Protein: LSB3
LAS seventeen-binding protein 3 (LAS17-binding protein 3)

Gene: LSB3
Organism: Saccharomyces cerevisiae S288C
Interactions: 193
UniProt ID: P43603

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005935 - cellular bud neck
GO:0030479 - actin cortical patch
GO:0035091 - phosphatidylinositol binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

744879

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

8

20

Small-scale

0.972

High

850435

LSB3
LAS seventeen-binding protein 3

4

18

High-throughput

0.896

High

745016

YSC84
Protein YSC84

3

19

High-throughput

0.857

High

587319

ABP1
Actin-binding protein

2

20

High-throughput

0.817

High

806251

RGD3
Rho-GTPase-activating protein RGD3

2

1

High-throughput

0.778

High

850511

LAS17
Proline-rich protein LAS17

8

20

Small-scale

0.758

High

850495

CUE5
Ubiquitin-binding protein CUE5

7

2

High-throughput

0.752

High

850487

BSP1
F-actin capping regulator BSP1

5

2

Small-scale

0.725

High

850459

APP1
Phosphatidate phosphatase APP1

4

2

High-throughput

0.707

High

822390

HUA1
Proline-rich protein HUA1

4

2

High-throughput

0.702

High

739295

ECM25
Protein ECM25

1

1

High-throughput

0.698

High

850477

MYO5
Myosin-5

1

17

High-throughput

0.698

High

829753

GTS1
Protein GTS1

4

18

High-throughput

0.694

High

665832

KPC1
Protein kinase C-like 1

1

11

High-throughput

0.691

High

850476

GYL1
Probable GTPase-activating protein GYL1

3

7

High-throughput

0.683

High

850501

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

3

3

High-throughput

0.683

High

814221

RV167
Reduced viability upon starvation protein 167

1

20

High-throughput

0.665

High

850516

CMR1
DNA damage-binding protein CMR1

3

8

High-throughput

0.651

High

850458

INN1
Ingression protein 1

1

4

High-throughput

0.647

High

850479

AVO2
Target of rapamycin complex 2 subunit AVO2

1

17

High-throughput

0.647

High

850513

TCB1
Tricalbin-1

1

1

High-throughput

0.647

High

746168

SEC8
Exocyst complex component SEC8

2

2

High-throughput

0.633

High

850510

GYP5
GTPase-activating protein GYP5

2

7

High-throughput

0.633

High

722039

XPO1
Exportin-1

2

3

High-throughput

0.633

High

678112

SYP1
Suppressor of yeast profilin deletion

2

8

High-throughput

0.632

High

545317

SSB1
Ribosome-associated molecular chaperone SSB1

3

15

High-throughput

0.624

High

479268

CDC6
Cell division control protein 6

2

2

High-throughput

0.619

High

824684

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

9

High-throughput

0.619

High

850449

ROG1
Putative lipase ROG1

2

1

High-throughput

0.619

High

850451

YBP2
YAP1-binding protein 2

2

2

High-throughput

0.619

High

850441

ACF4
Assembly-complementing factor 4

3

2

High-throughput

0.619

High

794144

ERT1
Transcription activator of gluconeogenesis ERT1

2

2

High-throughput

0.619

High

797152

AIM3
Altered inheritance of mitochondria protein 3

2

20

High-throughput

0.619

High

850469

SKY1
Serine/threonine-protein kinase SKY1

2

17

High-throughput

0.619

High

850509

LDB17
Protein LDB17

2

9

Small-scale

0.613

High

850453

AP18B
Clathrin coat assembly protein AP180B

2

10

High-throughput

0.608

High

752006

PACC
pH-response transcription factor pacC/RIM101

2

8

High-throughput

0.602

High

826424

AIM21
Altered inheritance of mitochondria protein 21

2

4

High-throughput

0.602

High

850461

SLM2
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2

2

1

High-throughput

0.602

High

579607

HSC82
ATP-dependent molecular chaperone HSC82

2

9

High-throughput

0.584

High

677759

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

2

5

High-throughput

0.578

High

524328

HSP71
Heat shock protein SSA1

2

13

High-throughput

0.571

High

793378

AGP2
General amino acid permease AGP2

2

3

High-throughput

0.550

High

598883

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

2

High-throughput

0.541

High

726157

2AAA
Protein phosphatase PP2A regulatory subunit A

1

2

High-throughput

0.541

High

744389

ATC5
Phospholipid-transporting ATPase DNF1

1

1

High-throughput

0.541

High

747132

RT04
Small ribosomal subunit protein uS2m

1

2

High-throughput

0.541

High

755121

GCN1
eIF-2-alpha kinase activator GCN1

1

2

High-throughput

0.541

High

794046

KTR3
Probable mannosyltransferase KTR3

1

1

High-throughput

0.541

High

849908

WWM1
WW domain-containing protein WWM1

1

1

High-throughput

0.541

High

850445

INP52
Polyphosphatidylinositol phosphatase INP52

1

20

High-throughput

0.541

High

850447

MCM6
DNA replication licensing factor MCM6

1

4

High-throughput

0.541

High

850450

VPS73
Vacuolar protein sorting-associated protein 73

1

1

High-throughput

0.541

High

850454

SSK2
MAP kinase kinase kinase SSK2

1

11

High-throughput

0.541

High

850460

AQR1
Probable transporter AQR1

1

1

High-throughput

0.541

High

850467

MET31
Transcriptional regulator MET31

1

5

High-throughput

0.541

High

850480

YM87
Uncharacterized membrane protein YMR253C

1

2

High-throughput

0.541

High

850488

SYG2
Glycine--tRNA ligase 2

1

7

High-throughput

0.541

High

850497

SRL1
Cell wall protein SRL1

1

1

High-throughput

0.541

High

850499

HUA2
Protein HUA2

1

2

High-throughput

0.541

High

850508

INP53
Polyphosphatidylinositol phosphatase INP53

1

20

High-throughput

0.541

High

751861

SLA2
Protein SLA2

1

20

High-throughput

0.536

High

807770

CSK2C
Casein kinase II subunit beta'

