Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 29656893, 21293379
Identification Methods proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT_2~BRCT_2, FHA~FHA
Common GO terms GO:0000076 - DNA replication checkpoint signaling
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005925 - focal adhesion
and 9 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2089
Hs

1 2089
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Zm
+ Dm
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs

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Last updated: 15 Jul 2024