HitPredict

Interactor 1: TRI25 (Q14258)
E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147)
Gene: TRIM25

Interactor 2: UB2J1 (Q9Y385)
Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e)
Gene: UBE2J1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36567344
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0036503 - ERAD pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 630 Hs			1 318
+	Hs
		1052807 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		UB2D4_HUMAN (10-156): 3.97e-70: 216: 28.00
+	Hs
		919727 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		849330 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		895794 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		1052708 TRI25_HUMAN (1-630): 3.52e-149: 447: 100.00		UB2J2_HUMAN (1-150): 3.16e-63: 202: 39.87
+	Hs
		175664 TRI18_HUMAN (4-629): 4.7e-124: 383: 22.17		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		175730 TRI18_HUMAN (4-629): 4.7e-124: 383: 22.17		UB2D4_HUMAN (10-156): 3.97e-70: 216: 28.00
+	Hs
		175653 TRI18_HUMAN (4-629): 4.7e-124: 383: 22.17		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		175658 TRI18_HUMAN (4-629): 4.7e-124: 383: 22.17		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		175654 TRI18_HUMAN (4-629): 4.7e-124: 383: 22.17		UB2E1_HUMAN (1-156): 1.67e-64: 203: 28.30
+	Hs
		1151762 Q6GX22_HUMAN (4-629): 2.93e-118: 368: 21.72		UB2D4_HUMAN (10-156): 3.97e-70: 216: 28.00
+	Hs
		175703 TRI18_HUMAN (4-629): 4.7e-124: 383: 22.17		UB2E3_HUMAN (2-156): 9.16e-63: 199: 26.58
+	Hs
		175710 TRI18_HUMAN (4-629): 4.7e-124: 383: 22.17		UB2E2_HUMAN (2-156): 2.19e-62: 198: 27.22
+	Hs
		1356055 TRIM1_HUMAN (3-629): 8.74e-115: 361: 20.58		UB2D4_HUMAN (10-156): 3.97e-70: 216: 28.00
+	Hs
		919896 TRIM1_HUMAN (3-629): 8.74e-115: 361: 20.58		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		849480 TRIM1_HUMAN (3-629): 8.74e-115: 361: 20.58		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		895945 TRIM1_HUMAN (3-629): 8.74e-115: 361: 20.58		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		851905 TRIM1_HUMAN (3-629): 8.74e-115: 361: 20.58		UB2E1_HUMAN (1-156): 1.67e-64: 203: 28.30
+	Hs
		1282363 TRIM1_HUMAN (3-629): 8.74e-115: 361: 20.58		UB2E3_HUMAN (2-156): 9.16e-63: 199: 26.58
+	Hs
		1297378 TRIM1_HUMAN (3-629): 8.74e-115: 361: 20.58		UB2E2_HUMAN (2-156): 2.19e-62: 198: 27.22