1

1

High-throughput

0.536

High

850439

SDHX
Succinate dehydrogenase [ubiquinone] flavoprotein subunit 2, mitochondrial

1

1

High-throughput

0.536

High

850444

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

9

High-throughput

0.536

High

850462

ARK1
Actin-regulating kinase 1

1

8

High-throughput

0.536

High

850486

DCK1
DOCK-like protein 1

1

8

High-throughput

0.536

High

850483

FUS2
Nuclear fusion protein FUS2

1

0

High-throughput

0.518

High

850490

LEC1
PX domain-containing protein LEC1

1

0

High-throughput

0.518

High

850491

MRX9
MIOREX complex component 9

1

0

High-throughput

0.518

High

850498

VPS54
Vacuolar protein sorting-associated protein 54

1

0

High-throughput

0.518

High

471414

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.513

High

746041

YME2
Mitochondrial escape protein 2

1

0

High-throughput

0.513

High

518060

SSBP1
Single-stranded nucleic acid-binding protein

1

3

High-throughput

0.501

High

522553

MRS3
Mitochondrial RNA-splicing protein MRS3

1

6

High-throughput

0.501

High

602530

PHO85
Cyclin-dependent protein kinase PHO85

1

4

High-throughput

0.501

High

656515

KC11
Casein kinase I homolog 1

1

12

High-throughput

0.501

High

725924

PSK1
Serine/threonine-protein kinase PSK1

1

10

High-throughput

0.501

High

784386

RM36
Large ribosomal subunit protein bL31m

1

1

High-throughput

0.501

High

793167

AKL1
Serine/threonine-protein kinase AKL1

1

9

High-throughput

0.501

High

797492

EXO5
Exonuclease V, mitochondrial

1

2

High-throughput

0.501

High

801857

KSP1
Serine/threonine-protein kinase KSP1

1

10

High-throughput

0.501

High

825405

PRK1
Actin-regulating kinase PRK1

1

11

High-throughput

0.501

High

829820

MVP1
Sorting nexin MVP1

1

15

High-throughput

0.501

High

836286

BNI1
Protein BNI1

1

7

High-throughput

0.501

High

850442

RT07
Small ribosomal subunit protein uS7m

1

1

High-throughput

0.501

High

850448

ATG1
Serine/threonine-protein kinase ATG1

1

11

High-throughput

0.501

High

850471

ENT5
Epsin-5

1

8

Small-scale

0.501

High

850481

SML1
Ribonucleotide reductase inhibitor protein SML1

1

1

High-throughput

0.501

High

850493

SHS1
Seventh homolog of septin 1

1

2

High-throughput

0.501

High

850503

TIP41
Type 2A phosphatase activator TIP41

1

1

High-throughput

0.501

High

571842

SNA3
Protein SNA3

1

1

High-throughput

0.494

High

673193

RRP7
Ribosomal RNA-processing protein 7

1

1

High-throughput

0.494

High

751189

CSE1
Importin alpha re-exporter

1

3

High-throughput

0.494

High

781829

GMH1
Protein GMH1

1

1

High-throughput

0.494

High

793245

BAP2
Leu/Val/Ile amino-acid permease

1

3

High-throughput

0.494

High

793271

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

1

3

High-throughput

0.494

High

796772

MMS4
Crossover junction endonuclease MMS4

1

1

High-throughput

0.494

High

802135

STB5
Protein STB5

1

1

High-throughput

0.494

High

835077

SYS1
Protein SYS1

1

1

High-throughput

0.494

High

850410

ATG18
Autophagy-related protein 18

1

4

High-throughput

0.494

High

850436

SA155
SIT4-associating protein SAP155

1

5

High-throughput

0.494

High

850443

ALG10
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

1

High-throughput

0.494

High

850457

TDA7
Topoisomerase I damage affected protein 7

1

20

High-throughput

0.494

High

850472

TVP15
Golgi apparatus membrane protein TVP15

