HitPredict

Interactor 1: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Interactor 2: MYOZ1 (Q9NP98)
Myozenin-1 (Calsarcin-2) (Filamin-, actinin- and telethonin-binding protein) (Protein FATZ)
Gene: MYOZ1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	11842093, 11171996, 10984498
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030018 - Z disc GO:0045214 - sarcomere organization
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2725 Hs			1 299
+	Hs
		1052948 FLNC_HUMAN (1-2725): 0: 2507: 100.00		MYOZ2_HUMAN (6-282): 3.08e-122: 352: 34.30
+	Hs
		1052907 FLNC_HUMAN (1-2725): 0: 2507: 100.00		MYOZ3_HUMAN (12-276): 4.48e-76: 234: 27.37
+	Hs
		598333 FLNA_HUMAN (167-2725): 0: 1226: 35.27		MYOZ1_HUMAN (1-299): 3.74e-140: 398: 100.00
+	Hs
		521620 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		MYOZ1_HUMAN (1-299): 3.74e-140: 398: 100.00
+	Hs
		725701 ACTN2_HUMAN (2-387): 2.32e-122: 412: 26.00		MYOZ1_HUMAN (1-299): 3.74e-140: 398: 100.00
+	Hs
		211668 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		MYOZ1_HUMAN (1-299): 3.74e-140: 398: 100.00
+	Hs
		993297 ACTN3_HUMAN (23-388): 4.53e-120: 406: 27.63		MYOZ1_HUMAN (1-299): 3.74e-140: 398: 100.00
+	Hs
		521621 ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30		MYOZ2_HUMAN (6-282): 3.08e-122: 352: 34.30
+	Hs
		725702 ACTN2_HUMAN (2-387): 2.32e-122: 412: 26.00		MYOZ2_HUMAN (6-282): 3.08e-122: 352: 34.30
+	Hs
		211669 ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68		MYOZ2_HUMAN (6-282): 3.08e-122: 352: 34.30