Protein: GLYR1
Cytokine-like nuclear factor N-PAC (NPAC) (3-hydroxyisobutyrate dehydrogenase-like protein) (Glyoxylate reductase 1 homolog) (Nuclear protein NP60) (Nuclear protein of 60 kDa) (Nucleosome-destabilizing factor) (hNDF) (Putative oxidoreductase GLYR1)

Gene: GLYR1
Organism: Homo sapiens
Interactions: 244
UniProt ID: Q49A26

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

998382

H31
Histone H3.1

5

19

Small-scale

0.909

High

1193396

H2AW
Core histone macro-H2A.2

2

11

High-throughput

0.811

High

447080

NPM
Nucleophosmin

4

2

High-throughput

0.699

High

1162946

H2B2E
Histone H2B type 2-E

1

14

High-throughput

0.691

High

1122987

FHL2
Four and a half LIM domains protein 2

4

0

High-throughput

0.668

High

1193347

KDM1B
Lysine-specific histone demethylase 2

3

2

High-throughput

0.667

High

1193379

NSD3
Histone-lysine N-methyltransferase NSD3

1

7

High-throughput

0.656

High

372186

MYC
Myc proto-oncogene protein

3

8

High-throughput

0.640

High

1161471

IF16
Gamma-interferon-inducible protein 16

3

4

High-throughput

0.640

High

986062

RL8
Large ribosomal subunit protein uL2

3

0

High-throughput

0.638

High

521721

H14
Histone H1.4

2

7

High-throughput

0.628

High

977016

CNBP
CCHC-type zinc finger nucleic acid binding protein

2

1

High-throughput

0.628

High

1193335

ZCCHV
Zinc finger CCCH-type antiviral protein 1

2

14

High-throughput

0.628

High

1193350

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

2

4

High-throughput

0.628

High

1193353

DGCR8
Microprocessor complex subunit DGCR8

2

1

High-throughput

0.628

High

1193390

PRDM5
PR domain zinc finger protein 5

2

1

High-throughput

0.628

High

419016

H2A1B
Histone H2A type 1-B/E

1

4

High-throughput

0.618

High

883558

CENPA
Histone H3-like centromeric protein A

1

19

High-throughput

0.618

High

980809

H2B1C
Histone H2B type 1-C/E/F/G/I

1

14

High-throughput

0.618

High

1016907

H33
Histone H3.3

1

19

High-throughput

0.618

High

182310

WDR46
WD repeat-containing protein 46

2

7

High-throughput

0.611

High

568149

PLSL
Plastin-2

2

3

High-throughput

0.611

High

902845

BLK
Tyrosine-protein kinase Blk

2

1

High-throughput

0.611

High

978975

RS6
Small ribosomal subunit protein eS6

2

2

High-throughput

0.611

High

1089426

ILF2
Interleukin enhancer-binding factor 2

2

1

High-throughput

0.611

High

848140

MAGA1
Melanoma-associated antigen 1

3

2

High-throughput

0.609

High

937474

CDN2D
Cyclin-dependent kinase 4 inhibitor D

2

4

High-throughput

0.606

High

208272

RRP8
Ribosomal RNA-processing protein 8

2

0

High-throughput

0.602

High

859848

RL28
Large ribosomal subunit protein eL28

2

0

High-throughput

0.602

High

961744

RL37A
Large ribosomal subunit protein eL43

2

0

High-throughput

0.602

High

984425

RL30
Large ribosomal subunit protein eL30

2

0

High-throughput

0.602

High

1037513

RL18A
Large ribosomal subunit protein eL20

2

0

High-throughput

0.602

High

1193373

ZNF2
Zinc finger protein 2

2

0

High-throughput

0.602

High

1193395

NOP53
Ribosome biogenesis protein NOP53

2

0

High-throughput

0.602

High

1193346

EIF1A
Probable RNA-binding protein EIF1AD

2

0

High-throughput

0.601

High

288661

NPM3
Nucleoplasmin-3

2

4

High-throughput

0.601

High

1037181

H11
Histone H1.1

2

7

High-throughput

0.601

High

1193384

LN28A
Protein lin-28 homolog A

2

2

High-throughput

0.601

High

396240

ESR1
Estrogen receptor

2

6

High-throughput

0.594

High

881710

FNTB
Protein farnesyltransferase subunit beta

2

0

High-throughput

0.585

High

1193365

CPNS2
Calpain small subunit 2

2

0

High-throughput

0.585

High

1193378

LOXE3
Hydroperoxide isomerase ALOXE3

2

0

High-throughput

0.585

High

1193376

NTM1A
N-terminal Xaa-Pro-Lys N-methyltransferase 1

2

0

High-throughput

0.580

High

290584

SURF6
Surfeit locus protein 6

2

0

High-throughput

0.576

High

1193403

ZN346
Zinc finger protein 346

2

0

High-throughput

0.576

High

1193344

SH2D3
SH2 domain-containing protein 3C

2

4

High-throughput

0.571

High

348863

CLIC3
Chloride intracellular channel protein 3

2

2

High-throughput

0.553

High

1071158

ARL16
ADP-ribosylation factor-like protein 16

2

1

High-throughput

0.553

High

191662

MAGB2
Melanoma-associated antigen B2

2

2

High-throughput

0.549

High

666840

CCNC
Cyclin-C

1

0

High-throughput

0.549

High

140946

NOP56
Nucleolar protein 56

1

1

High-throughput

0.536

High

287008

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

11

High-throughput

0.536

High

301077

RL1D1
Ribosomal L1 domain-containing protein 1

1

2

High-throughput

0.536

High

345900

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

11

High-throughput

0.536

High

428792

