HitPredict

Interactor 1: TRIPC (Q14669)
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)
Gene: TRIP12

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27248496
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006974 - DNA damage response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1992 Hs			1 626
+	Hs
		1056609 TRIPC_HUMAN (1-1992): 0: 1579: 100.00		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		125717 WWP2_HUMAN (1053-1990): 0: 603: 18.31		WDR76_HUMAN (1-626): 1.19e-151: 453: 100.00
+	Sc
		975879 TOM1_YEAST (922-1992): 0: 644: 15.37		CMR1_YEAST (159-623): 1.38e-74: 249: 23.50
+	Hs
		125310 WWP2_HUMAN (1053-1990): 0: 603: 18.31		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		131473 IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73		COP1_HUMAN (154-619): 7.6e-71: 245: 14.96
+	Hs
		134934 IMA3_HUMAN (365-866): 1.41e-154: 488: 13.33		COP1_HUMAN (154-619): 7.6e-71: 245: 14.96
+	Hs
		131478 IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73		DDB2_HUMAN (201-625): 1.38e-70: 236: 21.51
+	Hs
		131484 IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		125412 WWP2_HUMAN (1053-1990): 0: 603: 18.31		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		131487 IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		903156 UBE3A_HUMAN (1492-1991): 2.41e-140: 462: 27.02		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	At
		1280914 IMPA1_ARATH (347-905): 5.44e-164: 514: 14.61		WDR26_ARATH (35-449): 2.87e-22: 103: 12.13
+	At
		97818 IMPA2_ARATH (347-905): 3.96e-160: 504: 15.32		WDR26_ARATH (35-449): 2.87e-22: 103: 12.13
+	Hs
		131421 IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		134883 IMA3_HUMAN (365-866): 1.41e-154: 488: 13.33		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55
+	Hs
		1281471 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		FBXW7_HUMAN (180-616): 3.15e-66: 231: 11.79
+	Hs
		903601 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		WDR5_HUMAN (435-622): 2.2e-42: 157: 12.23
+	Hs
		197105 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		PRP4_HUMAN (401-624): 5.45e-40: 155: 15.09
+	Hs
		1288384 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		SNR40_HUMAN (440-625): 1.07e-33: 134: 11.83
+	Hs
		997955 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		RBBP4_HUMAN (233-477): 2.84e-19: 92.6: 14.55