Interactor 1: ESPL1 (Q14674)
Separin (EC 3.4.22.49) (Caspase-like protein ESPL1) (Extra spindle poles-like 1 protein) (Separase)
Gene: ESPL1

Interactor 2: RFFL (Q8WZ73)
E3 ubiquitin-protein ligase rififylin (EC 2.3.2.27) (Caspase regulator CARP2) (Caspases-8 and -10-associated RING finger protein 2) (CARP-2) (FYVE-RING finger protein Sakura) (Fring) (RING finger and FYVE-like domain-containing protein 1) (RING finger protein 189) (RING finger protein 34-like) (RING-type E3 ubiquitin transferase rififylin)
Gene: RFFL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 0.55 0.480

The method score is based on:

Property Details
Experiments 22626734
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024