Protein: BFR2
Protein BFR2 (Brefeldin A resistance protein 2)

Gene: BFR2
Organism: Saccharomyces cerevisiae S288C
Interactions: 143
UniProt ID: Q06631

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0015031 - protein transport
GO:0016192 - vesicle-mediated transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

818352

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

5

4

Small-scale

0.723

High

677579

KRR1
KRR1 small subunit processome component

5

1

High-throughput

0.716

High

678469

PWP2
Periodic tryptophan protein 2

5

3

Small-scale

0.712

High

871064

NOL10
Ribosome biogenesis protein ENP2

4

2

Small-scale

0.700

High

798324

ENP1
Essential nuclear protein 1

5

1

Small-scale

0.699

High

918835

UTP22
U3 small nucleolar RNA-associated protein 22

4

1

High-throughput

0.697

High

632749

DBP4
ATP-dependent RNA helicase HCA4

3

2

Small-scale

0.680

High

1056339

NOP14
Nucleolar complex protein 14

3

1

High-throughput

0.667

High

924642

NAT10
RNA cytidine acetyltransferase

3

1

High-throughput

0.650

High

1046046

DHR1
Probable ATP-dependent RNA helicase DHR1

3

2

High-throughput

0.640

High

1055491

NOC4
Nucleolar complex protein 4

3

1

Small-scale

0.640

High

1054897

ESF1
Pre-rRNA-processing protein ESF1

3

0

High-throughput

0.634

High

865182

MPP10
U3 small nucleolar RNA-associated protein MPP10

2

1

Small-scale

0.621

High

826218

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

512669

RS6A
Small ribosomal subunit protein eS6A

2

1

High-throughput

0.584

High

763633

UTP20
U3 small nucleolar RNA-associated protein 20

2

1

High-throughput

0.584

High

844627

UTP10
U3 small nucleolar RNA-associated protein 10

2

1

High-throughput

0.584

High

1042245

TOM1
E3 ubiquitin-protein ligase TOM1

2

1

High-throughput

0.584

High

1046800

UTP14
U3 small nucleolar RNA-associated protein 14

2

1

High-throughput

0.584

High

1053519

UTP21
U3 small nucleolar RNA-associated protein 21

2

4

Small-scale

0.584

High

1056315

UTP4
U3 small nucleolar RNA-associated protein 4

2

3

Small-scale

0.584

High

1056336

NOP58
Nucleolar protein 58

2

2

High-throughput

0.584

High

722286

XPO1
Exportin-1

2

2

Small-scale

0.560

High

673238

RRP7
Ribosomal RNA-processing protein 7

2

0

High-throughput

0.559

High

1056323

BMS1
Ribosome biogenesis protein BMS1

2

0

High-throughput

0.559

High

546419

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.536

High

820398

RIO2
Serine/threonine-protein kinase RIO2

1

1

High-throughput

0.536

High

503259

RS22A
Small ribosomal subunit protein uS8A

2

1

High-throughput

0.533

High

525272

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.504

High

518139

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.501

High

440973

CDC7
Cell division control protein 7

1

1

High-throughput

0.489

High

149970

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

435382

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

435636

RS9B
Small ribosomal subunit protein uS4B

1

3

High-throughput

0.479

High

512161

RS4A
Small ribosomal subunit protein eS4A

1

1

High-throughput

0.479

High

513239

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

674852

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

747053

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

3

High-throughput

0.479

High

747595

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

753601

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

754342

DCA13
Protein SOF1

1

2

High-throughput

0.479

High

778550

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

782111

RL1D1
Ribosome biogenesis protein UTP30

1

1

High-throughput

0.479

High

802405

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

802910

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.479

High

804756

RRP4
Exosome complex component RRP4

1

1

High-throughput

0.479

High

817641

UTP7
U3 small nucleolar RNA-associated protein 7

1

3

High-throughput

0.479

High

825568

UTP25
U3 small nucleolar RNA-associated protein 25

1

1

High-throughput

0.479

High

863142

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

918900

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

919009

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

923260

ESF2
Pre-rRNA-processing protein ESF2

1

1

High-throughput

0.479

High

924194

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

High-throughput

0.479

High

925205

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.479

High

1036418

UTP6
U3 small nucleolar RNA-associated protein 6

1

1

High-throughput

0.479

High

1039860

UTP17
NET1-associated nuclear protein 1

1

4

High-throughput

0.479

High

1045112

UTP5
U3 small nucleolar RNA-associated protein 5

1

4

High-throughput

0.479

High

1046260

UTP15
U3 small nucleolar RNA-associated protein 15

1

2

High-throughput

0.479

High

1050177

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.479

High

1051714

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

1053116

UTP13
U3 small nucleolar RNA-associated protein 13

1

5

High-throughput

0.479

High

1054543

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

1

High-throughput

0.479

High

1055433

RRP9
Ribosomal RNA-processing protein 9

1

3

High-throughput

0.479

High

1056317

RCL1
rRNA processing protein RCL1

1

1

High-throughput

0.479

High

1056318

RRP44
Exosome complex exonuclease DIS3

1

1

High-throughput

0.479

High

1056327

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.479

High

1056329

UTP12
U3 small nucleolar RNA-associated protein 12

1

4

High-throughput

0.479

High

1056330

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

1056334

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

1056337

RRP12
Ribosomal RNA-processing protein 12

1

1

High-throughput

0.479

High

436187

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

442127

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

672958

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

689681

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

758415

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

804964

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

806582

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

808316

RRP8
25S rRNA

1

0

High-throughput

0.458

High

812686

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

823394

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.458

High

825089

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

852612

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

864527

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.458

High

864969

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

871131

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

919180

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

923990

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.458

High

1051166

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

1053785

SGD1
Suppressor of glycerol defect protein 1

1

0

High-throughput

0.458

High

1056319

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

1056321

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

1056324

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

1056326

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

1056333

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.458

High

1056335

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

1056340

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

509732

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

High-throughput

0.457

High

645980

DBF2
Cell cycle protein kinase DBF2

1

1

High-throughput

0.457

High

1040424

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

1

High-throughput

0.457

High

819898

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

1054989

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

433864

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

436528

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.437

High

455280

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

504432

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

514852

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

710002

BMH1
Protein BMH1

1

1

High-throughput

0.437

High

779354

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.437

High

792264

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.437

High

1056322

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

1056328

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.437

High

1056338

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.437

High

742483

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

1056332

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

657003

BUR1
Serine/threonine-protein kinase BUR1

1

0

High-throughput

0.279

Low

810669

SSN3
Meiotic mRNA stability protein kinase SSN3

1

0

High-throughput

0.279

Low

1042320

PKH3
Serine/threonine-protein kinase PKH3

1

0

High-throughput

0.279

Low

656888

KC12
Casein kinase I homolog 2

1

0

High-throughput

0.261

Low

999595

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.251

Low

1056331

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.251

Low

383909

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

410353

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

453032

CBP8
Cytochrome B pre-mRNA-processing protein 1

1

0

High-throughput

0.249

Low

644996

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.249

Low

708289

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

735181

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

797797

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

808918

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.249

Low

826090

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.249

Low

826866

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

874545

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

918465

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

1033584

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

1046312

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

1053975

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

1055561

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

1056320

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

1056325

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.249

Low

864065

MRX5
MIOREX complex component 5

1

0

High-throughput

0.238

Low

1056316

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.238

Low

393392

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.232

Low

806999

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.232

Low

863758

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025