HitPredict

Interactor 1: K1H2 (Q14532)
Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2) (Keratin-32) (K32)
Gene: KRT32

Interactor 2: AINX (Q16352)
Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66) (Neurofilament 5)
Gene: INA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005882 - intermediate filament GO:0045109 - intermediate filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 448 Hs			1 499
+	Hs
		359360 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		AINX_HUMAN (1-499): 1.25e-175: 504: 100.00
+	Hs
		359292 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		NFM_HUMAN (9-480): 1.71e-96: 313: 47.43
+	Hs
		359291 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		NFL_HUMAN (70-408): 3.34e-97: 305: 58.11
+	Hs
		422138 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		NFL_HUMAN (70-408): 3.34e-97: 305: 58.11
+	Hs
		359310 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		PERI_HUMAN (11-430): 6.23e-88: 279: 50.12
+	Hs
		531443 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		DESM_HUMAN (57-418): 4.71e-85: 271: 51.38
+	Hs
		359348 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		KRT81_HUMAN (5-415): 6.99e-81: 262: 29.93
+	Hs
		359330 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		KRT85_HUMAN (5-415): 4.25e-80: 260: 31.16
+	Hs
		213924 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		KRT86_HUMAN (5-415): 1.75e-79: 257: 30.17
+	Hs
		531442 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		GFAP_HUMAN (62-417): 1.16e-82: 264: 49.44
+	Hs
		318773 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C75_HUMAN (2-410): 2.98e-71: 238: 30.92
+	Hs
		359368 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C79_HUMAN (10-418): 7.42e-69: 231: 29.02
+	Hs
		359351 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C72_HUMAN (10-410): 1.71e-64: 219: 29.53
+	Hs
		359299 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C5_HUMAN (59-410): 8.69e-59: 205: 31.07
+	Hs
		359315 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C6C_HUMAN (59-410): 7.2e-59: 205: 30.51
+	Hs
		380441 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C6B_HUMAN (59-410): 7.35e-59: 205: 30.23
+	Hs
		531441 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C5_HUMAN (59-410): 8.69e-59: 205: 31.07
+	Hs
		531456 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C6C_HUMAN (59-410): 7.2e-59: 205: 30.51
+	Hs
		359460 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C6A_HUMAN (59-410): 3.18e-57: 201: 30.51
+	Mm
		1322195 K1C17_MOUSE (41-423): 2.06e-143: 418: 50.13		K2C7_MOUSE (13-408): 5.33e-54: 189: 33.75