1

1

High-throughput

0.494

High

850484

ENT2
Epsin-2

1

14

High-throughput

0.494

High

850507

RBD2
Rhomboid-type serine protease 2

1

4

High-throughput

0.494

High

850517

ATC8
Probable phospholipid-transporting ATPase DNF3

1

4

High-throughput

0.494

High

850468

THADA
tRNA

1

0

High-throughput

0.493

High

511103

YRF15
Y' element ATP-dependent helicase protein 1 copy 5

1

5

High-throughput

0.481

High

744082

PMD1
Negative regulator of sporulation PMD1

1

0

High-throughput

0.480

High

746334

RGT1
Glucose transport transcription regulator RGT1

1

0

High-throughput

0.480

High

827010

YAP5
AP-1-like transcription factor YAP5

1

0

High-throughput

0.480

High

850482

FMP42
Protein FMP42

1

0

High-throughput

0.480

High

392928

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.479

High

394673

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.479

High

416255

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

5

High-throughput

0.479

High

444557

DED1
ATP-dependent RNA helicase DED1

1

5

High-throughput

0.479

High

454671

ERG12
Mevalonate kinase

1

1

High-throughput

0.479

High

558776

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.479

High

581876

SYKC
Lysine--tRNA ligase, cytoplasmic

1

6

High-throughput

0.479

High

679814

CDC48
Cell division control protein 48

1

6

High-throughput

0.479

High

694574

SPT5
Transcription elongation factor SPT5

1

3

High-throughput

0.479

High

727127

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

747917

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

785936

LONM
Lon protease homolog, mitochondrial

1

7

High-throughput

0.479

High

793333

SYG
Glycine--tRNA ligase 1, mitochondrial

1

7

High-throughput

0.479

High

795419

ATG8
Autophagy-related protein 8

1

8

High-throughput

0.479

High

802565

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.479

High

802646

YHI0
Putative proline--tRNA ligase YHR020W

1

3

High-throughput

0.479

High

829872

SAS2
Histone acetyltransferase SAS2

1

2

Small-scale

0.479

High

850059

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

17

High-throughput

0.479

High

850455

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

3

High-throughput

0.479

High

850464

NUM1
Nuclear migration protein NUM1

1

20

High-throughput

0.479

High

850502

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

850475

RAD33
DNA repair protein RAD33

1

1

High-throughput

0.470

High

850466

NU100
Nucleoporin NUP100/NSP100

1

1

High-throughput

0.464

High

672906

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

850456

PDR16
Phosphatidylinositol transfer protein PDR16

1

0

High-throughput

0.458

High

850473

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

850496

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

454342

PHO2
Regulatory protein PHO2

1

5

High-throughput

0.457

High

678917

YCX7
Putative uncharacterized protein YCR087W

1

1

High-throughput

0.457

High

779930

YRA2
RNA annealing protein YRA2

1

1

High-throughput

0.457

High

781716

SA190
SIT4-associating protein SAP190

1

5

High-throughput

0.457

High

803191

WSC4
Cell wall integrity and stress response component 4

1

20

High-throughput

0.457

High

830056

CDC1
Cell division control protein 1

1

1

High-throughput

0.457

High

850438

ZAP1
Zinc-responsive transcriptional regulator ZAP1

1

3

