Interactor 1: ITPR1 (Q14643)
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5 trisphosphate receptor) (Inositol 1,4,5-trisphosphate receptor type 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)
Gene: ITPR1

Interactor 2: TRPC4 (Q9UBN4)
Short transient receptor potential channel 4 (TrpC4) (Trp-related protein 4) (hTrp-4) (hTrp4)
Gene: TRPC4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 14505576, 11163362
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~Ion_trans
Common GO terms GO:0005886 - plasma membrane
GO:0006816 - calcium ion transport
GO:0070679 - inositol 1,4,5 trisphosphate binding
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2758
Hs

1 977
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Last updated: 15 Jul 2024