HitPredict

Interactor 1: G5ECY6 (G5ECY6)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (RING-type E3 ubiquitin transferase CHIP)
Gene: chn-1

Interactor 2: G5ECY6 (G5ECY6)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (RING-type E3 ubiquitin transferase CHIP)
Gene: chn-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.709

The method score is based on:

Property Details
Experiments 36027913
Identification Methods two hybrid, pull down, enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CHIP_TPR_N~CHIP_TPR_N, CHIP_TPR_N~U-box, TPR_1~TPR_1, TPR_1~TPR_8, TPR_8~TPR_8, U-box~U-box
Common GO terms GO:0000209 - protein polyubiquitination
GO:0005737 - cytoplasm
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins
GO:0008340 - determination of adult lifespan
GO:0016567 - protein ubiquitination
and 14 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 266
Ce

1 266
+ Mm
+ Hs
+ Mm
+ Hs
+ Ps
+ Dm
+ Mm
+ Hs
+ Rn
+ Hs
+ Ce
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024