HitPredict

Interactor 1: PUM1 (Q14671)
Pumilio homolog 1 (HsPUM) (Pumilio-1)
Gene: PUM1

Interactor 2: RBMS2 (Q15434)
RNA-binding motif, single-stranded-interacting protein 2 (Suppressor of CDC2 with RNA-binding motif 3)
Gene: RBMS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29395067, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1186 Hs			1 407
+	Hs
		668357 PUM1_HUMAN (1-1186): 0: 1508: 100.00		RBMS1_HUMAN (49-407): 4.15e-70: 228: 72.10
+	Hs
		1031329 PUM1_HUMAN (1-1186): 0: 1508: 100.00		PABP4_HUMAN (48-225): 4.57e-42: 158: 21.39
+	Hs
		516519 PUM1_HUMAN (1-1186): 0: 1508: 100.00		PABP1_HUMAN (48-254): 1.4e-39: 151: 20.83
+	Hs
		1020260 PUM1_HUMAN (1-1186): 0: 1508: 100.00		ELAV2_HUMAN (58-128): 2.41e-17: 84.6: 28.17
+	Hs
		1056720 PUM1_HUMAN (1-1186): 0: 1508: 100.00		PABP5_HUMAN (63-197): 6.9e-09: 59.3: 26.39
+	Hs
		1073808 PUM2_HUMAN (128-1186): 0: 1188: 76.67		RBMS2_HUMAN (1-407): 5.02e-84: 263: 100.00
+	Hs
		668394 PUM2_HUMAN (128-1186): 0: 1188: 76.67		RBMS1_HUMAN (49-407): 4.15e-70: 228: 72.10
+	Hs
		516599 PUM2_HUMAN (128-1186): 0: 1188: 76.67		PABP1_HUMAN (48-254): 1.4e-39: 151: 20.83
+	Hs
		1020295 PUM2_HUMAN (128-1186): 0: 1188: 76.67		ELAV2_HUMAN (58-128): 2.41e-17: 84.6: 28.17
+	Hs
		1252108 PUM2_HUMAN (128-1186): 0: 1188: 76.67		PABP5_HUMAN (63-197): 6.9e-09: 59.3: 26.39
+	Dm
		597047 PUM_DROME (429-1180): 0: 592: 45.62		PABP_DROME (57-197): 3.08e-09: 60.8: 24.67
+	Sc
		376947 PUF3_YEAST (466-1074): 2.78e-31: 134: 16.92		PABP_YEAST (4-302): 1.65e-19: 92.6: 14.05