High-throughput

0.457

High

850452

SCW11
Probable family 17 glucosidase SCW11

1

15

High-throughput

0.457

High

850465

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

1

7

High-throughput

0.457

High

850489

NVJ2
Nucleus-vacuole junction protein 2

1

2

High-throughput

0.457

High

850500

POM33
Pore membrane protein of 33 kDa

1

3

High-throughput

0.457

High

850504

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

1

High-throughput

0.457

High

850505

PUS1
tRNA pseudouridine synthase 1

1

1

High-throughput

0.457

High

806086

AP18A
Clathrin coat assembly protein AP180A

1

10

High-throughput

0.457

High

358259

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.445

High

453656

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

481664

HSP73
Heat shock protein SSA3

1

13

High-throughput

0.445

High

526997

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

592330

VATB
V-type proton ATPase subunit B

1

5

High-throughput

0.445

High

819076

SSB2
Ribosome-associated molecular chaperone SSB2

1

15

High-throughput

0.445

High

850446

EXG2
Glucan 1,3-beta-glucosidase 2

1

1

High-throughput

0.439

High

682320

SPB4
ATP-dependent rRNA helicase SPB4

1

9

High-throughput

0.437

High

707435

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

736389

MET4
Transcriptional activator of sulfur metabolism MET4

1

1

High-throughput

0.437

High

812421

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

850474

RUVB1
RuvB-like protein 1

1

5

High-throughput

0.437

High

850494

ENB1
Siderophore iron transporter ENB1

1

1

High-throughput

0.437

High

850512

RUVB2
RuvB-like protein 2

1

5

High-throughput

0.437

High

572612

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.426

High

554016

TCPA
T-complex protein 1 subunit alpha

1

4

High-throughput

0.407

High

585968

CSK21
Casein kinase II subunit alpha

1

9

High-throughput

0.407

High

622973

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.407

High

592779

ERD1
Protein ERD1

1

0

High-throughput

0.282

High

673641

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.282

High

850437

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.282

High

850492

YET3
Endoplasmic reticulum transmembrane protein 3

1

0

High-throughput

0.282

High

850506

TM115
Transmembrane protein 115 homolog

1

0

High-throughput

0.282

High

850514

YD012
Lipid-anchored protein YDL012C

1

0

High-throughput

0.282

High

674418

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.261

Low

812967

YAN8
Uncharacterized protein YAR068W

1

0

High-throughput

0.261

Low

818595

YEY8
Uncharacterized protein YER158C

1

0

High-throughput

0.261

Low

808844

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

826018

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.249

Low

826598

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

849638

EMP47
Protein EMP47

1

0

High-throughput

0.249

Low

850440

NU192
Nucleoporin NUP192

1

0

High-throughput

0.249

Low

850470

YMC0
Uncharacterized protein YML020W

1

0

High-throughput

0.249

Low

850478

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

850485

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

850515

RKM4
Ribosomal lysine N-methyltransferase 4

1

0

High-throughput

0.249

Low

850463

YD271
Putative uncharacterized protein YDR271C

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025