Protein: FMR1
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1) (mFmr1p)

Gene: FMR1
Organism: Mus musculus
Interactions: 240
UniProt ID: P35922

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000775 - chromosome, centromeric region
GO:0002092 - positive regulation of receptor internalization
GO:0002151 - G-quadruplex RNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

777902

FXR1
RNA-binding protein FXR1

2

14

Small-scale

0.737

High

777842

PCBP1
Poly(rC)-binding protein 1

1

13

High-throughput

0.575

High

777873

FUBP2
Far upstream element-binding protein 2

1

15

High-throughput

0.575

High

777993

ANR17
Ankyrin repeat domain-containing protein 17

1

7

High-throughput

0.575

High

778020

FXR2
RNA-binding protein FXR2

1

14

High-throughput

0.575

High

778005

RCAN1
Calcipressin-1

1

0

Small-scale

0.458

High

684900

FLI1
Friend leukemia integration 1 transcription factor

1

1

High-throughput

0.457

High

59323

CKAP5
Cytoskeleton-associated protein 5

1

6

High-throughput

0.445

High

59362

VIR
Protein virilizer homolog

1

1

High-throughput

0.445

High

59400

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

15

High-throughput

0.445

High

59679

UBR4
E3 ubiquitin-protein ligase UBR4

1

3

High-throughput

0.445

High

59739

SKT
Sickle tail protein

1

2

High-throughput

0.445

High

60458

BLT3B
Bridge-like lipid transfer protein family member 3B

1

2

High-throughput

0.445

High

73941

OTUD4
OTU domain-containing protein 4

1

9

High-throughput

0.445

High

97709

E9PWI3
Mutated in colorectal cancers

1

5

High-throughput

0.445

High

97847

TENS1
Tensin-1

1

1

High-throughput

0.445

High

98216

NUMA1
Nuclear mitotic apparatus protein 1

1

9

High-throughput

0.445

High

104472

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

4

High-throughput

0.445

High

147410

BIN1
Myc box-dependent-interacting protein 1

1

3

High-throughput

0.445

High

147467

DPYL2
Dihydropyrimidinase-related protein 2

1

4

High-throughput

0.445

High

148513

NUMBL
Numb-like protein

1

4

High-throughput

0.445

High

148556

NCOA3
Nuclear receptor coactivator 3

1

3

High-throughput

0.445

High

204440

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

1

High-throughput

0.445

High

204618

PURB
Transcriptional regulator protein Pur-beta

1

5

High-throughput

0.445

High

236390

SRPK2
SRSF protein kinase 2

1

6

High-throughput

0.445

High

236404

DAPK3
Death-associated protein kinase 3

1

11

High-throughput

0.445

High

237319

LDB2
LIM domain-binding protein 2

1

3

High-throughput

0.445

High

266843

ATX2
Ataxin-2

1

12

High-throughput

0.445

High

312227

KLC1
Kinesin light chain 1

1

3

High-throughput

0.445

High

312526

ZFR
Zinc finger RNA-binding protein

1

12

High-throughput

0.445

High

312895

BSN
Protein bassoon

1

17

High-throughput

0.445

High

313114

HDAC3
Histone deacetylase 3

1

7

High-throughput

0.445

High

470768

NFL
Neurofilament light polypeptide

1

14

High-throughput

0.445

High

480961

NUCL
Nucleolin

1

9

High-throughput

0.445

High

548936

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

18

High-throughput

0.445

High

558528

CNTN1
Contactin-1

1

2

High-throughput

0.445

High

777977

ZNFX1
NFX1-type zinc finger-containing protein 1

1

7

High-throughput

0.445

High

777978

DOCK7
Dedicator of cytokinesis protein 7

1

3

High-throughput

0.445

High

777979

CACB1
Voltage-dependent L-type calcium channel subunit beta-1

1

5

High-throughput

0.445

High

777980

LUZP1
Leucine zipper protein 1

1

11

High-throughput

0.445

High

777981

CCAR2
Cell cycle and apoptosis regulator protein 2

1

6

High-throughput

0.445

High

777982

MIOS
GATOR2 complex protein MIOS

1

2

High-throughput

0.445

High

777983

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

9

High-throughput

0.445

High

777984

GOGA4
Golgin subfamily A member 4

1

17

High-throughput

0.445

High

777985

UBAP2
Ubiquitin-associated protein 2

1

20

High-throughput

0.445

