HitPredict

Interactor 1: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Interactor 2: TAB3 (Q8N5C8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
Gene: TAB3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.649

Property	Details
Experiments	22081109, 21976705
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005829 - cytosol GO:0010008 - endosome membrane GO:0060090 - molecular adaptor activity
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 712
+	Mm
		291956 BECN1_MOUSE (1-450): 0: 633: 98.00		TAB3_MOUSE (1-712): 2.53e-96: 315: 94.69
+	Hs
		1054218 BECN1_HUMAN (1-450): 0: 645: 100.00		TAB2_HUMAN (1-711): 6.6e-48: 182: 30.53