Protein: SON
Protein SON (Bax antagonist selected in saccharomyces 1) (BASS1) (Negative regulatory element-binding protein) (NRE-binding protein) (Protein DBP-5) (SON3)

Gene: SON
Organism: Homo sapiens
Interactions: 169
UniProt ID: P18583

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000281 - mitotic cytokinesis
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0006397 - mRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

615363

SRPK2
SRSF protein kinase 2

5

20

High-throughput

0.718

High

615339

IF4A3
Eukaryotic initiation factor 4A-III

1

4

High-throughput

0.691

High

615447

DDX21
Nucleolar RNA helicase 2

1

5

High-throughput

0.691

High

371117

MYC
Myc proto-oncogene protein

3

12

High-throughput

0.640

High

615349

CLK2
Dual specificity protein kinase CLK2

2

15

High-throughput

0.628

High

615436

SRPK1
SRSF protein kinase 1

2

20

High-throughput

0.628

High

615385

DHX8
ATP-dependent RNA helicase DHX8

1

5

High-throughput

0.618

High

615457

SRPK3
SRSF protein kinase 3

3

20

High-throughput

0.616

High

615357

1433G
14-3-3 protein gamma

2

20

High-throughput

0.612

High

134552

SAP18
Histone deacetylase complex subunit SAP18

2

2

High-throughput

0.611

High

615384

RBM39
RNA-binding protein 39

2

8

High-throughput

0.611

High

615413

ZCH18
Zinc finger CCCH domain-containing protein 18

2

11

High-throughput

0.611

High

615393

RNPS1
RNA-binding protein with serine-rich domain 1

2

9

High-throughput

0.601

High

446626

NPM
Nucleophosmin

2

2

High-throughput

0.584

High

615365

MECOM
Histone-lysine N-methyltransferase MECOM

2

4

High-throughput

0.584

High

615419

SNIP1
Smad nuclear-interacting protein 1

2

3

High-throughput

0.576

High

615452

DDX41
Probable ATP-dependent RNA helicase DDX41

1

5

High-throughput

0.575

High

615341

CCNF
Cyclin-F

2

0

High-throughput

0.559

High

285801

SF3B1
Splicing factor 3B subunit 1

1

5

High-throughput

0.536

High

477912

SNRPA
U1 small nuclear ribonucleoprotein A

1

5

High-throughput

0.536

High

480029

RU1C
U1 small nuclear ribonucleoprotein C

1

3

High-throughput

0.536

High

541816

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.536

High

574138

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

4

High-throughput

0.536

High

615329

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.536

High

615345

KI67
Proliferation marker protein Ki-67

1

14

High-throughput

0.536

High

615355

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.536

High

615358

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

615370

SRSF1
Serine/arginine-rich splicing factor 1

1

17

High-throughput

0.536

High

615371

SRSF4
Serine/arginine-rich splicing factor 4

1

15

High-throughput

0.536

High

615372

SSRP1
FACT complex subunit SSRP1

1

11

High-throughput

0.536

High

615378

SRSF5
Serine/arginine-rich splicing factor 5

1

15

High-throughput

0.536

High

615379

SRSF6
Serine/arginine-rich splicing factor 6

1

17

High-throughput

0.536

High

615394

SF3A1
Splicing factor 3A subunit 1

1

8

High-throughput

0.536

High

615396

SRSF7
Serine/arginine-rich splicing factor 7

1

15

High-throughput

0.536

High

615397

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

11

High-throughput

0.536

High

615405

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

1

High-throughput

0.536

High

615423

PSPC1
Paraspeckle component 1

1

8

High-throughput

0.536

High

395458

ESR1
Estrogen receptor

2

20

High-throughput

0.521

High

615395

EZH2
Histone-lysine N-methyltransferase EZH2

1

8

High-throughput

0.515

High

615346

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

280497

PR40A
Pre-mRNA-processing factor 40 homolog A

1

13

High-throughput

0.508

High

615340

VHL
von Hippel-Lindau disease tumor suppressor

1

3

Small-scale

0.501

High

615415

CLIP4
CAP-Gly domain-containing linker protein 4

1

4

High-throughput

0.494

High

212007

M3K13
Mitogen-activated protein kinase kinase kinase 13

1

3

High-throughput

0.489

High

244223

NUAK1
NUAK family SNF1-like kinase 1

1

5

High-throughput

0.489

High

615333

GRK4
G protein-coupled receptor kinase 4

1

4

High-throughput

0.489

High

615351

NEK3
Serine/threonine-protein kinase Nek3

1

4

High-throughput

0.489

High

615420

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.489

High

615426

KIFA3
Kinesin-associated protein 3

1

8

High-throughput

0.489

High

615432

HDA11
Histone deacetylase 11

1

4

High-throughput

0.489

High

