HitPredict

Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: FUBP2 (Q92945)
Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75)
Gene: KHSRP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29656893
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2089 Hs			1 711
+	Hs
		1056922 MDC1_HUMAN (1-2089): 0: 665: 100.00		FUBP1_HUMAN (70-707): 2.96e-89: 294: 58.65
+	Hs
		1019058 TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87		FUBP2_HUMAN (1-689): 4.89e-129: 400: 100.00
+	Hs
		801285 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		FUBP2_HUMAN (1-689): 4.89e-129: 400: 100.00
+	Hs
		1019062 TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87		FUBP1_HUMAN (70-707): 2.96e-89: 294: 58.65
+	Hs
		801293 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		FUBP1_HUMAN (70-707): 2.96e-89: 294: 58.65
+	Hs
		1154062 NIPBL_HUMAN (869-1889): 2.17e-21: 104: 15.13		FUBP2_HUMAN (1-689): 4.89e-129: 400: 100.00
+	Hs
		1283832 MINT_HUMAN (159-1473): 1.72e-10: 68.9: 10.33		FUBP1_HUMAN (70-707): 2.96e-89: 294: 58.65
+	Hs
		801306 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		FUBP3_HUMAN (211-701): 4.22e-25: 112: 20.63
+	Hs
		801160 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		PCBP1_HUMAN (52-397): 2.33e-25: 110: 14.25
+	Dm
		58917 A2VEF9_DROME (913-2046): 1.95e-56: 218: 11.68		M9NF14_DROME (178-682): 4.1e-21: 100: 14.42
+	Hs
		1072118 PAXI1_HUMAN (1840-2081): 6.55e-55: 212: 27.56		PCBP2_HUMAN (52-400): 2.58e-22: 101: 15.28
+	Dm
		2450 SPEN_DROME (86-1912): 1.19e-59: 231: 7.60		NOVA_DROME (151-310): 6.19e-11: 67.8: 29.88
+	Hs
		1072114 NIPBL_HUMAN (869-1889): 2.17e-21: 104: 15.13		PCBP2_HUMAN (52-400): 2.58e-22: 101: 15.28
+	Hs
		1294286 PRC2C_HUMAN (145-1944): 8.04e-16: 86.5: 8.07		FUBP3_HUMAN (211-701): 4.22e-25: 112: 20.63
+	Hs
		903992 NIPBL_HUMAN (869-1889): 2.17e-21: 104: 15.13		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		1349186 PRC2C_HUMAN (145-1944): 8.04e-16: 86.5: 8.07		IF2B1_HUMAN (61-231): 3.23e-10: 65.5: 16.76
+	Hs
		1377929 PRC2C_HUMAN (145-1944): 8.04e-16: 86.5: 8.07		IF2B2_HUMAN (61-211): 4.12e-10: 65.1: 20.26
+	Hs
		965165 ANK2_HUMAN (608-1849): 1.3e-11: 72.7: 10.40		IF2B1_HUMAN (61-231): 3.23e-10: 65.5: 16.76