HitPredict

Interactor 1: RASA3 (Q14644)
Ras GTPase-activating protein 3 (GAP1(IP4BP)) (Ins P4-binding protein)
Gene: RASA3

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RasGAP
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 834 Hs			1 236
+	Hs
		925282 RASA3_HUMAN (1-834): 0: 887: 100.00		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		892375 RASA3_HUMAN (1-834): 0: 887: 100.00		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		545380 RASA3_HUMAN (1-834): 0: 887: 100.00		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		894015 RASA3_HUMAN (1-834): 0: 887: 100.00		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		1056349 RASA3_HUMAN (1-834): 0: 887: 100.00		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27
+	Hs
		809347 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Mm
		925821 IQGA1_MOUSE (114-807): 1.18e-105: 359: 14.29		RAC1_MOUSE (32-217): 3.34e-76: 230: 53.23
+	Hs
		809264 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		809396 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		809255 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		809233 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		564448 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		545255 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		809241 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Mm
		892736 IQGA1_MOUSE (114-807): 1.18e-105: 359: 14.29		CDC42_MOUSE (32-207): 2.12e-66: 205: 57.39
+	Hs
		809234 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		809436 IQGA1_HUMAN (114-807): 2.1e-101: 347: 14.18		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27
+	Hs
		892356 IQGA2_HUMAN (56-817): 1.1e-81: 289: 13.62		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		564517 IQGA2_HUMAN (56-817): 1.1e-81: 289: 13.62		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		893981 IQGA2_HUMAN (56-817): 1.1e-81: 289: 13.62		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39