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.536

High

595451

H15
Histone H1.5

1

7

High-throughput

0.536

High

595791

H13
Histone H1.3

1

7

High-throughput

0.536

High

596132

H12
Histone H1.2

1

7

High-throughput

0.536

High

615811

RL17
Large ribosomal subunit protein uL22

1

1

High-throughput

0.536

High

686192

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.536

High

785202

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.536

High

809657

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.536

High

824172

RL13A
Large ribosomal subunit protein uL13

1

1

High-throughput

0.536

High

833120

MNDA
Myeloid cell nuclear differentiation antigen

1

4

High-throughput

0.536

High

841376

RBM34
RNA-binding protein 34

1

1

High-throughput

0.536

High

842394

RL35
Large ribosomal subunit protein uL29

1

1

High-throughput

0.536

High

855101

NOP2
28S rRNA

1

3

High-throughput

0.536

High

868355

CDX1
Homeobox protein CDX-1

1

4

High-throughput

0.536

High

985192

RL10A
Large ribosomal subunit protein uL1

1

2

High-throughput

0.536

High

1006437

SRPK2
SRSF protein kinase 2

1

5

High-throughput

0.536

High

1008754

RED1
Double-stranded RNA-specific editase 1

1

6

High-throughput

0.536

High

1016034

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.536

High

1016460

SRSF3
Serine/arginine-rich splicing factor 3

1

13

High-throughput

0.536

High

1027496

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

5

High-throughput

0.536

High

1061005

SRSF1
Serine/arginine-rich splicing factor 1

1

11

High-throughput

0.536

High

1062005

SRSF4
Serine/arginine-rich splicing factor 4

1

8

High-throughput

0.536

High

1089692

ILF3
Interleukin enhancer-binding factor 3

1

7

High-throughput

0.536

High

1097679

STK3
Serine/threonine-protein kinase 3

1

4

High-throughput

0.536

High

1099100

SRSF5
Serine/arginine-rich splicing factor 5

1

10

High-throughput

0.536

High

1099375

SRSF6
Serine/arginine-rich splicing factor 6

1

11

High-throughput

0.536

High

1134604

NUMA1
Nuclear mitotic apparatus protein 1

1

3

High-throughput

0.536

High

1159954

SRSF7
Serine/arginine-rich splicing factor 7

1

9

High-throughput

0.536

High

1193354

LAR4B
La-related protein 4B

1

1

High-throughput

0.536

High

1193369

RBM4B
RNA-binding protein 4B

1

2

High-throughput

0.536

High

1193370

MBB1A
Myb-binding protein 1A

1

1

High-throughput

0.536

High

1193377

RBM4
RNA-binding protein 4

1

2

High-throughput

0.536

High

1193391

DDX21
Nucleolar RNA helicase 2

1

4

High-throughput

0.536

High

1193394

LYAR
Cell growth-regulating nucleolar protein

1

2

High-throughput

0.536

High

1193399

ZBT47
Zinc finger and BTB domain-containing protein 47

1

1

High-throughput

0.536

High

1193405

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

1193404

HECD1
E3 ubiquitin-protein ligase HECTD1

2

7

High-throughput

0.533

High

1161892

H31T
Histone H3.1t

1

19

High-throughput

0.527

High

899941

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.518

High

280645

PR40A
Pre-mRNA-processing factor 40 homolog A

1

5

High-throughput

0.515

High

937015

CASP6
Caspase-6

1

3

High-throughput

0.515

High

981517

RAN
GTP-binding nuclear protein Ran

1

2

High-throughput

0.515

High

1193359

OPTN
Optineurin

1

8

High-throughput

0.515

High

1193406

UBQL1
Ubiquilin-1

1

1

High-throughput

0.515

High

137452

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

0

High-throughput

0.513

High

476704

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.513

High

586726

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.513

High

788669

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

860219

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

860771

RS10
Small ribosomal subunit protein eS10

1

0

High-throughput

0.513

High

898676

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.513

High

959808

RS3A
Small ribosomal subunit protein eS1

1

0

High-throughput

0.513

High

969893

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

975721

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

978552

RL23A
Large ribosomal subunit protein uL23

1

0

High-throughput

0.513

High

984791

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.513

High

985690

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

1013066

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

1112040

KRR1
KRR1 small subunit processome component homolog

1

0

High-throughput

0.513

High

1126419

CAPR1
Caprin-1

1

0

High-throughput

0.513

High

1139926

RRS1
Ribosome biogenesis regulatory protein homolog

1

0

High-throughput

0.513

High

1193341

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.513

High