High

777986

TDRD3
Tudor domain-containing protein 3

1

6

High-throughput

0.445

High

777987

DLG2
Disks large homolog 2

1

9

High-throughput

0.445

High

777988

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

2

High-throughput

0.445

High

777989

SP16H
FACT complex subunit SPT16

1

1

High-throughput

0.445

High

777990

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

3

High-throughput

0.445

High

777991

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

18

High-throughput

0.445

High

777992

HOME3
Homer protein homolog 3

1

14

High-throughput

0.445

High

777994

PARD3
Partitioning defective 3 homolog

1

18

High-throughput

0.445

High

777995

BC11B
B-cell lymphoma/leukemia 11B

1

8

High-throughput

0.445

High

568877

DNMT1
DNA

1

5

High-throughput

0.445

High

654688

CBX3
Chromobox protein homolog 3

1

4

High-throughput

0.445

High

704207

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

18

High-throughput

0.445

High

704269

NCKP1
Nck-associated protein 1

1

1

High-throughput

0.445

High

704808

KIF5C
Kinesin heavy chain isoform 5C

1

16

High-throughput

0.445

High

704826

KIF2A
Kinesin-like protein KIF2A

1

8

High-throughput

0.445

High

749841

KIF5A
Kinesin heavy chain isoform 5A

1

16

High-throughput

0.445

High

777828

DYN1
Dynamin-1

1

4

High-throughput

0.445

High

777829

ZO1
Tight junction protein 1

1

8

High-throughput

0.445

High

777830

PURA
Transcriptional activator protein Pur-alpha

1

5

High-throughput

0.445

High

777831

RAGP1
Ran GTPase-activating protein 1

1

2

High-throughput

0.445

High

777833

AINX
Alpha-internexin

1

14

High-throughput

0.445

High

777834

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

8

High-throughput

0.445

High

777836

CENPC
Centromere protein C

1

5

High-throughput

0.445

High

777837

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

4

High-throughput

0.445

High

777839

APC1
Anaphase-promoting complex subunit 1

1

1

High-throughput

0.445

High

777840

ZNRD2
Protein ZNRD2

1

2

High-throughput

0.445

High

777841

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

777843

MO4L1
Mortality factor 4-like protein 1

1

4

High-throughput

0.445

High

777845

ARF3
ADP-ribosylation factor 3

1

1

High-throughput

0.445

High

777846

EST1A
Telomerase-binding protein EST1A

1

6

High-throughput

0.445

High

777847

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

2

High-throughput

0.445

High

777848

TRA2B
Transformer-2 protein homolog beta

1

15

High-throughput

0.445

High

777849

IF4E
Eukaryotic translation initiation factor 4E

1

2

Small-scale

0.445

High

777850

MK01
Mitogen-activated protein kinase 1

1

3

High-throughput

0.445

High

777851

DYL1
Dynein light chain 1, cytoplasmic

1

3

High-throughput

0.445

High

777852

KPCG
Protein kinase C gamma type

1

8

High-throughput

0.445

High

777853

KPCB
Protein kinase C beta type

1

5

High-throughput

0.445

High

777854

RANB9
Ran-binding protein 9

1

10

High-throughput

0.445

High

777855

IMB1
Importin subunit beta-1

1

3

High-throughput

0.445

High

777856

HDAC2
Histone deacetylase 2

1

10

High-throughput

0.445

High

777857

ELAV1
ELAV-like protein 1

1

16

High-throughput

0.445

High

777858

RAD50
DNA repair protein RAD50

1

7

High-throughput

0.445

High

777859

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

5

High-throughput

0.445

High

777860

TP53B
TP53-binding protein 1

1

6

High-throughput

0.445

High

777861

LDB1
LIM domain-binding protein 1

1

3

High-throughput

0.445

High

777863

TNIK
Traf2 and NCK-interacting protein kinase

1

9

High-throughput

0.445

High

777864

ERH
Enhancer of rudimentary homolog

1

2

High-throughput

0.445

High

777865

G3BP2
Ras GTPase-activating protein-binding protein 2

1

9

High-throughput

0.445

High

777866

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

9

High-throughput

0.445

High

777867

CTNB1
Catenin beta-1

1

6

High-throughput

0.445

High

