Protein: TPO1
Polyamine transporter 1

Gene: TPO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 75
UniProt ID: Q07824

Gene Ontology (top 5):
GO:0000296 - spermine transport
GO:0000297 - spermine transmembrane transporter activity
GO:0000329 - fungal-type vacuole membrane
GO:0005886 - plasma membrane
GO:0015297 - antiporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

720853

ITR1
Myo-inositol transporter 1

1

17

High-throughput

0.698

High

737256

HXT1
Low-affinity glucose transporter HXT1

1

17

High-throughput

0.698

High

802052

HXT5
Probable glucose transporter HXT5

1

17

High-throughput

0.698

High

825147

QDR2
Quinidine resistance protein 2

1

17

High-throughput

0.698

High

919325

TPO2
Polyamine transporter 2

1

16

High-throughput

0.698

High

1055192

TPO3
Polyamine transporter 3

1

17

High-throughput

0.698

High

1060321

TPO1
Polyamine transporter 1

1

17

High-throughput

0.698

High

751126

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

2

20

High-throughput

0.613

High

625928

HNM1
Choline transporter

1

18

High-throughput

0.541

High

663621

VATO
V-type proton ATPase subunit c''

1

6

High-throughput

0.541

High

676553

VATL1
V-type proton ATPase subunit c

1

6

High-throughput

0.541

High

740376

SNQ2
Protein SNQ2

1

20

High-throughput

0.541

High

746019

VATL2
V-type proton ATPase subunit c'

1

6

High-throughput

0.541

High

776749

SFK1
Protein SFK1

1

6

High-throughput

0.541

High

779886

MID2
Cell wall integrity sensor MID2

1

6

High-throughput

0.541

High

812954

PRM9
Pheromone-regulated membrane protein 9

1

15

High-throughput

0.541

High

812962

MST28
Multicopy suppressor of SEC21 protein 28

1

15

High-throughput

0.541

High

849743

FET5
Iron transport multicopper oxidase FET5

1

1

High-throughput

0.541

High

871012

TCB2
Tricalbin-2

1

9

High-throughput

0.541

High

894376

MUP1
High-affinity methionine permease

1

18

High-throughput

0.541

High

916784

ERG25
C-4 methylsterol oxidase ERG25

1

3

High-throughput

0.541

High

917997

MST27
Multicopy suppressor of SEC21 protein 27

1

15

High-throughput

0.541

High

920737

DIP5
Dicarboxylic amino acid permease

1

7

High-throughput

0.541

High

920746

MEP3
Ammonium transporter MEP3

1

3

High-throughput

0.541

High

1038598

PDR12
ATP-dependent permease PDR12

1

20

High-throughput

0.541

High

1043476

TCB3
Tricalbin-3

1

9

High-throughput

0.541

High

1043525

GAS3
Probable 1,3-beta-glucanosyltransferase GAS3

1

4

High-throughput

0.541

High

1056535

YL413
Cell membrane protein YLR413W

1

4

High-throughput

0.541

High

1059773

FMP45
SUR7 family protein FMP45

1

7

High-throughput

0.541

High

1060326

YB029
UPF0768 protein YBL029C-A

1

2

High-throughput

0.541

High

798746

PHO89
Phosphate permease PHO89

1

0

High-throughput

0.518

High

1052355

MSC3
Meiotic sister-chromatid recombination protein 3

1

0

High-throughput

0.518

High

1054065

YL326
Uncharacterized membrane protein YLR326W

1

0

High-throughput

0.518

High

1060327

CTPP3
Lipid-anchored plasma membrane protein CPP3

1

0

High-throughput

0.518

High

692441

KCC1
Calcium/calmodulin-dependent protein kinase I

1

2

High-throughput

0.501

High

560289

KEX2
Kexin

1

1

High-throughput

0.494

High

577229

SEC63
Protein translocation protein SEC63

1

3

High-throughput

0.494

High

598526

ALG1
Chitobiosyldiphosphodolichol beta-mannosyltransferase

1

1

High-throughput

0.494

High

672838

ELO2
Fatty acid elongase 2

1

9

High-throughput

0.494

High

735363

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

3

High-throughput

0.494

High

750211

UFD4
Ubiquitin fusion degradation protein 4

1

2

High-throughput

0.494

High

776394

YET1
Endoplasmic reticulum transmembrane protein 1

1

3

High-throughput

0.494

High

796287

RFS1
Protein RFS1

1

5

High-throughput

0.494

High

797068

PHO88
SRP-independent targeting protein 3

1

9

High-throughput

0.494

High

797459

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

6

High-throughput

0.494

High

805911

YHU0
UPF0641 membrane protein YHR140W

1

2

High-throughput

0.494

High

808699

SUR2
Sphingolipid C4-hydroxylase SUR2

1

3

High-throughput

0.494

High

822352

ELO3
Fatty acid elongase 3

1

9

High-throughput

0.494

High

826282

SNL1
HSP70 co-chaperone SNL1

1

1

High-throughput

0.494

High

1038530

SHR3
Secretory component protein SHR3

1

2

High-throughput

0.494

High

1038806

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

1

High-throughput

0.494

High

1046553

PLM2
Protein PLM2

1

5

High-throughput

0.494

High

1047505

GSF2
Glucose-signaling factor 2

1

8

High-throughput

0.494

High

1060323

ERP4
Protein ERP4

1

3

High-throughput

0.494

High

511081

COS3
Protein COS3

1

15

High-throughput

0.481

High

748911

SWE1
Mitosis inhibitor protein kinase SWE1

1

1

High-throughput

0.457

High

1060325

CMR1
DNA damage-binding protein CMR1

1

4

High-throughput

0.439

High

752072

DUR3
Urea active transporter

1

0

High-throughput

0.438

High

752802

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.437

High

826884

DSN1
Kinetochore-associated protein DSN1

1

7

High-throughput

0.437

High

1060324

PSF1
DNA replication complex GINS protein PSF1

1

1

High-throughput

0.417

High

726027

LDS1
Outer spore wall protein LDS1

1

0

High-throughput

0.282

High

754665

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

1

0

High-throughput

0.282

High

789867

CBP4
Assembly factor CBP4

1

0

High-throughput

0.282

High

799714

CUE1
Coupling of ubiquitin conjugation to ER degradation protein 1

1

0

High-throughput

0.282

High

806422

GPI16
GPI transamidase component GPI16

1

0

High-throughput

0.282

High

921404

YTP1
Protein YTP1

1

0

High-throughput

0.282

High

1053097

RSA3
Ribosome assembly protein 3

1

0

High-throughput

0.282

High

1060322

POM34
Nucleoporin POM34

1

0

High-throughput

0.282

High

1060328

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4

1

0

High-throughput

0.282

High

583167

CUP2
Transcriptional activator protein CUP2

1

0

High-throughput

0.265

Low

441273

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.261

Low

917947

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.261

Low

1044788

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025