625095

AKP8L
A-kinase anchor protein 8-like

1

1

High-throughput

0.445

High

148411

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.437

High

624818

AFF1
AF4/FMR2 family member 1

1

2

Small-scale

0.437

High

624830

HAP1
Huntingtin-associated protein 1

1

1

Small-scale

0.437

High

624927

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.437

High

624940

CE128
Centrosomal protein of 128 kDa

1

3

High-throughput

0.437

High

625021

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

1

High-throughput

0.437

High

625066

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

Small-scale

0.437

High

320977

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

624839

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.426

High

624890

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

625025

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

625048

ELP3
Elongator complex protein 3

1

0

Small-scale

0.426

High

625101

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

3

Small-scale

0.408

High

473851

MYZAP
Myocardial zonula adherens protein

1

3

High-throughput

0.407

High

625070

ASB6
Ankyrin repeat and SOCS box protein 6

4

0

High-throughput

0.364

High

624942

SYDE1
Rho GTPase-activating protein SYDE1

2

0

High-throughput

0.328

High

624918

SAMTR
S-adenosylmethionine sensor upstream of mTORC1

1

0

High-throughput

0.279

Low

624922

FREM2
FRAS1-related extracellular matrix protein 2

1

0

High-throughput

0.279

Low

624966

GP156
Probable G-protein coupled receptor 156

1

0

High-throughput

0.279

Low

624975

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

625104

COLQ
Acetylcholinesterase collagenic tail peptide

1

0

High-throughput

0.279

Low

624953

PKHL1
Fibrocystin-L

1

0

High-throughput

0.269

Low

624963

FSIP1
Fibrous sheath-interacting protein 1

1

0

High-throughput

0.269

Low

624951

IFTAP
Intraflagellar transport-associated protein

1

0

Small-scale

0.265

Low

208528

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.249

Low

329370

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

393041

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.249

Low

483626

CSH2
Chorionic somatomammotropin hormone 2

1

0

Small-scale

0.249

Low

624913

TAZ
Tafazzin

1

0

Small-scale

0.249

Low

624941

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

625073

USE1
Vesicle transport protein USE1

1

0

Small-scale

0.232

Low

625107

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024