HitPredict

Interactor 1: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Interactor 2: SPDLY (Q96EA4)
Protein Spindly (hSpindly) (Arsenite-related gene 1 protein) (Coiled-coil domain-containing protein 99) (Rhabdomyosarcoma antigen MU-RMS-40.4A) (Spindle apparatus coiled-coil domain-containing protein 1)
Gene: SPDL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30258100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2725 Hs			1 605
+	Hs
		598271 FLNA_HUMAN (167-2725): 0: 1226: 35.27		SPDLY_HUMAN (1-605): 2.11e-78: 261: 100.00
+	Hs
		261309 FLNB_HUMAN (146-2725): 0: 1198: 35.18		SPDLY_HUMAN (1-605): 2.11e-78: 261: 100.00
+	Hs
		598391 FLNA_HUMAN (167-2725): 0: 1226: 35.27		MYO5A_HUMAN (5-568): 1.39e-35: 145: 12.21
+	Hs
		597985 FLNA_HUMAN (167-2725): 0: 1226: 35.27		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		597987 FLNA_HUMAN (167-2725): 0: 1226: 35.27		MYH11_HUMAN (14-535): 3.32e-14: 78.3: 12.27
+	Hs
		598255 FLNA_HUMAN (167-2725): 0: 1226: 35.27		MY18A_HUMAN (36-569): 9.74e-11: 67.1: 14.03
+	Hs
		261212 FLNB_HUMAN (146-2725): 0: 1198: 35.18		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		261303 FLNB_HUMAN (146-2725): 0: 1198: 35.18		MY18A_HUMAN (36-569): 9.74e-11: 67.1: 14.03
+	Hs
		963388 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		SPDLY_HUMAN (1-605): 2.11e-78: 261: 100.00
+	Hs
		521484 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		211515 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		211632 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		MY18A_HUMAN (36-569): 9.74e-11: 67.1: 14.03
+	Hs
		724781 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		963381 SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12		MY18A_HUMAN (36-569): 9.74e-11: 67.1: 14.03
+	Hs
		362883 FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		362884 FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Hs
		551790 TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78		DESP_HUMAN (15-507): 8.07e-47: 179: 14.37