1193360

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

1193387

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

1193393

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.513

High

1193409

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

246636

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.508

High

130966

HIP1
Huntingtin-interacting protein 1

1

0

High-throughput

0.493

High

517770

GLI4
Zinc finger protein GLI4

1

1

High-throughput

0.489

High

658824

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

1

High-throughput

0.489

High

1159376

ECM1
Extracellular matrix protein 1

1

1

High-throughput

0.489

High

1178041

RN151
RING finger protein 151

1

2

High-throughput

0.489

High

1193338

PNM8A
Paraneoplastic antigen-like protein 8A

1

1

High-throughput

0.489

High

1193407

SRPK3
SRSF protein kinase 3

1

6

High-throughput

0.489

High

96692

E9PAV9
G patch domain-containing protein 4

1

1

High-throughput

0.479

High

129142

MEN1
Menin

1

1

High-throughput

0.479

High

157450

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.479

High

218256

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

223097

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

225017

TLX3
T-cell leukemia homeobox protein 3

1

3

High-throughput

0.479

High

227581

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

248306

HBP1
HMG box-containing protein 1

1

5

High-throughput

0.479

High

254376

CC14B
Dual specificity protein phosphatase CDC14B

1

5

High-throughput

0.479

High

272233

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.479

High

285318

EED
Polycomb protein EED

1

9

High-throughput

0.479

High

319810

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

342901

HERC2
E3 ubiquitin-protein ligase HERC2

1

5

High-throughput

0.479

High

349109

LATS1
Serine/threonine-protein kinase LATS1

1

1

High-throughput

0.479

High

400927

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

406240

MYCN
N-myc proto-oncogene protein

1

8

High-throughput

0.479

High

487381

PARP1
Poly [ADP-ribose] polymerase 1

1

15

High-throughput

0.479

High

504902

H2AB2
Histone H2A-Bbd type 2/3

1

5

High-throughput

0.479

High

558180

XRCC6
X-ray repair cross-complementing protein 6

1

6

High-throughput

0.479

High

685212

PAX6
Paired box protein Pax-6

1

1

High-throughput

0.479

High

695612

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

697134

APEX1
DNA repair nuclease/redox regulator APEX1

1

4

High-throughput

0.479

High

768340

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

851582

GATA4
Transcription factor GATA-4

1

2

High-throughput

0.479

High

872387

SOX2
Transcription factor SOX-2

1

8

High-throughput

0.479

High

904796

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

937268

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

11

High-throughput

0.479

High

945706

FOXL2
Forkhead box protein L2

1

6

High-throughput

0.479

High

970605

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

979756

H4
Histone H4

1

4

High-throughput

0.479

High

1088378

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

10

High-throughput

0.479

High

1106929

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

1132737

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

10

High-throughput

0.479

High

1137740

TNIP1
TNFAIP3-interacting protein 1

1

7

High-throughput

0.479

High

1140364

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1193327

HABP4
Intracellular hyaluronan-binding protein 4

1

4

High-throughput

0.479

High

1193340

CUL9
Cullin-9

1

3

High-throughput

0.479

High

1193343

FBXW8
F-box/WD repeat-containing protein 8

1

7

High-throughput

0.479

High

1193345

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

2

High-throughput

0.479

High

1193348

SERB1
SERPINE1 mRNA-binding protein 1

1

4

High-throughput

0.479

High

1193349

NUP43
Nucleoporin Nup43

1

14

High-throughput

0.479

High

1193351

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1193352

DNJC9
DnaJ homolog subfamily C member 9

1

5

High-throughput

0.479

High

1193355

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1193356

KAT6A
Histone acetyltransferase KAT6A

1

12

High-throughput

0.479

High

1193357

FBXW7
F-box/WD repeat-containing protein 7

1

6

High-throughput

0.479

High

1193367

RING2
E3 ubiquitin-protein ligase RING2

1

6

High-throughput

0.479

High

1193368

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.479

High

1193381

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

1193386

RC3H2
Roquin-2

1

3

High-throughput

0.479

High

1193389

ANLN
Anillin

1

3

High-throughput

0.479

High

1193392

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

