Protein: RUXE
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)

Gene: RUXE, SME1
Organism: Saccharomyces cerevisiae S288C
Interactions: 61
UniProt ID: Q12330

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

933156

RUXF
Small nuclear ribonucleoprotein F

6

9

Small-scale

0.950

High

820852

RUXG
Small nuclear ribonucleoprotein G

5

13

Small-scale

0.927

High

1065582

RU2A
U2 small nuclear ribonucleoprotein A'

5

4

Small-scale

0.908

High

1054396

SMD2
Small nuclear ribonucleoprotein Sm D2

4

2

High-throughput

0.881

High

817182

RSMB
Small nuclear ribonucleoprotein-associated protein B

3

3

High-throughput

0.839

High

847846

SMD3
Small nuclear ribonucleoprotein Sm D3

3

17

Small-scale

0.839

High

751809

PRP8
Pre-mRNA-splicing factor 8

3

1

High-throughput

0.830

High

780239

SN114
Pre-mRNA-splicing factor SNU114

3

2

High-throughput

0.830

High

1036191

SMD1
Small nuclear ribonucleoprotein Sm D1

2

2

High-throughput

0.776

High

945362

LSM3
LSM complex subunit LSM3

2

16

Small-scale

0.768

High

625147

PRP9
Pre-mRNA-splicing factor PRP9

2

1

High-throughput

0.759

High

1059555

LUC7
Protein LUC7

2

0

High-throughput

0.716

High

1084786

RUXE
Small nuclear ribonucleoprotein E

1

2

Small-scale

0.710

High

1028004

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

3

High-throughput

0.665

High

744182

BRR2
Pre-mRNA-splicing helicase BRR2

4

5

Small-scale

0.659

High

1043517

CEF1
Pre-mRNA-splicing factor CEF1

3

2

Small-scale

0.650

High

625059

PRP6
Pre-mRNA-splicing factor 6

3

5

High-throughput

0.643

High

627881

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

3

3

High-throughput

0.643

High

743566

RU1A
U1 small nuclear ribonucleoprotein A

3

0

Small-scale

0.632

High

1052789

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.631

High

795945

LSM2
LSM complex subunit LSM2

1

13

Small-scale

0.621

High

1042462

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

1

High-throughput

0.618

High

750326

PRP40
Pre-mRNA-processing protein PRP40

2

2

High-throughput

0.601

High

886361

PRP31
Pre-mRNA-processing factor 31

2

1

High-throughput

0.601

High

892801

SF3B1
U2 snRNP component HSH155

2

2

High-throughput

0.588

High

1047398

RSE1
Pre-mRNA-splicing factor RSE1

2

1

High-throughput

0.588

High

1084787

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

1

Small-scale

0.584

High

590755

HSP26
Heat shock protein 26

2

0

High-throughput

0.563

High

757602

MED20
Mediator of RNA polymerase II transcription subunit 20

2

0

High-throughput

0.563

High

603124

EST1
Telomere elongation protein EST1

2

0

Small-scale

0.559

High

757558

NCBP1
Nuclear cap-binding protein complex subunit 1

2

0

Small-scale

0.559

High

1025667

NAM8
Protein NAM8

2

0

High-throughput

0.559

High

1065116

NCBP2
Nuclear cap-binding protein subunit 2

2

0

High-throughput

0.559

High

546790

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

628243

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

2

High-throughput

0.515

High

664633

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

2

Small-scale

0.501

High

1037767

CUS1
Cold sensitive U2 snRNA suppressor 1

1

1

High-throughput

0.479

High

1044046

PRP42
U1 small nuclear ribonucleoprotein component PRP42

1

7

High-throughput

0.479

High

1057087

DIB1
Spliceosomal protein DIB1

1

2

High-throughput

0.479

High

1084743

CLF1
Pre-mRNA-splicing factor CLF1

1

6

Small-scale

0.479

High

738943

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.458

High

780872

MUD2
Splicing factor MUD2

1

0

High-throughput

0.458

High

781595

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

797517

POP7
Ribonucleases P/MRP protein subunit POP7

1

0

Small-scale

0.458

High

918293

POP6
Ribonucleases P/MRP protein subunit POP6

1

0

Small-scale

0.458

High

1044070

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1053965

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.458

High

525584

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

739224

PRP19
Pre-mRNA-processing factor 19

1

3

Small-scale

0.445

High

742705

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

816475

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.445

High

820149

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

1052947

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

3

High-throughput

0.445

High

1084403

PER33
Pore and endoplasmic reticulum protein of 33 kDa

1

1

Small-scale

0.437

High

1084519

POM33
Pore membrane protein of 33 kDa

1

1

Small-scale

0.437

High

752896

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

370485

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

1

0

High-throughput

0.269

Low

924936

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.269

Low

1064909

RRG7
Required for respiratory growth protein 7, mitochondrial

1

0

High-throughput

0.269

Low

1084705

YOR97
Uncharacterized protein YOR097C

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025