777868

EMAL1
Echinoderm microtubule-associated protein-like 1

1

8

High-throughput

0.445

High

777869

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

4

High-throughput

0.445

High

777870

CTP5A
Contactin-associated protein like 5-1

1

1

High-throughput

0.445

High

777871

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

14

High-throughput

0.445

High

777872

PRC2C
Protein PRRC2C

1

20

High-throughput

0.445

High

777874

DIP2B
Disco-interacting protein 2 homolog B

1

2

High-throughput

0.445

High

777875

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

7

High-throughput

0.445

High

777876

MTCL1
Microtubule cross-linking factor 1

1

13

High-throughput

0.445

High

777877

EDC4
Enhancer of mRNA-decapping protein 4

1

12

High-throughput

0.445

High

777879

KDM5A
Lysine-specific demethylase 5A

1

1

High-throughput

0.445

High

777881

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

10

High-throughput

0.445

High

777882

HERC2
E3 ubiquitin-protein ligase HERC2

1

12

High-throughput

0.445

High

777883

TR150
Thyroid hormone receptor-associated protein 3

1

12

High-throughput

0.445

High

777884

IQEC2
IQ motif and SEC7 domain-containing protein 2

1

4

High-throughput

0.445

High

777885

NUFP2
FMR1-interacting protein NUFIP2

1

5

High-throughput

0.445

High

777886

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

1

8

High-throughput

0.445

High

777887

BRSK1
Serine/threonine-protein kinase BRSK1

1

5

High-throughput

0.445

High

777888

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

9

High-throughput

0.445

High

777889

LMTK3
Serine/threonine-protein kinase LMTK3

1

13

High-throughput

0.445

High

777890

ICAM5
Intercellular adhesion molecule 5

1

1

High-throughput

0.445

High

777891

CSK21
Casein kinase II subunit alpha

1

10

High-throughput

0.445

High

777892

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

12

High-throughput

0.445

High

777893

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.445

High

777894

CAPR1
Caprin-1

1

8

High-throughput

0.445

High

777895

ARHG2
Rho guanine nucleotide exchange factor 2

1

11

High-throughput

0.445

High

777896

ELAV2
ELAV-like protein 2

1

16

High-throughput

0.445

High

777897

ELAV3
ELAV-like protein 3

1

16

High-throughput

0.445

High

777898

NCOR1
Nuclear receptor corepressor 1

1

15

High-throughput

0.445

High

777899

NCOA2
Nuclear receptor coactivator 2

1

3

High-throughput

0.445

High

777900

APC
Adenomatous polyposis coli protein

1

19

High-throughput

0.445

High

777901

EWS
RNA-binding protein EWS

1

8

High-throughput

0.445

High

777903

ELAV4
ELAV-like protein 4

1

16

High-throughput

0.445

High

777904

KINH
Kinesin-1 heavy chain

1

16

High-throughput

0.445

High

777905

KPCD1
Serine/threonine-protein kinase D1

1

12

High-throughput

0.445

High

777906

DLG4
Disks large homolog 4

1

7

High-throughput

0.445

High

777907

SIN3B
Paired amphipathic helix protein Sin3b

1

1

High-throughput

0.445

High

777908

DDX3X
ATP-dependent RNA helicase DDX3X

1

8

High-throughput

0.445

High

777909

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

7

High-throughput

0.445

High

777910

TIF1B
Transcription intermediary factor 1-beta

1

16

High-throughput

0.445

High

777911

GIT1
ARF GTPase-activating protein GIT1

1

8

High-throughput

0.445

High

777912

PKP4
Plakophilin-4

1

9

High-throughput

0.445

High

777915

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.445

High

777916

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

6

High-throughput

0.445

High

777918

ZN219
Zinc finger protein 219

1

7

High-throughput

0.445

High

777919

NIPBL
Nipped-B-like protein

1

13

High-throughput

0.445

High

777920

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

6

High-throughput

0.445

High

777922

HDAC4
Histone deacetylase 4

1

11

High-throughput

0.445

High

777923

SIK3
Serine/threonine-protein kinase SIK3

1

1

High-throughput

0.445

High

