HitPredict

Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: FUBP1 (Q96AE4)
Far upstream element-binding protein 1 (FBP) (FUSE-binding protein 1) (DNA helicase V) (hDH V)
Gene: FUBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29656893
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2089 Hs			1 644
+	Hs
		1056915 MDC1_HUMAN (1-2089): 0: 665: 100.00		FUBP2_HUMAN (26-626): 1.33e-102: 329: 56.06
+	Hs
		1019062 TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87		FUBP1_HUMAN (1-644): 3.57e-120: 373: 100.00
+	Hs
		801293 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		FUBP1_HUMAN (1-644): 3.57e-120: 373: 100.00
+	Hs
		1019058 TP53B_HUMAN (166-1970): 5.58e-75: 280: 8.87		FUBP2_HUMAN (26-626): 1.33e-102: 329: 56.06
+	Hs
		801285 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		FUBP2_HUMAN (26-626): 1.33e-102: 329: 56.06
+	Hs
		1283832 MINT_HUMAN (159-1473): 1.72e-10: 68.9: 10.33		FUBP1_HUMAN (1-644): 3.57e-120: 373: 100.00
+	Hs
		1154062 NIPBL_HUMAN (869-1889): 2.17e-21: 104: 15.13		FUBP2_HUMAN (26-626): 1.33e-102: 329: 56.06
+	Hs
		801306 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		FUBP3_HUMAN (168-629): 3.66e-31: 130: 18.94
+	Hs
		801160 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		PCBP1_HUMAN (7-173): 7.39e-14: 75.5: 20.24
+	Dm
		58917 A2VEF9_DROME (913-2046): 1.95e-56: 218: 11.68		M9NF14_DROME (134-630): 4.03e-22: 102: 14.18
+	Hs
		1072118 PAXI1_HUMAN (1840-2081): 6.55e-55: 212: 27.56		PCBP2_HUMAN (21-353): 4.85e-23: 103: 15.78
+	Dm
		2450 SPEN_DROME (86-1912): 1.19e-59: 231: 7.60		NOVA_DROME (189-349): 9.62e-09: 60.5: 27.55
+	Hs
		1294286 PRC2C_HUMAN (145-1944): 8.04e-16: 86.5: 8.07		FUBP3_HUMAN (168-629): 3.66e-31: 130: 18.94
+	Hs
		1072114 NIPBL_HUMAN (869-1889): 2.17e-21: 104: 15.13		PCBP2_HUMAN (21-353): 4.85e-23: 103: 15.78
+	Hs
		1349186 PRC2C_HUMAN (145-1944): 8.04e-16: 86.5: 8.07		IF2B1_HUMAN (86-271): 2.86e-25: 112: 22.46
+	Hs
		965165 ANK2_HUMAN (608-1849): 1.3e-11: 72.7: 10.40		IF2B1_HUMAN (86-271): 2.86e-25: 112: 22.46
+	Hs
		1377929 PRC2C_HUMAN (145-1944): 8.04e-16: 86.5: 8.07		IF2B2_HUMAN (255-561): 2.31e-17: 87.8: 14.38
+	Ce
		1325687 CLA1_CAEEL (759-1822): 3.41e-16: 87.8: 14.15		Q9GRY9_CAEEL (269-412): 3.99e-09: 61.2: 29.73