615458

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

7

High-throughput

0.489

High

615461

RPKL1
Ribosomal protein S6 kinase-like 1

1

5

High-throughput

0.489

High

156939

CTRO
Citron Rho-interacting kinase

1

12

High-throughput

0.479

High

222706

PRC1
Protein regulator of cytokinesis 1

1

4

High-throughput

0.479

High

240703

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

248269

HBP1
HMG box-containing protein 1

1

9

High-throughput

0.479

High

271884

OBSL1
Obscurin-like protein 1

1

13

High-throughput

0.479

High

325680

UBR5
E3 ubiquitin-protein ligase UBR5

1

5

High-throughput

0.479

High

330650

KI20A
Kinesin-like protein KIF20A

1

16

High-throughput

0.479

High

345350

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

11

High-throughput

0.479

High

400248

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

405776

MYCN
N-myc proto-oncogene protein

1

13

High-throughput

0.479

High

472445

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

7

High-throughput

0.479

High

519727

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

536464

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

606190

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.479

High

615328

U2AF2
Splicing factor U2AF 65 kDa subunit

1

9

High-throughput

0.479

High

615332

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

615338

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

12

High-throughput

0.479

High

615344

GATA4
Transcription factor GATA-4

1

4

High-throughput

0.479

High

615350

MECP2
Methyl-CpG-binding protein 2

1

6

High-throughput

0.479

High

615353

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

615356

MGN
Protein mago nashi homolog

1

2

High-throughput

0.479

High

615360

H4
Histone H4

1

5

High-throughput

0.479

High

615362

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.479

High

615364

KIF23
Kinesin-like protein KIF23

1

9

High-throughput

0.479

High

615366

TF65
Transcription factor p65

1

6

High-throughput

0.479

High

615368

MTG8
Protein CBFA2T1

1

1

Small-scale

0.479

High

615374

EP300
Histone acetyltransferase p300

1

17

High-throughput

0.479

High

615376

MKRN3
E3 ubiquitin-protein ligase makorin-3

1

1

High-throughput

0.479

High

615380

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.479

High

615386

CUL7
Cullin-7

1

4

High-throughput

0.479

High

615389

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

7

High-throughput

0.479

High

615390

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

615398

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

615410

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

16

High-throughput

0.479

High

615411

SLN11
Schlafen family member 11

1

1

High-throughput

0.479

High

615414

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

615418

NUP43
Nucleoporin Nup43

1

11

High-throughput

0.479

High

615421

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

615425

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

615429

FUBP1
Far upstream element-binding protein 1

1

6

High-throughput

0.479

High

615430

CHCH1
Small ribosomal subunit protein mS37

1

1

High-throughput

0.479

High

615433

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

10

High-throughput

0.479

High

615439

RBM4B
RNA-binding protein 4B

1

5

High-throughput

0.479

High

615443

CHM4B
Charged multivesicular body protein 4b

1

6

High-throughput

0.479

High

615444

ECT2
Protein ECT2

1

7

High-throughput

0.479

High

615446

RC3H2
Roquin-2

1

11

High-throughput

0.479

High

615448

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

615451

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

1

High-throughput

0.479

High

615331

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.470

High

615387

SUZ12
Polycomb protein SUZ12

1

2

High-throughput

0.470

High

587412

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.458

High

615369

FMR1
Fragile X messenger ribonucleoprotein 1

1

12

High-throughput

0.457

High

529038

TAU
Microtubule-associated protein tau

1

10

Small-scale

0.445

High

615352

NCBP2
Nuclear cap-binding protein subunit 2

1

6

High-throughput

0.445

High

615373

NCBP1
Nuclear cap-binding protein subunit 1

1

1

High-throughput

0.445

High

615442

PININ
Pinin

1

2

High-throughput

0.445

High

615343

MAGA6
Melanoma-associated antigen 6

1

3

High-throughput

0.439

High

128763

MEN1
Menin

1

3

High-throughput