777924

CSKI1
Caskin-1

1

4

High-throughput

0.445

High

777925

ARHGI
Rho guanine nucleotide exchange factor 18

1

8

High-throughput

0.445

High

777926

SMRC2
SWI/SNF complex subunit SMARCC2

1

11

High-throughput

0.445

High

777927

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

11

High-throughput

0.445

High

777928

DLGP3
Disks large-associated protein 3

1

4

High-throughput

0.445

High

777929

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

18

High-throughput

0.445

High

777930

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

19

High-throughput

0.445

High

777931

WDFY3
WD repeat and FYVE domain-containing protein 3

1

13

High-throughput

0.445

High

777932

GGYF2
GRB10-interacting GYF protein 2

1

7

High-throughput

0.445

High

777934

CNOT1
CCR4-NOT transcription complex subunit 1

1

3

High-throughput

0.445

High

777935

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.445

High

777936

AKAP9
A-kinase anchor protein 9

1

17

High-throughput

0.445

High

777937

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

2

High-throughput

0.445

High

777938

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

9

Small-scale

0.445

High

777939

PLPR4
Phospholipid phosphatase-related protein type 4

1

1

High-throughput

0.445

High

777940

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

11

High-throughput

0.445

High

777942

WTIP
Wilms tumor protein 1-interacting protein

1

3

High-throughput

0.445

High

777943

PRC2A
Protein PRRC2A

1

20

High-throughput

0.445

High

777944

NISCH
Nischarin

1

4

High-throughput

0.445

High

777945

CLAP1
CLIP-associating protein 1

1

4

High-throughput

0.445

High

777946

C170B
Centrosomal protein of 170 kDa protein B

1

11

High-throughput

0.445

High

777947

SCRIB
Protein scribble homolog

1

8

High-throughput

0.445

High

777948

UBP2L
Ubiquitin-associated protein 2-like

1

20

High-throughput

0.445

High

777949

DIXC1
Dixin

1

7

High-throughput

0.445

High

777950

SAFB2
Scaffold attachment factor B2

1

20

High-throughput

0.445

High

777951

DLG1
Disks large homolog 1

1

7

High-throughput

0.445

High

777952

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

1

4

High-throughput

0.445

High

777953

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

8

High-throughput

0.445

High

777955

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

4

High-throughput

0.445

High

777956

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

4

High-throughput

0.445

High

777957

PB1
Protein polybromo-1

1

13

High-throughput

0.445

High

777958

TENR
Tenascin-R

1

3

High-throughput

0.445

High

777960

DZAN1
Double zinc ribbon and ankyrin repeat-containing protein 1

1

1

High-throughput

0.445

High

777961

PAK5
Serine/threonine-protein kinase PAK 5

1

5

High-throughput

0.445

High

777962

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

6

High-throughput

0.445

High

777964

RHG24
Rho GTPase-activating protein 24

1

7

High-throughput

0.445

High

777965

SPICE
Spindle and centriole-associated protein 1

1

1

High-throughput

0.445

High

777966

ITCH
E3 ubiquitin-protein ligase Itchy

1

8

High-throughput

0.445

High

777967

CACB2
Voltage-dependent L-type calcium channel subunit beta-2

1

5

High-throughput

0.445

High

777968

WDR47
WD repeat-containing protein 47

1

13

High-throughput

0.445

High

777969

RPGF2
Rap guanine nucleotide exchange factor 2

1

2

High-throughput

0.445

High

777970

AGO2
Protein argonaute-2

1

15

High-throughput

0.445

High

777971

AGO1
Protein argonaute-1

1

16

High-throughput

0.445

High

777972

MATR3
Matrin-3

1

3

High-throughput

0.445

High

777973

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

High-throughput

0.445

High

777974

CASC3
Protein CASC3

1

4

High-throughput

0.445

High

777975

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

4

High-throughput

0.445

High

777976

CACB4
Voltage-dependent L-type calcium channel subunit beta-4

1

5

