HitPredict

Interactor 1: SRC8 (Q14247)
Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Gene: CTTN

Interactor 2: CT2NL (Q9P2B4)
CTTNBP2 N-terminal-like protein
Gene: CTTNBP2NL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030027 - lamellipodium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 550 Hs			1 639
+	Hs
		1052272 SRC8_HUMAN (1-550): 0: 559: 100.00		CTTB2_HUMAN (1-639): 1.57e-58: 215: 38.46
+	Hs
		1052245 SRC8_HUMAN (1-550): 0: 559: 100.00		LUZP1_HUMAN (4-486): 5.63e-35: 144: 15.93
+	Hs
		1052202 SRC8_HUMAN (1-550): 0: 559: 100.00		PLEC_HUMAN (110-303): 6.93e-11: 68.1: 19.49
+	Hs
		724825 SRC8_HUMAN (1-550): 0: 559: 100.00		MYH9_HUMAN (1-396): 1.07e-09: 64: 12.53
+	Hs
		724801 MYO1E_HUMAN (165-549): 3.1e-44: 170: 15.01		MYH9_HUMAN (1-396): 1.07e-09: 64: 12.53
+	Hs
		547279 PACN2_HUMAN (176-550): 4.93e-40: 153: 15.37		EZRI_HUMAN (122-289): 3.32e-10: 65: 18.82
+	Hs
		1045418 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		PLEC_HUMAN (110-303): 6.93e-11: 68.1: 19.49
+	Hs
		547044 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		EZRI_HUMAN (122-289): 3.32e-10: 65: 18.82
+	Hs
		522612 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		MYH7_HUMAN (3-329): 9.35e-10: 64: 12.39
+	Hs
		724817 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		MYH9_HUMAN (1-396): 1.07e-09: 64: 12.53
+	Hs
		1045423 SPTN1_HUMAN (213-549): 1.51e-33: 138: 14.12		ITSN1_HUMAN (99-632): 3.95e-09: 62.1: 9.34
+	Hs
		1078900 SH3G2_HUMAN (365-549): 1.87e-31: 126: 17.28		ITSN1_HUMAN (99-632): 3.95e-09: 62.1: 9.34
+	Hs
		787985 ITSN2_HUMAN (398-548): 1.14e-18: 92.3: 17.88		EPS15_HUMAN (20-551): 3.8e-10: 65.2: 10.90
+	Hs
		547250 ITSN2_HUMAN (398-548): 1.14e-18: 92.3: 17.88		EZRI_HUMAN (122-289): 3.32e-10: 65: 18.82
+	Hs
		61732 A6H8W8_HUMAN (398-548): 1.72e-18: 91.9: 17.88		EPS15_HUMAN (20-551): 3.8e-10: 65.2: 10.90
+	Hs
		1078919 ITSN2_HUMAN (398-548): 1.14e-18: 92.3: 17.88		ITSN1_HUMAN (99-632): 3.95e-09: 62.1: 9.34
+	Hs
		787920 ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99		EPS15_HUMAN (20-551): 3.8e-10: 65.2: 10.90
+	Hs
		547074 ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99		EZRI_HUMAN (122-289): 3.32e-10: 65: 18.82
+	Cl
		47357 F1PHV6_CANLF (274-548): 7.81e-14: 77: 11.46		A0A8I3PJA6_CANLF (1-183): 2.79e-10: 65.5: 15.30
+	Hs
		1078828 ITSN1_HUMAN (165-548): 1.66e-14: 78.9: 11.99		ITSN1_HUMAN (99-632): 3.95e-09: 62.1: 9.34