Interactor 1: SCN5A (Q14524)
Sodium channel protein type 5 subunit alpha (Sodium channel protein cardiac muscle subunit alpha) (Sodium channel protein type V subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.5) (hH1)
Gene: SCN5A

Interactor 2: NED4L (Q96PU5)
E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2)
Gene: NEDD4L

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 31900993, 28296171
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0044325 - transmembrane transporter binding
GO:0086005 - ventricular cardiac muscle cell action potential
GO:1902305 - regulation of sodium ion transmembrane transport
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2016
Hs

1 975
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024