High-throughput

0.445

High

777996

BCL9
B-cell CLL/lymphoma 9 protein

1

8

High-throughput

0.445

High

777997

DLGP1
Disks large-associated protein 1

1

4

High-throughput

0.445

High

777998

NOSIP
Nitric oxide synthase-interacting protein

1

1

High-throughput

0.445

High

777999

AKAP8
A-kinase anchor protein 8

1

3

High-throughput

0.445

High

778000

TSC1
Hamartin

1

11

High-throughput

0.445

High

778001

NBEA
Neurobeachin

1

8

High-throughput

0.445

High

778002

TCF20
Transcription factor 20

1

11

High-throughput

0.445

High

778003

RBP2
E3 SUMO-protein ligase RanBP2

1

4

High-throughput

0.445

High

778004

AFF4
AF4/FMR2 family member 4

1

20

High-throughput

0.445

High

778006

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

0.445

High

778007

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.445

High

778008

HAKAI
E3 ubiquitin-protein ligase Hakai

1

10

High-throughput

0.445

High

778009

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

8

High-throughput

0.445

High

778010

KI21B
Kinesin-like protein KIF21B

1

19

High-throughput

0.445

High

778011

EHD3
EH domain-containing protein 3

1

5

High-throughput

0.445

High

778012

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4

1

8

High-throughput

0.445

High

778013

BC11A
BCL11 transcription factor A

1

9

High-throughput

0.445

High

778014

MAGD1
Melanoma-associated antigen D1

1

8

High-throughput

0.445

High

778015

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.445

High

778016

PCM1
Pericentriolar material 1 protein

1

4

High-throughput

0.445

High

778017

TRIM3
Tripartite motif-containing protein 3

1

11

High-throughput

0.445

High

778018

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.445

High

778019

GSK3B
Glycogen synthase kinase-3 beta

1

6

High-throughput

0.445

High

778021

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

3

High-throughput

0.445

High

778022

ZSC12
Zinc finger and SCAN domain-containing protein 12

1

9

High-throughput

0.445

High

778023

APCL
Adenomatous polyposis coli protein 2

1

13

High-throughput

0.445

High

778024

MBD3
Methyl-CpG-binding domain protein 3

1

1

High-throughput

0.445

High

778025

TOP3B
DNA topoisomerase 3-beta-1

1

6

High-throughput

0.445

High

777838

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.426

High

59051

F1712
Protein FAM171A2

1

3

High-throughput

0.407

High

59820

A2ATK9
Family with sequence similarity 171, member A1

1

3

High-throughput

0.407

High

95463

MTCL2
Microtubule cross-linking factor 2

1

10

High-throughput

0.407

High

236468

CSK22
Casein kinase II subunit alpha'

1

6

High-throughput

0.407

High

267218

DIAP2
Protein diaphanous homolog 2

1

2

High-throughput

0.407

High

777832

NSF
Vesicle-fusing ATPase

1

3

High-throughput

0.407

High

777835

PCNT
Pericentrin

1

14

High-throughput

0.407

High

777844

ACTZ
Alpha-centractin

1

4

High-throughput

0.407

High

777862

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

1

High-throughput

0.407

High

777878

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

1

5

High-throughput

0.407

High

777880

5NTC
Cytosolic purine 5'-nucleotidase

1

2

High-throughput

0.407

High

777913

Q69ZK1
NEDD4-binding protein 2-like 2

1

3

High-throughput

0.407

High

777914

CE170
Centrosomal protein of 170 kDa

1

12

High-throughput

0.407

High

777917

RHG21
Rho GTPase-activating protein 21

1

7

High-throughput

0.407

High

777921

MTCL3
Microtubule cross-linking factor 3

1

11

High-throughput

0.407

High

777933

KCNT1
Potassium channel subfamily T member 1

1

3

High-throughput

0.407

High

777941

PRC2B
Protein PRRC2B

1

20

High-throughput

0.407

High

777954

ZC21A
Zinc finger C2HC domain-containing protein 1A

1

1

High-throughput

0.407

High

777959

LMO3
LIM domain only protein 3

1

5

High-throughput

0.407

High

777963

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

6

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025