0.437

High

259413

BRD4
Bromodomain-containing protein 4

1

14

High-throughput

0.437

High

285071

EED
Polycomb protein EED

1

17

High-throughput

0.437

High

293175

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

587878

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

615330

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

615334

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.437

High

615335

PHB1
Prohibitin 1

1

1

High-throughput

0.437

High

615336

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

615337

VGFR2
Vascular endothelial growth factor receptor 2

1

5

High-throughput

0.437

High

615347

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.437

High

615348

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

1

High-throughput

0.437

High

615359

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.437

High

615367

TLE3
Transducin-like enhancer protein 3

1

10

High-throughput

0.437

High

615375

MERTK
Tyrosine-protein kinase Mer

1

14

High-throughput

0.437

High

615377

RFA4
Replication protein A 30 kDa subunit

1

4

High-throughput

0.437

High

615382

CUL3
Cullin-3

1

17

High-throughput

0.437

High

615383

GRM2
Metabotropic glutamate receptor 2

1

1

High-throughput

0.437

High

615388

TNIP1
TNFAIP3-interacting protein 1

1

14

High-throughput

0.437

High

615391

BRD3
Bromodomain-containing protein 3

1

14

High-throughput

0.437

High

615406

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

615407

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.437

High

615409

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

14

High-throughput

0.437

High

615412

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.437

High

615416

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.437

High

615427

ATOH1
Transcription factor ATOH1

1

2

Small-scale

0.437

High

615431

DCPS
m7GpppX diphosphatase

1

2

High-throughput

0.437

High

615434

CIC
Protein capicua homolog

1

16

High-throughput

0.437

High

615437

RING2
E3 ubiquitin-protein ligase RING2

1

11

High-throughput

0.437

High

615440

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.437

High

615441

FACD2
Fanconi anemia group D2 protein

1

5

High-throughput

0.437

High

615445

PRD16
Histone-lysine N-methyltransferase PRDM16

1

3

High-throughput

0.437

High

615449

NLE1
Notchless protein homolog 1

1

2

High-throughput

0.437

High

615450

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.437

High

615453

FBW1B
F-box/WD repeat-containing protein 11

1

5

High-throughput

0.437

High

615456

HECD1
E3 ubiquitin-protein ligase HECTD1

1

13

High-throughput

0.437

High

615400

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

615454

TNIK
TRAF2 and NCK-interacting protein kinase

1

3

High-throughput

0.417

High

213062

CP110
Centriolar coiled-coil protein of 110 kDa

1

1

High-throughput

0.407

High

615342

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

2

High-throughput

0.407

High

615401

ODFP2
Outer dense fiber protein 2

1

7

High-throughput

0.407

High

615402

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.407

High

615403

CE170
Centrosomal protein of 170 kDa

1

20

High-throughput

0.407

High

615404

CP135
Centrosomal protein of 135 kDa

1

6

High-throughput

0.407

High

615417

POC5
Centrosomal protein POC5

1

1

High-throughput

0.407

High

615422

CE192
Centrosomal protein of 192 kDa

1

1

High-throughput

0.407

High

615438

DHB14
L-fucose dehydrogenase

1

0

High-throughput

0.279

Low

615392

PEA15
Astrocytic phosphoprotein PEA-15

1

0

Small-scale

0.251

Low

615354

BID
BH3-interacting domain death agonist

1

0

Small-scale

0.249

Low

615361

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.249

Low

615399

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

615408

SAMD7
Sterile alpha motif domain-containing protein 7

1

0

High-throughput

0.249

Low

615428

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.249

Low

615455

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.249

Low

615459

CIA2B
Cytosolic iron-sulfur assembly component 2B

1

0

High-throughput

0.249

Low

615460

FBX7
F-box only protein 7

1

0

High-throughput

0.249

Low

190304

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.232

Low

615381

UT1
Urea transporter 1

1

0

High-throughput

0.232

Low

615424

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.232

Low

615435

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025