HitPredict

Interactor 1: NBR1 (Q14596)
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
Gene: NBR1

Interactor 2: GBRL1 (Q9H0R8)
Gamma-aminobutyric acid receptor-associated protein-like 1 (Early estrogen-regulated protein) (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)
Gene: GABARAPL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	19250911, 23022382, 20562859
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 966 Hs			1 117
+	Hs
		891147 NBR1_HUMAN (1-966): 0: 1811: 100.00		GBRL2_HUMAN (1-116): 1.39e-57: 175: 61.21
+	Hs
		306175 NBR1_HUMAN (1-966): 0: 1811: 100.00		GBRAP_HUMAN (1-116): 2.96e-56: 171: 87.07
+	Hs
		1056120 NBR1_HUMAN (1-966): 0: 1811: 100.00		MLP3C_HUMAN (5-116): 1.61e-44: 143: 39.47
+	Hs
		1056129 NBR1_HUMAN (1-966): 0: 1811: 100.00		MLP3A_HUMAN (5-116): 1.09e-44: 142: 34.21
+	Hs
		1056123 NBR1_HUMAN (1-966): 0: 1811: 100.00		MLP3B_HUMAN (2-116): 1.06e-43: 140: 31.62
+	Mm
		956458 NBR1_MOUSE (1-966): 0: 1731: 82.15		MLP3A_MOUSE (5-116): 1.09e-44: 142: 34.21
+	At
		1227908 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8A_ARATH (2-116): 3.39e-62: 186: 56.52
+	At
		1351949 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8D_ARATH (3-116): 6.55e-62: 186: 56.14
+	At
		1248233 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8C_ARATH (2-116): 1.74e-61: 185: 54.78
+	At
		1351950 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8B_ARATH (2-116): 4.66e-61: 184: 55.65
+	At
		1258022 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8F_ARATH (2-116): 7.47e-61: 183: 54.78
+	At
		1339372 NBR1_ARATH (363-479): 3.2e-43: 170: 33.88		ATG8I_ARATH (3-116): 9.59e-54: 165: 44.74