HitPredict

Interactor 1: K1H2 (Q14532)
Keratin, type I cuticular Ha2 (Hair keratin, type I Ha2) (Keratin-32) (K32)
Gene: KRT32

Interactor 2: K2C78 (Q8N1N4)
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)
Gene: KRT78

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	36949045
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	GO:0005829 - cytosol GO:0045109 - intermediate filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 448 Hs			1 520
+	Hs
		359378 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C1B_HUMAN (66-435): 6.29e-126: 381: 56.49
+	Hs
		359290 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09
+	Hs
		408990 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09
+	Hs
		359288 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C1_HUMAN (76-442): 7.29e-112: 347: 56.95
+	Hs
		380549 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C1_HUMAN (76-442): 7.29e-112: 347: 56.95
+	Hs
		359348 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		KRT81_HUMAN (1-502): 8.51e-104: 322: 39.69
+	Hs
		213924 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		KRT86_HUMAN (1-499): 1.62e-103: 321: 39.88
+	Hs
		359330 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		KRT85_HUMAN (3-489): 6.87e-95: 299: 40.77
+	Hs
		318773 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C75_HUMAN (2-516): 7.92e-95: 300: 48.22
+	Hs
		359368 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C79_HUMAN (9-442): 1.75e-88: 283: 53.14
+	Hs
		359351 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C72_HUMAN (1-502): 4.44e-85: 274: 47.85
+	Hs
		359315 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C6C_HUMAN (76-448): 1.24e-79: 261: 59.52
+	Hs
		359381 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C78_HUMAN (1-520): 1.25e-79: 259: 100.00
+	Hs
		359299 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C5_HUMAN (76-427): 3.19e-78: 258: 62.50
+	Hs
		380441 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C6B_HUMAN (76-448): 4.72e-80: 262: 59.25
+	Hs
		359460 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C6A_HUMAN (76-448): 1.02e-78: 258: 59.79
+	Hs
		531441 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C5_HUMAN (76-427): 3.19e-78: 258: 62.50
+	Mm
		1322195 K1C17_MOUSE (41-423): 2.06e-143: 418: 50.13		K2C7_MOUSE (32-482): 1.27e-71: 237: 48.12
+	Hs
		359297 K1C14_HUMAN (94-407): 1.1e-141: 415: 59.87		K2C3_HUMAN (83-428): 5.14e-68: 232: 62.07
+	Hs
		517735 K1C13_HUMAN (85-419): 3.5e-139: 408: 55.06		K2C3_HUMAN (83-428): 5.14e-68: 232: 62.07