1193398

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

3

High-throughput

0.479

High

1193400

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1193408

ZN330
Zinc finger protein 330

1

2

High-throughput

0.479

High

1193410

TRRAP
Transformation/transcription domain-associated protein

1

4

High-throughput

0.479

High

1193411

MAFB
Transcription factor MafB

1

2

High-throughput

0.479

High

650199

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.470

High

944487

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.460

High

810137

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

832531

ETV3
ETS translocation variant 3

1

0

High-throughput

0.458

High

839561

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.458

High

895725

LHX2
LIM/homeobox protein Lhx2

1

0

High-throughput

0.458

High

960131

RL26
Large ribosomal subunit protein uL24

1

0

High-throughput

0.458

High

1137330

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1161008

FSCN1
Fascin

1

0

High-throughput

0.458

High

1193358

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

1193382

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

955242

CDC42
Cell division control protein 42 homolog

1

4

Small-scale

0.457

High

374645

RASH
GTPase HRas

1

2

High-throughput

0.445

High

529910

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.445

High

601706

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.445

High

934695

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.445

High

967452

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.445

High

994574

YBOX1
Y-box-binding protein 1

1

1

High-throughput

0.445

High

1136785

MO4L2
Mortality factor 4-like protein 2

1

1

High-throughput

0.445

High

1193332

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.445

High

171888

ZN263
Zinc finger protein 263

1

2

Small-scale

0.437

High

551620

NFH
Neurofilament heavy polypeptide

1

1

High-throughput

0.437

High

1024610

VIGLN
Vigilin

1

1

High-throughput

0.437

High

1193330

RC3H1
Roquin-1

1

1

High-throughput

0.437

High

1193333

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

1193336

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

1193362

DDRGK
DDRGK domain-containing protein 1

1

2

High-throughput

0.437

High

1193383

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

1193397

RN181
E3 ubiquitin-protein ligase RNF181

1

2

High-throughput

0.437

High

442737

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.426

High

1193371

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.426

High

1193380

REXO4
RNA exonuclease 4

1

0

High-throughput

0.426

High

1193385

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.426

High

72781

B0UZZ8
WD repeat-containing protein 46

1

7

High-throughput

0.407

High

1193328

GPTC4
G patch domain-containing protein 4

1

1

High-throughput

0.407

High

1193375

ZSA5A
Zinc finger and SCAN domain-containing protein 5A

1

3

High-throughput

0.407

High

1193339

SPA12
Serpin A12

3

0

High-throughput

0.347

High

1193361

PRR11
Proline-rich protein 11

3

0

High-throughput

0.347

High

1193388

SSF1
Suppressor of SWI4 1 homolog

2

0

High-throughput

0.328

High

1193342

CF206
Cilia- and flagella-associated protein 206

1

0

High-throughput

0.299

High

376395

PDGFB
Platelet-derived growth factor subunit B

1

0

High-throughput

0.279

Low

935406

FGF8
Fibroblast growth factor 8

1

0

High-throughput

0.279

Low

1127393

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1168509

KNOP1
Lysine-rich nucleolar protein 1

1

0

High-throughput

0.279

Low

1193326

PKHO1
Pleckstrin homology domain-containing family O member 1

1

0

High-throughput

0.279

Low

1193331

RSBN1
Lysine-specific demethylase 9

1

0

High-throughput

0.279

Low

1193363

ZN668
Zinc finger protein 668

1

0

High-throughput

0.279

Low

1193364

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.279

Low

1193366

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

1193372

UTP23
rRNA-processing protein UTP23 homolog

1

0

High-throughput

0.279

Low

1193401

IL17B
Interleukin-17B

1

0

High-throughput

0.279

Low

1193402

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.279

Low

562087

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.268

Low

1133871

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.268

Low

293778

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1193334

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

1193329

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low

1193337

SZRD1
SUZ RNA-binding domain-containing

1

0

High-throughput

0.232

Low

1193374

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025