HitPredict

Interactor 1: HNF4G (Q14541)
Hepatocyte nuclear factor 4-gamma (HNF-4-gamma) (Nuclear receptor subfamily 2 group A member 2)
Gene: HNF4G

Interactor 2: NR0B2 (Q15466)
Nuclear receptor subfamily 0 group B member 2 (Orphan nuclear receptor SHP) (Small heterodimer partner)
Gene: NR0B2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	15604093
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Hormone_recep~Hormone_recep, Hormone_recep~zf-C4
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 408 Hs			1 257
+	Mm
		1143685 HNF4G_MOUSE (1-408): 5.9e-159: 455: 95.83		NR0B2_MOUSE (1-257): 2.21e-60: 193: 78.08
+	Hs
		782496 HNF4A_HUMAN (3-397): 2.74e-137: 402: 73.40		HNF4A_HUMAN (14-256): 1.42e-62: 205: 23.46
+	Mm
		830719 HNF4A_MOUSE (2-397): 1.27e-125: 372: 72.48		NR0B1_MOUSE (44-254): 6.11e-74: 234: 34.51
+	Hs
		782501 HNF4A_HUMAN (3-397): 2.74e-137: 402: 73.40		NR2C2_HUMAN (33-256): 6.58e-59: 198: 25.89
+	Hs
		782548 HNF4A_HUMAN (3-397): 2.74e-137: 402: 73.40		NR0B2_HUMAN (1-257): 1.01e-61: 196: 100.00
+	Hs
		525290 HNF4A_HUMAN (3-397): 2.74e-137: 402: 73.40		NR2C1_HUMAN (1-256): 9.99e-57: 192: 23.49
+	Hs
		587136 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		RXRA_HUMAN (20-254): 4.48e-68: 219: 22.13
+	Hs
		818876 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		NR0B2_HUMAN (1-257): 1.01e-61: 196: 100.00
+	Hs
		490054 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		NR2F6_HUMAN (2-255): 1.04e-58: 193: 27.59
+	Hs
		818867 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		NR1H2_HUMAN (26-253): 1.16e-56: 189: 19.74
+	Mm
		659754 RXRG_MOUSE (3-329): 3.53e-118: 353: 40.24		NR1H2_MOUSE (26-253): 4.44e-57: 190: 20.18
+	Hs
		93999 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		F1D8P7_HUMAN (26-253): 1.52e-56: 188: 19.74
+	Mm
		659690 RXRA_MOUSE (5-328): 7.85e-119: 355: 41.39		NR1H3_MOUSE (3-253): 2.18e-55: 185: 16.15
+	Mm
		659756 RXRG_MOUSE (3-329): 3.53e-118: 353: 40.24		NR1H3_MOUSE (3-253): 2.18e-55: 185: 16.15
+	Hs
		818871 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		NR1H3_HUMAN (2-253): 8.41e-55: 183: 15.71
+	Hs
		487920 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		RARA_HUMAN (49-254): 9.48e-54: 181: 17.48
+	Mm
		509288 RXRA_MOUSE (5-328): 7.85e-119: 355: 41.39		RARA_MOUSE (48-254): 9.26e-53: 179: 17.39
+	Hs
		500357 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		RARB_HUMAN (5-254): 1.41e-52: 178: 16.54
+	Hs
		611397 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		NR4A1_HUMAN (6-256): 4.44e-50: 174: 18.46
+	Hs
		818881 RXRG_HUMAN (3-329): 7.16e-119: 355: 40.54		Q86UC5_HUMAN (5-254): 3.09e-52: 174: 16.54